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Caring for a Three Legged Dog or Cat

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Monoclonal antibody treatment for Arthritis
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London, UK

Member Since:
15 December 2015
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2 July 2021 - 4:35 am
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Thanks so much, Micelle, Rene, Sally...

Michelle, yes, I'm delighted with how she's doing. She's such a high energy dog that things get quite difficult to manage if she is very limited physically. Hopefully the pounds will come off and that will help her further. (and we're not discussing me either smiley2)

Rene, glad you enjoyed the video. It's lovely to see her so happy on the beach. BTW the wet you can see in the first video is not because it had been raining (for once...) but because I had to spray her buggy down to get all the salt and sand and sea water off it. We can't have the Mega Wagon going rusty. Re her age, she's been with me 11 1/2 years now, and she was at least a year when she came to me, probably more like 18 months, but I do agree she doesn't look (or act) her age. And yes, I hope this treatment will cross the pond too. The way people are raving about it here, I would imagine that there must be plans to license it in the US and Canada.

Sally, thank you. I'm pleased she seemed less stiff to you, and this was after a whole day on the beach! Frankie is welcome here ANY time, but I know you couldn't bear to be without him. Guess you and Myrtle will just have to come too icon_lol

Meg, Clare and Angel Pie xxx

Meg, Mutt, aged around 13, adopted 31/12/2009. Sudden explosive right elbow fracture 06/12 (caused by IOHC), diagnosed with End Stage Arthritis 03/15, Total Elbow Replacement 08/15, problems with healing leading to skin graft & skin flap surgery, Chronic Infection leading to implant breakdown. Became a Tripawd 9th March 2016. 
Lives with Mum, Clare, watched over by Angel Pie and Angel Billie
My life as a MEG-A-STAR 

On The Road

Member Since:
24 September 2009
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2 July 2021 - 2:50 pm
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Meg has reached so many milestones and achieved so much for a dog who supposedly wasn't a good candidate for amputation. HAH! She fooled them.

I was at a vet conference in 2018 when this therapy was presented in a few sessions about emerging therapies. I sure hope it gets here soon!

Tripawds Founders Jim and Rene | | |

The Rainbow Bridge

Member Since:
25 April 2007
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13 May 2022 - 8:02 pm
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megstamum said
This is a brand new treatment for arthritis which has just been licensed in the UK and EU and is showing extremely positive results in some dogs. It’s called Librela and I understand that a version for cats is shortly coming out too. It’s a monthly injection which inhibits the inflammatory process in the joints. Meg will be starting treatment shortly and I will report how we get on. 

More info here: https://todaysv.....-approval/

and also a video showing how it works



It's here! The new monoclonal antibodies arthritis treatment for cats is called Solensia here in the States. Just heard about it this week. Here's a link to the Zoetis Petcare Solensia website for more info.

The medication insert states that:

A 112-day, masked, randomized, controlled field study was conducted at 21 U.S. veterinary clinics.

The study enrolled 275 client-owned cats with clinical signs of osteoarthritis (OA) confirmed by radiography and orthopedic examination; enrolled cats weighed 2.5 to 11.4 kg and were 1.6 to 22.4 years old. The enrolled cats were randomized to treatment with SOLENSIA (n=182) or vehicle control (n=93), administered subcutaneously on Days 0, 28, and 56.

Cats were dosed with SOLENSIA (frunevetmab injection) or vehicle control based on body weight (2.5-7 kg cats received 1 mL, 7.1-14 kg cats received 2 mL).

The primary outcome measure for success for the control of pain associated with OA was comparison of the owner’s evaluation of CSOM at Day 56 compared to baseline (Day 0, before treatment). Treatment success was defined as a reduction of at least 2 in the total CSOM score at Day 56 compared with the score at baseline.

Cats that had an increase in any individual CSOM activity score (regardless of the total CSOM score) or that received rescue analgesia prior to Day 56 were considered treatment failures. Secondary outcome measures included the total CSOM score on Days 28 and 84; Owner Global Assessments on Days 28, 56, and 84; and total orthopedic pain score completed by the veterinarian on Days 28, 56, and 84. For the Owner Global Assessment, success was defined as an owner’s impression of the response to treatment as Good or Excellent (versus Fair or Poor). Success was not defined for the veterinary-assessed total orthopedic pain score. The proportion of cats considered treatment successes based on the owner

CSOM assessment and the Owner Global Assessment was greater in the SOLENSIA group compared to the control group for all assessments. The mean total orthopedic pain score was lower in the SOLENSIA group compared to the control group at all post-dosing assessments.

Twenty four of the Solensia cats had vomiting as a side effect, the most common. Others are listed on the insert. I think I would feel good about giving this to my own cat if I had one.

This new medication is a huge victory for feline pain control! 

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