Hi Kolbe's Mom, welcome! Thanks for chiming in on this discussion, we look forward to hearing about your jouuney. I know others with experience buying Palladia will offer ideas.

hhackett said
Here is an article published by the F.D.A...

Thanks for the link!

We always recommend people only purchase medication online from Vet-VIPPS accredited pharmacies. The NABP has a directory of Vet-VIPPS pharmacies.

For More Information:

Buy Pet Meds from a Vet-VIPPS Certified Online Pharmacy

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Know Where Your Pet Meds Come From

Hi CBB, welcome. Sorry to hear about your Grey. Have you talked to your vet about Palladia sources? Usually vets totally understand the high cost of this treatment and are willing to go above and beyond to get it as inexpensively (and safely) as possible.

As for Kinavet-CA1, Dr. Dressler and Ettinger discuss it here in the Dog Cancer TV blog. I feel entirely comfortable saying that if they give it a paws-up, it's worth a try. Dr. Ettinger says:

Dr. Susan Ettinger: So, Kinavet is in the same class of drugs such as Palladia. So, they’re both secret inhibitors. So, they’re both in this a new evolution of anticancer drugs called targeted therapy. What’s interesting and exciting about Kinavet is that, if your dog was on palladia and has developed a resistance or is not tolerant to it, you could try to other one. They have slightly difference, the effect and receptors. So, again there is reason to think that if your pet is resistant to one and you can try the other and it may still have some efficacy.

Here's some other info:

Veterinary Practice News: Mastocytoma Drug Gets Conditional OK

Kinavet-CA1 joins Pfizer Animal Health’s Palladia (toceranib phosphate), the first FDA-approved drug specifically for the treatment of cancer in dogs. Palladia, approved in 2009, also belongs to the tyrosine kinase inhibitor class of compounds.

While both drugs are targeted therapies, the mechanisms of action are different, Ahn noted.

AB Science describes Kinavet-CA1 as a tyrosine kinase inhibitor that targets mast cells, important cells for immunity, as well as a limited number of kinases that play key roles in various cancers.

“This drug is a targeted therapy,” Ahn said. “What this means is that it is specifically targeting receptors on the mast cell tumor in an effort to combat this disease.”

Older generation products or chemotherapeutic agents not only can damage the tumor, they may injure healthy tissue because they are nonspecific, he said. Tyrosine kinase inhibitors, on the other hand, are intended to be very specific in the mode of action.

I hadn't heard of this drug before, thanks for bringing it to our attention. Let us know what you find out.

Hi Sully's Mommy,

I'm happy to hear things are going well with Palladia. We know what a huge financial burden it is though, just so heartbreaking about how much it costs. And I'm so sorry, but that information about Palladia is very likely still correct. Wookie is a vet specialist, she knows these situations inside out and I honestly doubt anything's changed but it's good you're covering all your angles.

Have you talked to your vet about the situation? Most vets are willing to help clients find ways to cover costs.

Also, these links might help you connect with financial resource assistance:

http://download.....-pawrents/

If there's anything else we can do for you please don't hesitate to ask OK?