Save time spent searching, download the new Tripawds e-book for immediate answers!

Bookmark Jerry's Required Reading List for more amputation recovery advice and care tips.

Review the Tripawds Featured Blogs for the best three legged dog care product recommendations.

Tripawds is a user supported community. Please do what you can to help keep it online.

Tripawd Talk Radio Interview with Speaking for Spot Author Dr. Nancy Kay
Miss the show? Listen to the podcast now!

Please consider registering
guest

Log In RegisterMembers

Register | Lost password?
Advanced Search:

— Forum Scope —



— Match —



— Forum Options —




Wildcard usage:
*  matches any number of characters    %  matches exactly one character

Minimum search word length is 4 characters - maximum search word length is 84 characters

Topic RSS
Gabapentin side effects, or...?
15 February 2011
8:26 pm
SoCal
Member
Forum Posts: 51
Member Since:
10 July 2010
Offline

Boomie started having seizures last week.   My vet started him on Gabapentin.   I’m not sure how effective it is, because he still has lots of little “spells” but at least the grand mal seizures have stopped for now.  Anyway, I am noticing that for the past few days, since he’s been on this drug, he has also been drinking more, and peeing more.   I couldn’t find anything that says this is a typical side effect of Gabapentin, so I thought I would check to see if anyone else has had this same experience.  If it’s not the drug, is there something else going on that might be causing both the drinking/peeing and the seizures?

Cindy and Boomie Boomie's leg was amputated due to osteosarcoma on May 15, 2008.  He enjoyed over two and a half years of life after that, one day at a time.  He died on Feb. 21, 2011.
15 February 2011
8:41 pm
Member
Forum Posts: 641
Member Since:
22 September 2010
Offline

I don't want to answer out of turn, as this is posted in the "Ask a Vet" topic, but a fairly common human side effect of the drug is hyperglycemia (high blood sugar) which results in exccessive thirst. Have you talked with your vet about this? It is something you would want to address sooner rather than later. It can also cause just a really dry mouth.

SWEET ISABELLE Rescued from Hurricane Katrina 09/17/2005 OSA diagnosed 08/19/2010. L rear leg amputated 08/24/2010         Resection of MCT in R rear leg 01/20/2011 Enjoying Her Fabulous Life at 13!
15 February 2011
8:42 pm
Pahrump, NV
Member
Forum Posts: 541
Member Since:
17 February 2010
Offline

The only thing I can think of is to check his blood sugar.  Diabetes can cause thirst/excess urination.  If that turns out ok, then maybe the vet can try phenobarbital instead of gabapentin.  I think most dogs that have siezures take phenobarb, unless it doesn't work, then they"ll try something else (like the gabapentin.)  Hope it's nothing serious.

Sadie is my 9yr old Rott/Shepherd mix. Diagnosed with osteosarcoma in her right scapula 1/28/10. Our brave girl had her amputation 2/13/10 and her last chemotherapy on 6/6/10. Unfortunately, a tumor appeared in her back right leg and on 10/7/2010 Sadie's earthly journey came to an end.  On 10/24/2010 we adopted Ranger, a handsome Rott/Lab mix tripawd (got hit by a car) I think Sadie sent him to us. http://ranger.t.....pawds.com/
15 February 2011
9:43 pm
Member
Forum Posts: 641
Member Since:
22 September 2010
Offline

Just to clarify…hyperglycemia, whatever the cause, can result in excessive thirst. Diabetes is a disease process, one symptom of which is hyperglycemia…gabapentin may cause hyperglycemia, but that doesn't mean an individual has diabetes, it just means the blood sugar is elevated. I would discuss these symptoms with your vet.

SWEET ISABELLE Rescued from Hurricane Katrina 09/17/2005 OSA diagnosed 08/19/2010. L rear leg amputated 08/24/2010         Resection of MCT in R rear leg 01/20/2011 Enjoying Her Fabulous Life at 13!
15 February 2011
9:50 pm
SoCal
Member
Forum Posts: 51
Member Since:
10 July 2010
Offline

Wouldn't you know it, my vet won't be in till Friday.  I guess I can ask the relief vet tomorrow (or the Doctor du Jour as I like to say).

Cindy and Boomie Boomie's leg was amputated due to osteosarcoma on May 15, 2008.  He enjoyed over two and a half years of life after that, one day at a time.  He died on Feb. 21, 2011.
15 February 2011
10:59 pm
Here and Now

Team Tripawds
Forum Posts: 7744
Member Since:
25 April 2007
Offline

Is Boomie getting liquid Gabapentin? If so be sure to ask if the prescription includes Xylitol which is poisonous to dogs.

A dog we knew has seizures for years, and he was treated regulary with Phenobarbitol.

"Dogs are born with three legs and a spare."
— Jerry G. Dawg (10/98-10/08)
Please Support Your Tripawds Community!
Have you started a Tripawds Blog yet?
Looking for quick answers? Download the new Tripawds eBook for the best tips and advice!

15 February 2011
11:05 pm
SoCal
Member
Forum Posts: 51
Member Since:
10 July 2010
Offline

He's getting the capsules.

Cindy and Boomie Boomie's leg was amputated due to osteosarcoma on May 15, 2008.  He enjoyed over two and a half years of life after that, one day at a time.  He died on Feb. 21, 2011.
16 February 2011
12:34 am

Moderator
Forum Posts: 1231
Member Since:
22 August 2008
Offline

I have not seen many side effects with gabapentin except for mild sedation in some dogs.  I know people that take the drug and have reported dizziness or dry mouth that usually goes away after a few days of starting.  I have monitored bloodwork on many dogs that are taking gabapentin (as well as Tramadol and an NSAID) and have not yet seen one with elevated blood sugar although I suppose it is possible.

It is unusual to prescribe gabapentin alone for grand mal seizures but it (or a drug called pregabalin) is often used for minor or psychomotor seizures.  More common seizure meds include phenobarbital or potassium bromide.  Did your vet give a steroid injection for any reason?  That class of drugs often causes increased thirst.

Did your dog start seizures recently?  Labs are prone to epilepsy which often shows up at 1-4 years of age.  Older dogs could have metabolic diseases or rarely cancer causing a seizure.  I would make sure your vet runs a blood and urine test and if he continues to seizure (even little episodes) he might need to have another anti-seizure drug added on.

Let me know if you still have questions…

Pam

16 February 2011
9:01 am
SoCal
Member
Forum Posts: 51
Member Since:
10 July 2010
Offline

The seizures started last week.  (Booomie is about 12 1/2) He did have a basic, non-fasting blood test on Friday.  It showed one liver value that was slightly high, but everything else was normal.  He had been on Metacam for over 3 years, and Tramadol for over one year, but we have stopped the Metacam and cut back on the Tramadol for now.   He has not had steroids.

This morning Boomie's excessive thirst and urination seem to be subsiding.  He is also having fewer seizures.  Most importantly, he is acting like his normal self.   I don't know why my vet didn't want to use those other drugs, unless she felt they might leave him too sedated or something.  I will be in contact with her soon.  Thanks.smiley

Cindy and Boomie Boomie's leg was amputated due to osteosarcoma on May 15, 2008.  He enjoyed over two and a half years of life after that, one day at a time.  He died on Feb. 21, 2011.
Forum Timezone: America/Denver

Most Users Ever Online: 165

Currently Online: etgayle
85 Guest(s)

Currently Browsing this Page:
1 Guest(s)

Top Posters:

AngelAbbysMom: 1498

Emilysmom: 1231

fightingforsammy: 1120

jakesmom: 1111

Cooper: 976

10711: 942

riosmom: 939

Cherry: 930

Member Stats:

Guest Posters: 442

Members: 3487

Moderators: 8

Admins: 3

Forum Stats:

Groups: 4

Forums: 22

Topics: 5883

Posts: 81370

Moderators: betaman (91), tazziedog (1231), hugapitbull (3175), testmod (7), Tazzie (1338), cometdog (4142), krun15 (2016), etgayle (1597)

Administrators: jerry (7607), admin (7744), jim (47)