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Yale Canine Cancer Vaccine Information
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The Rainbow Bridge



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6 May 2020 - 4:52 pm
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Wit thanks to Casey & Finn for sharing….

FYI, from the Yale School of Medicine Website:

The Yale Canine Cancer Vaccine Program offers a clinical trial through Yale School of Medicine’s (YSM) Section of Rheumatology, Allergy & Immunology to treat canines afflicted with cancer through a therapeutic vaccine in a phase I/II canine cancer vaccine trial. This canine cancer vaccine is designed to enhance immune responses to tumor proteins in canine cancers including osteosarcoma, hemangiosarcoma, nasopharyngeal cancer, some adenocarcinomas, breast and colon cancer. The vaccine therapy is intended to activate antibody responses against a family of cancer proteins known as EGFR/HER2. This study is being conducted in collaboration with Dr. Raymond Koski of L2 Diagnostics, LLC in New Haven, Conn. The study is also supported by the Canine Cancer Alliance.

Treatment

Dogs receive two vaccinations over a three-week period and are followed over the course of their disease, using blood work, MRI, CAT scans, and ultrasound. Some animals still receive chemotherapy, but it not the conventional chemotherapy without the side effects that afflict humans. If the pet is on chemotherapy (carboplatin or others), there needs to be three weeks between the last cycle of chemotherapy before beginning the vaccination.

Local veterinarians can administer the treatment!!!

For details visit the YSM website.

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16 August 2020 - 5:11 pm
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I wanted to share this vaccine study update from Copper. She developed a side-effect that may actually give her immune system more power to fight cancer. Thought it was interesting so here it is:

Copper got her 2nd Yale Canine Cancer Vaccine on 8/5. Just in case it helps anyone – about 6 days after the 1st vaccine Copper got an abscess at the injection site that started draining about a week later. For a while it looked like she was growing a second head (haha) and is currently still present.

When she went to get her 2nd vaccine last week – she got a really cute hair cut around it – and also around the area of the 2nd injection for me to keep an eye on it. At the visit they took a sample of the abscess (from the 1st injection) and there was some bacteria present, so she just finished a round of antibiotics. Surprisingly (to me) she got an abscess at the 2nd injection site within about 6 hours that started draining ~48 hours later.

Dr. Mamula told me prior to starting the vaccine that about 20% of patients develop a sterile abscess at the site of the vaccination and that typically it is found in patients that make among the best immune responses to the vaccine. So hopefully her bilateral abscesses just mean her immune system is on high alert. I’ve attached some pics below of the abscesses in question.

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