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Just saw this posting and figured I'd share in the hopes it might be an option for someone!
http://research.....eosarcoma/
Vaccine study for Dogs with Osteosarcoma
The University of Florida College of Veterinary Medicine is currently recruiting dogs recently diagnosed with osteosarcoma for a clinical research trial. This investigational trial is for the development of a vaccine for the future treatment of osteosarcoma in dogs.
- Inclusion Criteria: Any dog recently diagnosed osteosarcoma and does not have other life threatening diseases. The doctors will explain this to you. Your dog will have the vaccine in addition to whichever standard of care therapy you choose.
- Treatment: Participation involves4 visits. The vaccine will be given 4 times approximately 4 weeks apart. At each visit, blood will also be drawn to measure the immune response.
- Cost: The study will cover only the cost of the vaccine at each of the four visits (i.e. approximately $400 per dog for 4 vaccines) to a maximum of 20 dogs. Complications due to vaccine are not expected, but should any arise, the study will pay for those treatments directly associated with the injection site reaction to a maximum of $100.00. No other costs will be covered.
- Contact: Contact the Oncology Staff at the Small Animal Hospital 1-866-247-7950 or 352-392-2235 or Dr. Rowan Milner at milnerr@ufl.edu
Background:
Osteosarcoma is malignant cancer of both young humans and animals. The standard of care for humans and dogs with osteosarcoma is surgery followed by chemotherapy. Unfortunately, a large number of these osteosarcomas undergo early metastasis (spread) following surgery. This occurs even when surgery is done early and the tumor is removed in its entirety and chemotherapy is given. Infections of the osteosarcoma surgery site have been known to cause an immune reaction in people and animals improving overall survival. Since overall survival is dismal in patients with osteosarcoma, developing an osteosarcoma cancer vaccine holds promise as an adjunct treatment to surgery and chemotherapy. In a previous study of 400 dogs with melanoma we showed that a vaccine containing the ganglioside (GD3) causes a measurable immune response in normal dogs and dogs with melanoma and prolonged survival.
Thanks for sharing!
FYI: We've moved your topic here to the Tips and Resources forum where members share clinical trials and studies like this.
Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet
Very interesting, but I wish they didn't say that overall survival is "dismal". Such a negative word! Of course our pups are not going to "survive" OSA, but it makes it sound so hopeless.
Active 10+ Pyr mix suddenly came up lame with ACL tear in left rear leg. Scheduled for a TPLO but final pre-op x-rays indicated a small suspicious area, possibly OSA, which could have caused the ACL tear. Surgeon opened the knee for TPLO but found soft bone. Biopsy came back positive for OSA. Became a Tripawd 9/18/14. Carbo6 with Cerenia and Fluids. Pain free and living in the moment. Crossed the Bridge on 7/12/15 after probable spread of cancer to her cervical spine. A whole lifetime of memories squeezed into 10 months. Here's her story: Eloise
I agree, totally. That's like saying overall survival of life itself is dismal, after all, nobody lives forever (at least physically!). Society as a whole needs to change the outlook of living with cancer.
Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet
Another OSA study - great news (and at UFL - "Go Gators"!)
Absolutely right: there is a HUGE difference between living with cancer and dying from cancer. What is a survival rate for a large-breed dog? It all depends on their age. We are getting good survival rates (cross your paws and fingers) here at Tripawds with many of our OSA warriors.
People live with diabetes and other diseases, like AIDS, that were a death sentence if diagnosed twenty years ago. Cancer may well become a chronic disease like many others, to be controlled with medication. This would be a big breakthrough to prevent premature losses of young loved pets
Our awesome Golden Boy was diagnosed for OSA in April 2014 in the proximal humerus, front-leg amp on 05/20/2014. Finished chemo (Carbo6) on 07/10/2014. Ongoing treatment: acupuncture + K-9 Immunity Plus ( 3chews) and home-cooked no-grain diet. Stopped Apocaps because of liver issues. Liver issues: controlling altered enzymes with SAM-e and Milk Thistle. October 17: started having seizures. Taking fenobarbital for seizures. April 18: started prednisone.
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