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cemil's friend malachi-first chemo treatment today
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Winnipeg
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6 January 2010 - 8:26 pm
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What? Do you get them measured every day of the week?  Twisted Poor Oslo. It is amazing he has any blood left! It seems that Caira Sue is not the only vampire on this website!

I think Emily was also on a 25 day plan. (I bet Power Mushrooms would get them back up more quickly!)

Ft. Lauderdale, FL
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6 January 2010 - 11:45 pm
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Hi,

Yes, I was just going to start with one supplement and do that for a week to see how Mali does on it. Then add another and do that for a week. So then he'd be getting 2 supplements. But when he'd have a chemo treatment, I would withhold the supplements until day 8 or so or maybe all together if he is not feeling well.

I really would like to start him on the fish oil/DHA, MyCommunity from Fungi Perfect and the transfer factor plus. I can hold off on the other stuff to later on.

Yes, its Arteminisin (sp?) and I also have Artemax from hepalin. I'd give the Art-e in the morning (empty stomach) and then the artemax (contains the 3 type of formulations of art-e) at bedtime (at least 3 hours after a protein meal). I also have Denasyl (SAM-E) that I had been giving him prior to his surgery for liver support.

I received the fungi perfect MyCommunity pills today, but not the 4Life tranfer factor plus yet. I was told to give them both about the same time as they compliment each other.

I don't want to overload him with supplements. All Mali is getting right now is the cerenia and his last dose is tomorrow, unless he gets sick again.

Oh, he pooped tonight and it was pretty normal, so is a good thing.

We walked a bit tonight again .. he loves it cool out and 40* is cool to me and him. I offered him his shirt, but he wasn't interested. If he wanted it he would of put his head in the neck opening and then laid down so I could put his leg through the sleeve and then he'd get up for adjustments and off we'd go. But we went out, this time I had my jacket on as Don was in bed already, so no minivan option tonight if he got tired.

I guess one very small positive regarding Mali's amp surgery is that I can now go out the door with him off leash and not worry he'll take off running like a crazy dog .. Now he just hops out, urinates and then we walk and I let him hop off leash. He really enjoys that. Tonight he went up into the neighbors yard and laid down near the house and hedge .. out of the wind. So we were already 2 houses away and I told him okay .. rest and Oz and I are just going to go to the next light pole down the street. I stayed in the middle of the road .. side neighborhood street with next to no traffic and no at around midnight anyway and walked backward .. looking to see if Mali decided to follow us and then checking on Oz who is only about 5 -6 ft ahead of me pee-ing on every tree possible he comes across in the swales. Yep .. sure enough, I see Mali coming around the car parked over the sidewalk and I start walking towards him .. I was only 1 house away from him and told him lets go quick quick back home. He turned around and head home and then stopped to rest at the same place he was before. Oz and I waited 10 minutes and then he was ready again. We made it to the next house and he rested for a few moments and then he went the rest of the way home without stopping. He is now sleeping on his big bed on the living room floor. Sam and Moe are each sleeping with their heads on the bed to be near Mali. Mali doesn't like his personal space infringed upon .. so this is as close as they can get to cuddling with him. Even as a 8 week old puppy, he didn't like his littermates to share his space. 🙂 Only time he allows exceptions to this rule is during car trips where someone is usually touching someone else as the suburban is only so big, same with the minivan and 5 Anatolians take up all the empty space (luckily we usually only have 1 suitcase and cosmetic bag or depending on where we are going, I will ship some stuff prior to our arrival - like visiting my parents in Toronto or family in MA). The other dogs have be great with him. They will readily give up their bed so he can have it and try to stay out of his way. I guess they know something is very different as they don't jump on him or get in his way when he move about the house or yard. Even the cats are pretty understanding and he'll let them lay near him .. still not next to him though. Even I can't lay right next to him - if I do for more than just a few minutes, he'll grump and either start to move so I keep moving over until I'm off the bed or he'll push with his feet against me until I get off his bed. However, he is fine with me sleeping on the couch right next to him. Oz has no such problems and will curl up with you .. a spoony and same with Sam and Moe. Gabby likes her space too, but she doesn't care if someone sleeps curled up next to her and rests their head on her back.

Mali is not going to have another blood test until he goes in for the 2nd chemo treatment on 1/26. I guess if his levels are not good, then the chemo will be postponed, but he goes every 3 weeks (so 21 days between treatments).

Monday I start school again full time .. meaning monday, wed & fri I classes from 10;30 - 2:30; monday night from 6 - 8 pm and thursday night 6 -8 pm. Don will be home with Mali when I have the evening classes, but he'll home alone for 4 hours on M, W, & F. I think he'll be okay though. I have no school on tuesdays so that is when I scheduled his chemo treatments at 9:00 am so if he gets sick a few hours later, I'll be with him. I just hope he doesn't get that sick again.

Everyone is sleeping now and I just gave Mali some water and now he is back asleep. I guess I should go to bed and get some rest. Since his dx of OS, I have just been unable to sleep and stay up watching him. I will have to get back on a schedule for school though.

Thanks again for all the good thoughts and wishes for Mali.

Christine

My heart lives at Rainbow Bridge
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7 January 2010 - 4:01 am
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Thanks for the smile, Christine.  Reading about your crew and how different they are put a smile in my heart.  Sounds like Mali is going great.  I'm sure 4 hours during the day will be Ok to leave him alone.  They need their rest anyway.

I can so relate to you being awake watching him.  I did the same thing with Trouble.  Lucky for me, I have a bunch of insomniac friends.  They would catch me on the compute r in the wee hours of the morning, give me a pep talk, and send me to bed. For me it was like my brain just wouldn't stop.

It is good you can't sleep next to Mali.  I spent untold hours laying on the floor beside Trouble. Looking back, and knowing how important rest can be, that really wasn't a good thing. lol

Shanna & Spirit Trouble ~ Trouble gained her wings 3/16/2011, a 27 1/2 month cancer survivor, tail wagging. RIP sweetheart, you are my heart and soul.  Run free at Rainbow Bridge.
The November Five - Spirits Max, Cherry, Tika, Trouble & Nova. 11/2008 - 3/2013 An era ends as Queen Nova crossed the Bridge.

Winnipeg
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7 January 2010 - 8:31 am
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Enjoy yourself now, Christine. Before long, Mali will dash out the door to take off to say hi to all his friends.

Once he is on fish oil and Co10Q (sp?), there should be no reason to stop them during chemo, unless fish oil gives him the runs like it did with Tazzie (only a bit soft, not really runny). The heart enzyme (C010Q) is probably good to get started to protect his heart, given his size. What about glucosamine chondroiton? Most of us use that because of the extra stress to the joints.

Okay, so you know you cannot give Artemisinin within a few hours of protein. I did not know you could give "Art-e" (I don't even know which part of Artemisinin that is) in the morning, close to a protein meal. Pam and I gave the Artemisinin drugs before bed 3-4 hours after our dogs ate. We also started Artemisinin after chemo, but I don't know if that matters. There is a lot of material in the archives about Artemisinin , submitted mostly by Pam around November of 2008 and me this autumn (Sept-Oct). Cuoto at Ohio State Univ uses it on greyhounds - so we could check to see whether he uses it during regular chemo or starts it after the chemo ends. I remember seeing that information on a newsletter on that greyhound program. (One thing that does matter, which is irrelevant to you now, is to avoid using Artemisinin during radiation therapy.) I would definitely mention the Artemisinin to your oncologist. It is a drug/supplement that most oncologists don't really seem to like, although generally they say it does not seem to cause harm or interfere with things.

I used Power Mushrooms, which really seemed to BOOST Tazzie's energy. But your fungi supplement might have a similar effect. Then again, I don't know what an oncologist's opinion is about boosting the immune system during chemo. Even if it makes the dog feel good, does that help or hurt the chemo try to kill the cancer cells (I don't think I ever heard this question really discussed).

I did not mean to underplay the effects of Carboplatin in my earlier emails. Although most dogs seem to have cruised through Carbo chemo, I think Oslo has suffered some infections following low blood counts following Carbo. He is a newfie, so similar in size to you. You might want to check with him.

40 degrees cool? Well, yes, in a way. It is -40 here today and it is cool.

Ft. Lauderdale, FL
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7 January 2010 - 9:30 am
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Yes, in Ft. Lauderdale, anything below 70* is considered 'cold'. I'm from Toronto and -25 or lower (does it even matter at that point?) is fine with me. Usually when its cold, its beautiful outside. Now it nice and sunny here .. I love this weather when it finally arrives in S. FL, but give me snow and the seasons any day and I'd be very happy. I'm walking around in just jeans and tshirt and everyone else are wearing parkas - they are crazy. 🙂

I just spoke to the oncologist's nurse .. I'm getting miffed now. I asked for cerenia, but they said that you have wait 3 days before giving cerenia again. Today was Mali's last day on his cerenia .. so that would be Sunday or Monday before he could start it again and it has to be continued for 4 days. Okay .. fine, but give me something in case he gets nauseous again. So she said they could call in a prescription to my drug store for something - she didn't say what med - but it was $300 for the script. Then she said they have it at their office in injectable form, but didn't think I'd want that since I'd have to give him a shot. Yeah, so - I've given loads of shots to my guys - SQ and IM. Gabby gets adequan shots IM and I give allergy shots to Sam (SQ), plus I've given fluids to my cats that had cancer and when Gabby was a puppy gave her SQ fluids too when she had erlicha and was vomiting / diarreha. I said I have no problems with IM or SQ shots, and the nurse blew me off. (!!!!) Now she said they have something else Mali can take .. starts with an "m" .. met... something .. she said it too fast, but its inexpensive and I can pick it up later today from their office. Whatever, but it better work.

So how do you deal with a dr./nurse who think pet owners are clueless?? Basically, right now, I'd like to go put my foot up her butt, but I don't think that would be in Mali's best interest. I could call my regular vet and ask her to speak to the onc and that she better change her attitude when speaking with me. It just ticks me off .. I do like the oncologist, but if this continues I might take Mali elsewhere, but I hate to do that to him as he likes it there and he is not very trusting of people he doesn't know, so I would not want to add more stress to the chemo treatments.

Just frustrating.

Winnipeg
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7 January 2010 - 9:47 am
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I don't know why, but I was also told that Cerenia can only be given for 5 days in a row (or one shot, then four days of pills). But that is usually sufficient to get dogs past the nausea stage. I was told that I only had to break it for one day and could begin again. But I did not need to start it again. I was never told that I had to continue for four days, only that I could go that long. Does Mali show any behaviours that lead you to think she is feeling or likely to feel nauseas (sp)?

Ft. Lauderdale, FL
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7 January 2010 - 10:12 am
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This morning he only ate a little of his vanilla yogurt and he turned his head away like it was making him sick. I asked him to try to eat a little more and then he got up to move to another location, so I took the dish away and he settled down. Usually he likes his yogurt but not today .. its the same vanilla goat milk yogurt he's been getting .. nothing different and I add the Jarrow brand probotics to it. I even tried to give him some without the probotic powder added .. nope, he was not interested. I know pre-amp/chemo sometimes he would not want anything in the morning, but since the surgery he's been having his yogurt. 🙁

I looked up the med that the nurse is going to have ready for Mali - its Reglan (sp?). Why can't people just say the brand name so I don't have to look up meds??? I'm still ticked at her. I told my husband and he said that once she gets to know you she'll realize you are not a clueless pet owner. She better or we are going to have some issues.

Per Pfizer's protocol on cerenia it is to be given 5 days, then stop for day 6, and can be resumed again on day 7. It also said it can be given for 5 days in a row .. not - must be given. Hmmm ... time to question the dr./nurse again. Grrrrrr....

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7 January 2010 - 10:37 am
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Hi Christine,

Before I forget, Tazzie's Mom Susan is right.  Emily did have to have her chemo every 25 days because of low blood counts.  Other than that she sailed through the chemo.  Our oncologist gave her Pepsid.  I don't know if she would have gotten nauseaus or not.  This is the same pepsid people take.  She took one tablet a day for five days after her chemo.

I am sorry that you are having problems with your oncologist.  I don't know if it would work for you but maybe if you asked things in a question instead of stating what you want your oncologist would be more cooperative.  Maybe like, I heard that ----- works well for nausea and I was thinking I'd like to use that.  What do you think?" That way if there is an ego at work maybe you would be stroking it and not, what she/he might see as questioning her decisions.  I know it is stupid but some people are like that.    I used to have to tell my old boss that I had been thinking about her decision and I decided I wanted to do it.  Thing is she never suggested it or vetoed by idea but she would forget and when I gave her credit for it then she liked it.

Glad to hear Mali is doing well.  Don't worry, you wont be able to keep him of the leash long!

Debra & Angel Emily

Debra & Emily, a five year old doberman mix, who was diagnosed with an osteosaecoma. She had a right rear leg amputation on May 19, 2009. On November 10, 2009 she earned her wings and regained her fourth leg.


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7 January 2010 - 10:56 am
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I am glad that Mali is feeling better.  Cerenia is only labelled for oral use for 5 days after the injection although in certain cases I have used it longer than that but usually it is not needed.  My Dogue de Bordeaux takes Reglan (metoclopramide) twice daily every day for a GI motility problem and that drug is very safe and inexpensive.  Most dogs only experience nausea for a few days post-chemo.  The bone marrow suppression thing can happen anytime and does seem to vary depending on the dog.  My Mastiff Tazzie always had a low platelet count but her white cells remained okay so we kept to the 21-day plan as best we could. In general as long as the neutrophil count (a type of white blood cell) is at least 2000 the chemo can be given.

As far as supplements go my dog took SAM-E for her liver as well as fish oil and Dasuquin from day one.  I did not start the artemisinin until her chemo was finished on the advice of my oncologist but I do not think it would hurt.  I just wanted to get her through the possible side effects of the chemo before I started anything new.  I also tried metronomic chemo after the fifth carboplatin injection but had to stop after 6 weeks due to side effects (bladder infections).

I do wish that I had started the Power Mushrooms sooner.  I thought the K9 Immunity was way too pricey for the number of capsules I would have to give my big girl but then my holistic vet recommended the Power Mushroom brand and I was very happy with both the price and the positive energy that Tazzie had after she started taking them.

Good luck with your big boy and please post photos soon!

Pam

PS Susan may still have some artemisinin from both of our dogs (both named Tazzie) unless it has already been donated to somebody else.

Ft. Lauderdale, FL
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7 January 2010 - 11:17 am
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Hi Pam and Debra,

Yeah, I do sorta ask for stuff with the oncologist, but the nurse I do not. Or I'll ask if she can check if that is okay with the oncologist.

I have no issues with giving Reglan .. I've used it before personally and with my cats and even with Gabby. I also have pepcid and will give pepcid if someone is feeling a little off.

I will start Mali with the fish oil and continue with his SAM-E (which I know did not have any side effects pre surgery or post surgery). After Mali is okay on the fish oil / SAM-E for a few days, I'll add his mushroom caps.

I can wait on the artemisinin till after his chemo treatments .. not a problem to wait. I'm also posponing his rehab until a week after his 2nd chemo treatment .. just want to see how he does with this and where he's white cell counts are going into the 2nd round of chemo.

For joint supplements, I have a brand called liquid health ..level 5000 that I give to the dogs in their food. It contains: 5200 mg of Glucosamine per ounce, plus MSM, Perna, and Shark Cartilage. Level 5000 also includes several powerful antioxidants such as Ester-C and Grape Seed extract, digestive enzymes, as well as Cat's Claw (an herb) and Manganese to enhance it's benefits. I usually pour about an ounce into their food as I'm mixing up their dinner.

I'll try to post some pre surgery pictures of Mali. I did take some pictures of him post surgery, but they are still on the mem card in the camera. (I'm a bad mom when it comes to taking pictures .. as that I don't or do, but leave them in the camera way too long. Plus when I went to use the digital camera post surgery, the LCD screen is all screwed up .. so I hope the pictures are not distorted. I think Don may have dropped the camera. I'll have to get a new one eventually .. things are expensive now since being laid off last February.)

Ft. Lauderdale, FL
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7 January 2010 - 11:24 am
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How do you post pictures so they show up in your profile picture?

Winnipeg
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7 January 2010 - 11:46 am
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Good to hear from Pam – (in case you don't know, Mali, tazziedog Pam is a vet and gives the most reliable advice and info)

I did post the Artemisinin on the 'angel exchange' last night. Let me know if you want it (same goes for anyone else). I was not suggesting to wait to start Artemisinin , just to look into the timing. Pam can probably advise on that. I know the same question has come up before.

Pepcid might be a good thing to try. But I know there is at least one drug that conflicts with Pepcid. Maybe Artemisinin ? Maybe Cytoxan? There was something Tazzie was on and at the time my vet said to avoid pepcid. This is why it is good for your vet & oncologist to know what supplements you are taking.

Fortiflora is another thing that might help the GI system. Can get it from your vet and give a couple times per week to help the 'friendly microbes' coat his stomach.

Originally I gave K9 immunity to my Tazzie. When I ran out, I started with Power Mushrooms, which happen to be much cheaper. Boy did I see the difference with the latter! But it will be interesting to hear from others to know if they see a difference.

On The Road


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7 January 2010 - 12:33 pm
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chrisk101 said:

How do you post pictures so they show up in your profile picture?


Simply follow these instructions for uploading your user profile avatar.

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

Livermore CA
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7 January 2010 - 8:11 pm
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Hi Christine

I've been following Mali's story–just haven't had a chance to post for a few days.  Sounds like you're a Super Mom and he's doing fine.  I have camera issues too (can't seem to keep the battery from draining down), but I'll have to get them resolved so I can put pictures on Cemil's blog.

I'm glad to hear Mali's success stories and I'm astounded that you can fit five Anatolians in the back of your Suburban.  They must get along really well–or else it's really a Mack truck and you just call it a Suburban. Laugh

Mary and Cemil

Cemil and mom Mary, Mujde and Radzi….appreciating and enjoying Today

Cemil's blog

Ft. Lauderdale, FL
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7 January 2010 - 11:21 pm
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Hi Mary!

LoL .. no, its a suburban. Yes .. everyone makes allowances for the ride. Only one that takes a while to settle down is Moe as he wants to look out every window and OZ and Mali like to both be right behind the driver's seat .. and Oz usually jumps in first and claims the spot .. so it Oz/Mal and then Gabby make up group that is right behind us. You hear some growls when Moe tries to get into that space as its pretty well taken with just Mali and Gabby and Moe will step on someone and doesn't care the he did either.

Its even funnier when we go away in the minivan ... that is pretty tight and Gabby will be so close to Oz or Mali that her head has to rest on someone's back or side depending on if they are laying down or sitting up (in the minivan, Mali always sits up or he can't see out the windows).

Mali seems restless tonight .. like he can't get comfortable. He ate his dinner .. cooked chicken and green tripe and went out to urinate and sat in the yard for a little bit, but I brought him in as its getting cool tonight and he didn't want his shirt on. I just gave him a tramadol, pepcid and 2 phazymes. I hope he's okay. Then chester the cat walked by him and must to brushed against Mali's foot as Mali awoke startled and tried to jump up, but kinda fell over on his side as he must of forgot that his left front leg is gone. Mali is on the twin bed mattress so its not like he fell on something hard .. actually he didn't really fall as he didn't get up, just sat up and would have got up but couldn't, so I guess he tipped over some. I tried not to go run over to him or make a big deal about it, but it's hard not to get upset.

It's been about 15 - 30 minutes since I gave him the tramadol and he is still a bit restless. He moved off the twin bed .. it's long enough but not wide enough and has coil springs instead of mem foam. Gabby is on his favorite bed, so he is now on the smaller memory foam bed .. 54 x 42 .. still 8" high of mem foam and has the plushy cover. Maybe it was just the twin bed being uncomfortable that was bothering him. He drank more water too. Does chemo make them thirsty? Mali slept most of the day, so maybe he's water intake was low today.

I did pick up the reglan for Mali today from the onc's office. They asked how Mali was doing so I said he seems okay and they just said its pretty common for them to be extremely tired now for a few days after chemo. I hope that is all that is going on, but why so restless? No temperature .. nothing else out of the ordinary .. 🙁

Mali seems to be a little more comfortable on the mem foam bed. I gave him 2 voortman coconut cookies .. he loves them and he ate them. Mali hasn't wanted the vanilla oreos since the surgery, which he usually likes too. So I picked up some of the coconut cookies for him yesterday while shopping.

I hope Mali settles in or it will be a long night of watching him.

Something else I noticed .. Mali will drink some water out of the water bucket outside and then come over and just lean up against me. Anatolians do lean against people, but now he is really leaning on me. Plus if I go into the house, he'll come with me and lay on the big bed next to the couch were I usually sit. If I walk into the yard, he'll come with me too and lay down and wait till I'm done with whatever I might be doing and then he'll get up and either lean against me in the yard and then follow me into the house. Its not like he's being clingy as he is not that kind of dog, but him following me while out in the back yard is new.

I just finished giving him a massage on the right side shoulder area and neck and chest and right leg/side. He was a bit tight, so maybe he has muscle fatigue. It makes sense that can happen as he is probably doing much more with his right side muscles then before the surgery.

It's hard and gets depressing .. don't know what to expect and what is normal or not - other than the obvious when he is sick.

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