Well Harley saw the oncologist yesterday and it doesn't really look like the chlorambucil is doing much.  The tumors have grown a little more so the increase is now up about 13% from the original xrays early June.  13% is still considered "stable disease" but if stable disease is considered anything less than 20% (I thought last month she said 30% ??) and it was 6% last month and 13% this month I think it's safe to assume within another month he will no longer be considered stable.  Yesterday we talked about amputation to give him some relief, but when the oncologist called today she discussed debulking the tumor one more time and then possibly changing the metronomic protocol to cytoxan which has shown in some cases to slow the growth of liposarcomas.  And I guess that is assuming that the tumor on his limb is a liposarcoma and the lung tumors are metastasis from that.  Just more unknowns than knowns.  It's hard to tell what is the greater problem -- the circumference of his left leg is now almost 11" as opposed to his right leg which is only 7", and he still walks and runs but favors the leg and will hold it up while standing.  I don't really notice any symptoms with the lung tumors -- a little panting on rare occasion but weather seems to affect that so the A/C is running constantly.

Lots to think about.