Just came across these two interesting trials going on:

Compassionate Use of TTG100 in Canine Cancer

Current Status: Active and enrolling
Principal Investigator: Mike Henson, DVM, PhD, DACVIM
Contacts:
Dr. Henson: henso001@umn.edu
Amber Winter, study technician: 612-624-1352 or alwinter@umn.edu
Oncology service at 612-626-8387 (main VMC number) 

TTG100 is a new drug in a class of drugs which may be effective against a variety of types of cancer in dogs. In particular, we are seeking Bernese Mountain dogs and Golden Retrievers with histiocytic sarcoma. We may be able to treat other breeds and other cancers as well. The study involves an oral drug given at home, with five visits to the Veterinary Medical Center over a 3-4 month period.

Owners will be responsible for the costs of the visits. However, thanks to our generous donors, we can offer a $1,000 credit to owners to help with costs, paid as $500 at enrollment and $500 at the conclusion of the study.

Hypoxyprobe study (Bone Biopsy)

Current Status: Active and enrolling
Principal Investigator: Sara Fritz, DVM
Contacts:
Dr. Sara Fritz: 612-626-4333 or sefritz@umn.edu
Amber Winter, study technician: 612-624-1352 or alwinter@umn.edu
Oncology service at 612-626-8387 (main VMC number)

This pilot study will use a new technique to visualize hypoxic, or low oxygen, areas of a bone biopsy taken from dogs with suspected osteosarcoma (OSA). Oxygen gradients exist in normal and tumor tissue. These gradients affect the cells at the genetic level and are important in normal and abnormal conditions. Until recently it was difficult to measure these gradients at the cellular level but Hypoxyprobe-1 (pimonidazole HCL) has made this possible. If scientists can understand these areas in tumors they may be able to develop treatments for  these tumors in the future.

We are looking for dogs scheduled to have a bone biopsy at the Veterinary Medical Center (VMC). Owners who consent to this study will bring their dog the day before the biopsy to receive one intravenous (IV) treatment of Hypoxyprobe-1. Dogs will stay overnight for observation.

The study will cover the cost of the hypoxyprobe and the overnight stay in the hospital.