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Caring for a Three Legged Dog or Cat

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4 treatments vs 6 treatments of a carboplatin
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Colorado
Member Since:
15 March 2023
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1 April 2023 - 4:59 pm
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Hello!

Ellie starts her Carboplatin chemotherapy a week from Tuesday. She is in a clinical trial and they are going to do 4 treatments of Carboplatin (along with an additional oral drug that she has already started).

When I consulted with a private oncologist they suggested doing 6 treatments.

When I asked the clinical trial vet she said that there appears to be the same median survival rate whether it's 4 or 6 so it's not worth the money or putting the dog through more. But I've seen different posts on here where it seems different numbers of treatments are advised based on different factors. Does anyone have any opinions on this or studies that explore it?

The Rainbow Bridge



Member Since:
25 April 2007
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1 April 2023 - 6:21 pm
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Generally, treatment is anywhere from 4 to 6 rounds. It used to be that 6 was the gold standard, but recent studies show that it didn't make a difference after 4. Some vets are still doing 6 to cover their bases, but I believe it was the CSU vets who told us that 4 is the new standard they stick to.

Virginia







Member Since:
22 February 2013
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1 April 2023 - 9:17 pm
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I can only share that my Happy Hannah had four rounds of Carboplatin  as advised by her Oncologist. Basically her  Oncologist said exactly what your clinical trial Vet said.  I felt perfectly comfortable with the protocol of four rounds for her.

Hugs

Sally and Alumni Happy Hannah and Merry Myrtle and Frankie too!

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

Colorado
Member Since:
15 March 2023
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2 April 2023 - 8:09 am
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Thanks for the feedback!  And really nice to hear that she won't need to go through as much.

Curious to see if it gets adopted as the norm.

The Rainbow Bridge



Member Since:
25 April 2007
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2 April 2023 - 1:17 pm
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Yeah I think that if it hasn't been shown to make a difference, then why do them? 

As for making it into a standard, I hope so. Change is slow. A lot of times oncologists will continue doing what they find has worked well for their clients who share the same diagnosis. Nothing wrong with that, I get it. Sometimes it just takes a while to get the word out about the latest studies.

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