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Caring for a Three Legged Dog or Cat

Tripawds is the place to learn how to care for a three legged dog or cat, with answers about dog leg amputation, and cat amputation recovery from many years of member experiences.
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Osteosarcoma Metronomics advice
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Member Since:
4 November 2021
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1
27 September 2022 - 6:40 pm
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My greyhound had his rear right leg amputated last year due to osteosarcoma. There were no signs of the cancer spreading then, but now a very tiny growth suspected to be cancer is showing in his lungs (0.05%). I’m looking into metronomic‘s to see if there’s anything we can do to help extend his life that doesn’t negatively affect him. I’m wondering if anyone has any first-hand experience with success with any of these options listed below and if there were bad side effects.

1. antiangiogenic therapy (alkalating agent/low dose chemo, with NSAID/Metacam, doxycycline, & fish oil)
2. Palladia Tablets (with Pepcid or cerenia for nausea, & prednisone)
3. Surgical removal of lesions or growths from the lungs
4. Aratana Therapeutics vaccine (AT-014)
Have any of you tried low-dose chemotherapy/anti-angiogenic medicine, like Cytoxan, Algarin, etc. and had good success with minimal side effects?
Thanks for any info & help!
The Rainbow Bridge


Member Since:
25 April 2007
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27 September 2022 - 7:04 pm
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Hi Betty & Pup, welcome! What’s your dog’s name? Glad to know that he is doing well and thriving! And it’s super cool that you are being proactive.

Have you asked your oncologist about which treatment is best for him? I would start there. 

Meanwhile, we have lots of info about these paths you can take. Check out these links and let us know what sounds good to you. 

1. antiangiogenic therapy (alkalating agent/low dose chemo, with NSAID/Metacam, doxycycline, & fish oil)

Lung Metastasis in Tripawds with Limb Cancer: Now What?

2. Palladia Tablets (with Pepcid or cerenia for nausea, & prednisone )

Tripawd Limb Cancer Treatments with Bisphosphonates, Palladia

3. Surgical removal of lesions or growths from the lungs

There’s a new technique that is doing amazing things! We are running a feature on it soon in Tripawds News:

Minimally Invasive Metastasectomy in Canines (MIMIC)

New Treatment for Bone and Lung Tumors in Dogs and Cats at UW

An Update on Treating Lung Metastasis in Dogs

4. Aratana Therapeutics vaccine (AT-014)

This vaccine is no longer being offered as far as I know, but Torigen and ELIAS are making really good ones with great results so far:

New Immunotherapy for Pet Cancer Study Results are Pawesome!

Torigen Immunotherapy Vaccine: Hope for Pets with Cancer Podcast

Also check out Bowie the Greyhound’s story:

Bowie’s Canine Osteosarcoma Vaccine Experience

Have any of you tried low-dose chemotherapy/anti-angiogenic medicine, like Cytoxan, Algarin, etc. and had good success with minimal side effects?

We did have good success with no side effects. However, this type of metronomics is currently being phased out since it’s been shown to not be as effective as previously thought. See:

Lung Metastasis in Tripawds with Limb Cancer: Now What?

Also see our list of articles on each topic:

https://tripawd…..tronomics/

https://tripawd…..notherapy/

https://tripawd…..etastasis/

We are so glad you are here! Your future posts won’t need approval so post away.

Member Since:
4 November 2021
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27 September 2022 - 7:13 pm
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Thanks Jerry — I read a lot of your stories!

His name is Dash because he is a fast runner! He’s a retired racing greyhound, we don’t support racing dogs & are happy we can spoil him now.
I work from home since 2020, so I get to feed him treats and homemade food every day!

i’ll check out the links, im hoping we can help him live longer without causing any pain. We’re having our first baby in December & I hope he gets to meet her <3

Virginia




Member Since:
22 February 2013
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27 September 2022 - 7:32 pm
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Dash is mighty lucky boy to have such strong advocates for him, checking out options, etc.. 

Sounds like Dash (great name for Greyhound) is feeling  just fine and that’s  good news.  Sure, none wants to hear long mets, but it doesn’t  mean this is the end of the road by any means!  So many dogs have gotten continued good quality  time in spite of a pesky met.

Jerry has given you so many good links to discuss  with the Onco.

When my Hapoy Hannah developed a large met,  I did proceed with Metronomics for awhile.  Liked that it wasn’t  “invasive” and didn’t  really have side effects.  And, if I recall, I did add Prednisone  to keep any  inflammation  down the met may have caused.  Seems like Hapoh Hannah did develop a bladder infection  that may, or may not, have been caused by the Cytoxan.   Anyway, cleared it up with no issues.

Others can chime in on their Palladia, so take this comment  FWIW. It does seem for many there are strong side effects as far as causing the dog to feel yucky, not wanting to eat, etc. Anyway, discuss with your Vet.  Obviously not giving Vet advice. 

I have no doubt your sweet Dash will be there to welcome uour new baby home.  I’m sure he will be a Greyt Nanny👍

Keep is posted!

Higs

Sally and Alumni Happy Hannah and Merry Myrtle and Frankie too!

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

The Rainbow Bridge


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25 April 2007
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27 September 2022 - 10:16 pm
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Nice to meet you and Dash! He’s very lucky to have such a great family, and now he gets to be a big brother too? Very cool!

OK let us know what you decide to do. We are here for any questions or support!

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