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Dr. Rosenberg's Thoughts on Metronomics and Supplements
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The Rainbow Bridge

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10 April 2010 - 5:10 pm
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Pawrents who are unfamiliar with veterinary oncology practices are sometimes under the assumption that oncology care is intent on curing cancer at any cost. But this misconception couldn’t be further from the truth. Preserving quality of life is always the number one priority of veterinary oncology practitioners, like Dr. Mona Rosenberg’s team at the Veterinary Cancer Group of Southern California.

The Veterinary Cancer Group’s doctors and staff work with clients to determine the most effective treatments that can ensure the highest quality of life for every patient. If one method fails to sustain a good quality of life, other options can always be explored to ensure as happy and healthy life as possible.

One of these options is known as the Metronomic Protocol, or low-dose continuous chemotherapy (LDC). This therapy works by preventing blood-vessel proliferation by the tumor, starving it of nutrients that enable it to grow and spread.

(Read about Tripawd Founder Jerry’s Metronomic Protocol experience here).

In the last of our three part interview series with Dr. Mona Rosenberg (founder of the Veterinary Cancer Group of Southern California) she discusses the Metronomic Protocol. She also presents her approach for using nutritional supplements while undergoing cancer care treatments, and the importance of living with cancer, instead of living in fear of it.

Tripawds sincerely thanks Dr. Rosenberg and her staff at the Veterinary Cancer Group for allowing us to bring this important information to you.

Since 1992, the Veterinary Cancer Group of Southern California has been committed to taking the fear out of cancer and providing in-depth information and access to the latest treatments.

The Veterinary Cancer Group is the largest, most comprehensive and sophisticated veterinary oncology practice in the world, staffed by leading board-certified medical and radiation oncologists, oncology residents, technicians, assistants and client care specialists. Learn more about the Veterinary Cancer Group of Southern California by visiting their website at

Catch the other two parts of our Veterinary Cancer Group series:

Chemotherapy Session for Daisee Dog

Canine Bone Cancer News with Dr. Mona Rosenberg

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Los Angeles
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12 April 2010 - 4:00 pm
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Thanks so much for posting this – this is great information.  I discussed my next steps with my oncologist (who works at the VCG in LA) and we decided to go through with the metronomic protocol.  Since Mackenzie just got over a UTI, she wants to wait a couple of weeks before we start this protocol.  In the meantime, Mackenzie is taking Metacam (shown to be a good anti-cancer fighting non-steroid)  and when she starts the metronomic (cytoxan) she’ll also be prescribing a diuretic since this is known to cause bladder issues (irritation in the lining of the bladder) and pepcid ac if she needs that for any stomach issues from the metacam.  

Jerry, on your link on the metronomic experience, I noticed that you were also taking Doxycycline – this didn’t come up with my vet but I plan to discuss this with her since it sounds like a good antibiotic to take in addition to the cytoxan and metacam.  Do you know at what point in the protocol you started to take the doxycycline?

This protocol sounds very manageable and not too invasive the way some of these other chemo treatments can be, which is very welcoming.  And hopefully, Mackenzie will do well on this and we won’t have any issues for awhile laugh.

I also found Dr. Rosenberg’s comment on being able to fight cancer like a chronic disease (like how we fight diabetes, heart disease, etc.) such an eye opener – never thought about it that way before.  I really hope  someday soon that we will get to this point with cancer – being able to fight it like a chronic disease.  Wouldn’t that be so great?

Thanks again!

Kami (Mackenzie’s Mom)




My sweet golden Mackenzie.  She became my angel on Dec 29, 2010 at the age of 8 1/2  although she was always my angel from the time we brought her home.  She was diagnosed with osteosarcoma in Sept 2009 and officially became a tripawd (front leg) on Nov 5, 2009.  She will be forever in my heart and now she's running free with all of our other tripawd heroes.  I love you Mackenzie!

Here and Now

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12 April 2010 - 4:58 pm
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kbryant said:

Jerry, on your link on the metronomic experience … at what point in the protocol you started to take the doxycycline?


Jerry was prescribed the antibiotics at the same time we started him on the Cytoxan and Metcam. So, from the beginning of his metronomic treatment plan, he was taking all three: Doxycycline, Cytoxan, and Metacam.

We also started him on his K9 Immunity supplements at that time. Sorry if this wasn’t clear.

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12 April 2010 - 8:56 pm
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This was very helpful – thanks for posting it!  When we first met with Holly’s oncologist she mentioned metronomic therapy could be good once she finishes chemo.  I read through all the info here back then, but will need to reread it again once we’re close to finishing her chemo.  I agree with Kami – wouldn’t it be wonderful to be able to think of cancer as a chronic disease? It’s something we can hope for!

Holly joined the world of tripawds on 12/29/2009. She has a big little sister, Zuzu, who idolizes Holly and tries to make all of her toys into tripawds in Holly's honor. And she's enjoying life one hop at a time!

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