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Help - sick from MP
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Rock Hill, SC
Member Since:
28 November 2011
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1
27 June 2012 - 7:31 am
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Zeus took his first dose of MP chemo last night - 5 mg Peroxicam, 7 mg Cytoxan, 10 mg Prilosec to be taken once daily.  He took the meds with his meal at 6 pm last night and woke up this morning at 4 am vomiting (yellow liquid w/ very small amount of undigested food in it).  Seemed to feel better so I gave him breakfast at 6 am and an hour later he threw it all up.

I called the vet and he has instructed to stop all meds until he has not vomited for at least 24 to 48 hours.  Said we need to figure out which is causing the upset, so once he feels better I should give him the Cytoxan only and see how he tolerates it.

Zeus has always had a very sensitive stomach, but I thought MP was relatively mundane and low side effects?  Anyone else experience this?!

Lisa

Zeus was a Husky mix diagnosed with Osteosarcoma at age 11.  A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/

On The Road


Member Since:
24 September 2009
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27 June 2012 - 7:40 am
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Poor Zeus! He's got a sensitive belly for sure. My non-veterinary opinion is thinking it could be the Peroxicam, which I have heard can cause GI upset even when just taking it outside of metronomics (and it used to give me GI upset too). We used Meloxicam, which I understand is often easier on the belly than Peroxicam.  

I hope that he feels better soon!

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

Member Since:
13 October 2011
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27 June 2012 - 7:58 am
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Poor Love! No experience other than we know it is yucky to throw up!sad

 

Hope Sweet Zeus feels better soon!

Edmond, Oklahoma
Member Since:
7 January 2011
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27 June 2012 - 8:41 am
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Oh poor Zeus; nothing comes easy with this guy.  Hope he feels better soon.

-Catherine

Scout: January 31, 2002 to November 7, 2011

Scout's diagnosis was "poorly differentiated sarcoma"; amputation 1/11/2011.  Scout enjoyed 9 fantastic years on 4 legs and 9 glorious months on 3 legs.  If love alone could have saved you…

Member Since:
9 June 2012
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27 June 2012 - 9:13 am
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Sorry to hear this. I didn't know you could give chemo in tablets. I thought it only was given directly into the blood. Why have you been ordered tablets? Hope he will be better soon.

San Diego, CA
Member Since:
29 October 2010
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27 June 2012 - 9:21 am
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Oh no, I'm sorry to hear he's not feelnig good. As you know, Abby had no problems on her Cytox/Pirox regimine. I would guess it's probably the piroxicam as well.

I can't really remember, but I think I used to give Abby her ... not Prilosec, but the other one... Prevacid?? (You know I get them confused!)... anyway, whichever it was, I'd give it to her about 15 min before the rest of her pills. Don't know if that helped her tummy feel better w/ the pills, or if she just had a tough tummy.

Hope he feels better!
Jackie

Abby: Aug 1, 2009 – Jan 10, 2012. Our beautiful rescue pup lived LARGE with osteosarcoma for 15 months – half her way-too-short life. I think our "halflistic" approach (mixing traditional meds + supplements) helped her thrive. (PM me for details. I'm happy to help.) She had lung mets for over a year. They took her from us in the end, but they cannot take her spirit! She will live forever in our hearts. She loved the beach and giving kisses and going to In-N-Out for a Flying Dutchman. Tripawds blog, and a more detailed blog here. Please also check out my novel, What the Dog Ate. Now also in paperback! Purchase it at Amazon via Tripawds and help support Tripawds!

Member Since:
9 June 2012
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27 June 2012 - 9:27 am
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gunillas said

Sorry to hear this. I didn't know you could give chemo in tablets. I thought it only was given directly into the blood. Why have you been ordered tablets? Hope he will be better soon.

 

I saw now in another topic that you've written Zeus got IV chemo first. Than I understand. Sorry for missing this. Really hope he will feel better as soon as possible./Gunilla

San Diego, CA
Member Since:
29 October 2010
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27 June 2012 - 9:30 am
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Gunilla - if you want to learn more about the at-home chemo pills, it's usually referred to as "Metronomic Protocol" so you can search on that phrase. (It's called that because you give low-dose pills at home regularly, like a metronome.)

Abby: Aug 1, 2009 – Jan 10, 2012. Our beautiful rescue pup lived LARGE with osteosarcoma for 15 months – half her way-too-short life. I think our "halflistic" approach (mixing traditional meds + supplements) helped her thrive. (PM me for details. I'm happy to help.) She had lung mets for over a year. They took her from us in the end, but they cannot take her spirit! She will live forever in our hearts. She loved the beach and giving kisses and going to In-N-Out for a Flying Dutchman. Tripawds blog, and a more detailed blog here. Please also check out my novel, What the Dog Ate. Now also in paperback! Purchase it at Amazon via Tripawds and help support Tripawds!

Member Since:
9 June 2012
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9
27 June 2012 - 10:01 am
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AngelAbbysMom said
Gunilla - if you want to learn more about the at-home chemo pills, it's usually referred to as "Metronomic Protocol" so you can search on that phrase. (It's called that because you give low-dose pills at home regularly, like a metronome.)

Ok. Thank you Jackie!/Gunilla

On The Road


Member Since:
24 September 2009
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27 June 2012 - 11:11 am
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AngelAbbysMom said
Gunilla - if you want to learn more about the at-home chemo pills, it's usually referred to as "Metronomic Protocol" so you can search on that phrase. (It's called that because you give low-dose pills at home regularly, like a metronome.)

Here is a post with a lot of info for you:

Metronomic Therapy: Jerry's Experience & a compilation of other information 

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

Rock Hill, SC
Member Since:
28 November 2011
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11
27 June 2012 - 11:20 am
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Thanks everyone.  I came on into work this morning hoping that he would settle down and rest - he promptly threw up all over his pillow and crate.  I can't believe there was even anything left in his stomach.  I had already done two loads of laundry this morning before leaving for work (sheets, comforters, towels, you name it).  Guess I'll have some more to take home with me. what-ever

Thanks, Jerry for letting me know that the Peroxicam didn't agree with you.  I had searched the forums this morning before posting and I saw that other dogs took meds other than Perox, but I wasn't sure why.  Dr. Google also informed me that this can be a harsh med for some.  I gave him six pieces of kibble at lunch (literally) and so far so good...

Zeus was a Husky mix diagnosed with Osteosarcoma at age 11.  A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/

On The Road


Member Since:
24 September 2009
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12
27 June 2012 - 12:31 pm
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Yep, it made me hurl when I went on it for arthritis, long before my diagnosis. We switched to Meloxicam and that was that, my belly was fine afterward. Don't forget, you can get it in generic form and it's a LOT more affordable than the name brand version.

Feel better Zeus!

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

Mesa, AZ
Member Since:
27 April 2009
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13
27 June 2012 - 2:12 pm
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Sorry to hear Zeus is sick.  Don't know about metronomics , but do know that it's awful to throw up. 

Hope he feels better soon.

Chuy, showing everyone that Tripawds do everything 3 times better than regular dogs!

Chuy's Short Stories

Las Vegas, Nevada
Member Since:
14 August 2009
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14
27 June 2012 - 2:33 pm
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Poor baby Zeus!  I hate throwing up too!

 

I'd for sure would let his tummy rest like the vet said.  Maybe some brothy rice and chicken to help it and keep him hydrated.  (this is what my vet suggested when we had a bad bout of throw ups) Since he is throwing up that much you don't want him to get dehydrated.  

If it were me, I'd give pepcid (famotidine), instead of Prilosec. Prilo is a proton pump inhibitor and doesn't work as fast as an acid reducer like pepcid.  Keeping in  mind, three legged dogs having to hop, churns up the stomach acid and can hit the throat and make them throw up. I had it happen with comet on antibiotics....hop, hop, hop...throw up.  Even as a sufferer of acid reflux, I've thrown up when there is so much acid coming up into the throat.  (lovely, I know.)

 

Good thoughts coming his way.

Her Retired AvatarComet - 1999 to 2011

She departed us unexpectedly  January 23, 2011 at the age of 12 1/2.

She was born with a deformed front leg and a tripawd all of her life.

Linden, MI
Member Since:
11 November 2008
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15
27 June 2012 - 3:45 pm
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Nova didn't have stomach issues with Cytoxan/Piroxicam, but her oncologist had her take it with Pepcid.

 

Hope Zeus feels better soon!

Dane Mom Sue at nova.tripawds.com and Mom to Beautiful Great Dane Queen Nova, a Blind Tripawd, who kicked cancer's butt from 11/08-03/13. The Queen is Spirit Nova now, but her legacy lives on here at Tripawds!

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