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Possible ulcer/intestinal bleed - watery mouth?
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Madison, WI
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14 June 2009
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1 October 2009 - 9:58 pm
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So Wednesday night Yoda had to be seen because he didn't keep his food down pretty much all day.  He had just been in last Friday for a bloody cough, when they believe they found a ruptured lung met.  Just in case, however, since Yoda has been on Piroxicam and it was possible the bloody cough was from intestinal bleeding from the Piroxicam, in addition to more pain meds, she had me put Yoda on 15 mg of Pepcid twice a day.  So he's been on that since Friday or Saturday.  His stool turned black for a couple days starting Saturday or Sunday, which she told me to expect, because he was likely swallowing blood not just coughing it up.  But after a couple days his stool went back to a dark brown.  Wednesday afternoon, after the vomiting began in the morning, his stool had turned black again. 

Originally, I wasn't worried when Yoda threw up his breakfast, because his energy was up and after I gave him breakfast a second time he kept it down for several hours.  I knew not to give him anymore Piroxicam and I e-mailed the oncologist initially and figured I'd call if he threw up again.  She e-mailed back that Yoda may need to go on sucralifate, but that it was good he still had an appetite and was feeling well.  Later that evening though (after hours), after I gave him dinner it looked like both breakfast and dinner came back up.

So I took Yoda in to be seen and the vet on duty prescribed Cerenia and they gave Yoda an injection of it while we were there.  He didn't suggest sucralifate and I let it pass.  Wish I hadn't.  I called Yoda's oncologist the next day and she wanted him on that too.  So we added that this evening.

So Yoda, since last Friday, has been on Tramadol, Tylenol/Codeine, and Pepcid, started Cerenia last night, and sucralifate this evening.  His appetite has been mostly good.  He ate his breakfast and almost all of his dinner (left a little behind, which is a little strange).  He was a little fussy about taking his pills throughout the day, but didn't ultimately refuse until his final dose of painkillers tonight.  I did eventually get him to take them in butter as a last resort (thanks for the tip Jack & Jack's mom!).

Anyway that's a lot of background for what I know may be nothing at all…

Tonight I noticed Yoda had drops of water falling from his mouth, as if he had just been drinking water from his bowl, but I knew he hadn't and it has continued for quite a while now.  So I did call the vet clinic's emergency line for my piece of mind, hoping to rule out that this was an additional sign of an ulcer or something like that.  They weren't really sure and mostly just kept asking me about his appetite, which I told them only recently seemed a little off with taking his pills (in meaty wet food, which usually does the trick).  They were also concerned because I wasn't 100% certain Yoda hadn't vomited, because he had gone out in the yard several times tonight.  He's been anxious to hunt wabbits all night.  Maybe that's what all the drool is about?  But he's gotten excited about rabbits plenty of times before without his mouth watering so dramatically.  He definitely didn't catch any – I was careful to make lots of warning sounds each time I left him out and hung around long enough after I let him loose to be sure none had hung around.  I have since been able to search the yard with a flashlight and no sign of vomit or dead bunnies.

There I go again – probably way more info than necessary.  I'm just wondering, because the vet tech didn't really say either way, does the water dripping from the mouth indicate anything related to an ulcer or nausea, etc.?

I'll be in touch with Yoda's oncologist tomorrow morning.  The vet tech had said that if Yoda's apparent nausea continues, he may need to be admitted to be given drugs intravenously.  I really hope it doesn't come to that.

By the way, his gums have been pale for maybe a couple weeks now, but when I noticed the dripping, I checked his mouth and they looked their normal pink again!  Good sign?

Yoda liked the taste of his sucralifate slurpy (or whatever the pharmacist called it – the pill disolved in water).  Weird?  It took forever for him to let me get any of it squirted into his mouth initially, and some got wasted, but then it turned out he really liked it and wanted more.  Too bad I couldn't get him to notice the drops on the floor and lick those up.

Thanks for reading/skimming this novel.  Sorry if it's silly to worry about a watery mouth.

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide

Madison, WI
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2 October 2009 - 4:36 am
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I probably have three hours to kill before I'll likely hear from Yoda's oncologist, so I figured updating how he's doing would keep me busy...

The watery mouth has continued this morning and it seems his lack of appetite/nausea is holding steady if not increasing.  He didn't like his sucralifate slurry this morning.  Still seemed interested in the taste, but decided just a taste was enough and then fought and fought to keep me from squirting it in.  It stressed the both of us out a lot.  I think I may have gotten half in him, when I finally had to throw in the towel and put half of another tablet into some butter.  That worked again, but am afraid maybe the butter isn't good for the state of his stomach and will cancel out the good effect of the sucralifate?  Also had to give him his Pepcid in butter.  I tried a new wet food flavor on him (fish this time), since he turned his nose up at two others last night, but he didn't want anything to do with it.

He was strangely anxious to get out and walk - and to look for bunnies in the backyard.  This is weird for him so early in the morning.  (I've been trying to get him used to getting up early for walks since my work schedule will change dramatically next week - we usually sleep in til 9 am or later, I've been working on getting us up by 6 am, but this morning he was whining to go out at 4 am!).  He started to try and chomp down some grass on our walk, but I didn't let him - couldn't let the medicines I finally got in him come back up!  On his walk, his stool was loose, but not full-blown diarrhea, and not black at all this time, if that's a positive sign.

I'm preparing myself to hear from his oncologist that they have to keep him there for a day or so, like the vet tech said last night. Frown

He's gone back to sleep.  Looks comfy on the couch.  But it's time for his painkillers.  Cross your paws...

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide

Michigan
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31 August 2009
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2 October 2009 - 5:10 am
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If Rocky had 2 paws to cross for Yoda, he would. Well technically, I guess he could cross his back paws. Yeah, that's what he'll do!

Wishing you good news when you hear from his oncologist today.

I smile each and every time I see Yoda's picture.  Smile He's a cutie.

Michelle

Winnipeg
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13 July 2009
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2 October 2009 - 7:09 am
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Yikers! I didn't see all this coming when I turned off the e-box last night.

In contrast to some of us, I'd say you are surprisingly relaxed. Is the bleeding or possible ulcer under control? Is that what the sulf. drug is for? Can one dog really so many different forms of medicine? (as long as they are coated with butter)

Tazzie

Madison, WI
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14 June 2009
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2 October 2009 - 9:21 am
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Yoda's doc said that some dogs actually get nauseaus from the Sulf. and that we'd better take him off of it and he should improve with just the Pepcid and Cerenia.  The timing with when he started getting real fussy about taking his meds fits that theory that it was the Sulf.  He should improve in the next 24 hours.  If he were to vomit or get worse in anyway, I'm to bring him in and he'll probably get a couple injections for nausea.  Phew!

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide


Member Since:
22 August 2008
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2 October 2009 - 11:55 am
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Nausea could be due to the ulcer or due to Carafate (sucralfate).  I find that it works just as well if you give the pill (1 gram) orally without making it into a slurry. If this was my dog I would have him on Carafate 1 tablet 3 times daily (heals ulceration) as well as Pepcid 20 mg twice daily (antacid).  When Kona ulcerated from Deramaxx I also gave her Prilosec 1 pill daily.  We did all of that for 2 weeks.  If your dog is vomiting then Cerenia daily is also a good idea.

There is no good way to test for an ulcer without endoscopy but I would strongly suspect one since he was taking Piroxicam. If an ulcer perforates it can be deadly or require surgery so I would strongly suggest going back to the Carafate.  If he had pale gums and black stool that could be either from the lung met or intestinal/gastric ulceration.

Hope he feels better soon!

Pam

Wesley Chapel, FL
Member Since:
13 September 2009
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2 October 2009 - 5:22 pm
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Jake also started vomiting a few days after starting on his Previcox and Tramadol after he broke his leg and then had his bone biopsy... But my vet had me start him on pepcid AC and after a day or two, that really did the trick. If that didn't work, he was going to put Jake on Carafate also, but it never came to that. Then, since his amputation... he was only on Tramadol and antibiotics... and never had any problems with those.

You should probably also learn (ask your vet or vet tech for a demonstration) how to give Yoda's meds directly down his throat... and not always drenched in butter and stuff. That may also be helping to upset Yoda's sensitive tummy... I would always try to give my meds with some peanut butter first, but if Jake ever spit them out, then I would just go in and put them down his throat... The drooling you see with Yoda can be due to nausea and/or some of his medications...

Poor baby... Hope that Yoda feels better real soon...

Jake, 10yr old golden retriever (fractured his front right leg on 9/1, bone biopsy revealed osteosarcoma on 9/10, amputation on 9/17) and his family Marguerite, Jacques and Wolfie, 5yr old german shepherd and the newest addition to the family, Nala, a 7mth old Bengal mix kittie. Jake lost his battle on 11/9/2009, almost 8 weeks after his surgery. We will never forget our sweet golden angel… http://jakesjou.....ipawds.com ….. CANCER SUCKS!

Oregon
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19 September 2009
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2 October 2009 - 8:50 pm
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I wish I had something positive to offer... We hope that Yoda feels better really soon!!!! Keeping our paws crossed and sending hugs your way...

Shilo diagnosed with osteosarcoma 9/4/2009, amputation 9/9/2009. ShiloAnne lost her battle 11/23/2009 where she regained her fourth leg and is patiently waiting for her parents to join her. We will always love you baby girl.

Madison, WI
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14 June 2009
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2 October 2009 - 11:00 pm
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Hey Pam,

Yoda has been on the Cerenia daily.  He resists (violently) the sucralifate now both as a slurry and as a pill (because he's resisting all pills at the moment).  And he has and continues to be on 15 mg of Pepcid 2x a day.  He hasn't vomited since he's been on the Cerenia.  I'd certainly be tragically stuck, financially, if Yoda needed surgery for a perforated ulcer, but at the same time, his oncologist believes that the sucralifate he took actually contributed to his nausea and it's been a huge struggle to get him to take his pills since that started.  So, I'm pretty torn on your suggestion to put him back on the sucralfate (Carafate).  My understanding is that his oncologist thinks the Pepcid and Cerenia will be enough (though initially she seemed concerned when I told her the emergency vet didn't prescribe the sucralfate), since he is no longer vomiting and he has some appetite. 

He did have pale gums and black stool, but currently both are still past tense – is that a good sign that if they were related to the ulcer, that it is healing?

Thanks for your opinon thus far, just hoping to clarify a little.

Oh and could you tell me what kind of symptoms I'd see if it perforated?  His oncologist didn't bring up that possibility.

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide


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3 October 2009 - 12:45 pm
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Carafate is usually pretty standard to treat an ulcer because it actually coats the GI tract and adheres to the ulcerated area kind of like a bandage.  If he is doing well on Cerenia and Pepcid then he could still heal it just takes longer.  Sometimes I will add metronidazole as well (intestinal antibiotic).

The only way to know if he is getting better is to monitor his stool or gums and maybe recheck his red cell count and total protein (blood tests).  A dog who perforates often has a fever and is very sick!

Pam

Madison, WI
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14 June 2009
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3 October 2009 - 10:32 pm
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Thanks again, Pam Big Grin

Yoda has lost his appetite for anything, except treats now.  So I'm thinking, as long as he doesn't want to eat any way, I'm out of reasons not to put him back on the Carafate, right?  It's his last day of the Cerenia pill.  Unless he eats his breakfast tomorrow, I expect I'll be taking him in for an emergency visit - again.  His oncologist had said if he got worse (his appetite decreasing, I think constitutes as worse, though she used vomiting as her example) that she would recommend another Cerenia injection along with another anti-nausea drug injection that started with a "d".  I even wrote it down so I wouldn't forget, but now I can't find the paper. 

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide


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4 October 2009 - 10:29 am
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I personally would give him the Carafate since it can't hurt and may be what he needs.  Usually dogs do not get nausea from it unless it is given in a slurry so just try giving the pill and maybe follow with a syringe (about 3cc) of water if he is not drinking. He may need IV fluids as well as IV meds like Pepcid, Reglan, and ampicillin or metronidazole.

Pam

Madison, WI
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14 June 2009
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4 October 2009 - 1:43 pm
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Today I tried giving Yoda chicken with rice (mixed with his food) and found that he's pefectly happy eating as much as of that as he can get but he will eat as little of his dry dog food as possible.  He also loved some wet food made from rabbit and smearing that on his dry food got him to eat some, but the necessary ratio of rabbit meat to kibble for him to eat it was too high for me to give him very much that way.

I'm beginning to wonder whether this is still nausea affecting his appetite or if it could be pain related instead?  He was taken off the Piroxicam when he started vomiting, of course, and won't be going back on it.  No new pain killer was added to replace that, but when I got a refill of his Tramadol the other day, I saw his oncologist did up his dose of that from 1 tablet to 1 1/2.  Not eating his dry food would be the only symptom of pain that I can see, if that's what it is.  He hasn't shown any difficulty or reluctance getting around.  He played enthusiastically with a new stuffed ball I bought him.  His mouth has stopped watering though (so far).  The vet or vet tech I spoke to on the phone today said since the mouth watering was a sign of nausea, he's probably getting better and feeling less queasy (or not at all?).  She advised me not to bring him in yet, if a decreased appetite was his only symptom, but to give Yoda some more time and call his oncologist tomorrow.

His gums are still pink and no black in the minimal amount of stool he has left behind.

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide


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5 October 2009 - 11:28 am
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It sounds like he is getting better, especially if he is eating.  It is possible that he could have some pain, although usually it can be localized.  Tramadol can cause some dogs to have a reduced appetite but 1 1/2 tabs is not a very high dose.  I would keep him on the cooked food and Pepcid/Carafate and also continue the Tramadol.  If you never started the Carafate and he is feeling better then just hold on to it for now.

He also could have a reduced appetite because of the lung mets.

Pam

Madison, WI
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14 June 2009
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5 October 2009 - 8:48 pm
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He just keeps going back and forth.  Last night he started salivating heavily again and refused some wet food that he usually likes.  They gave him an injection of Odansetron (that's funney I thought it started with a "d") and then I got the pill version of Odansetron for Yoda today as well, because though the injection seemed to help, he was salivating and refusing boiled chicken the next morning.

I am experimenting with taking Yoda off the Pepcid, since apparently that too can cause nausea, and now he has the other med.  Plus, Yoda's oncologist doesn't believe we're dealing with an ulcer anymore, since there hasn't been any more melena (black stool).  She has concluded that the lack of appetite/watery mouth (nausea) is an effect of the cancer itself and he may just continue to decline.

Today he has eaten pretty well - some chicken and rice and some hamburger and rice.  A few of his treats still appeal to him.  He's turning up his nose at all his wet food, even when I make it as obvious as possible that there are no pills in it.

He's still active, doesn't seem to be in pain.  Though when we visited the park today, he didn't try to run with the other dogs.  He greeted them, enjoyed himself, but spent most of his time just investigating smells.  Once we got home though, he played more energetically with his new stuffed ball. 

Yoda&Mom united: 9/5/06 …….… Yoda&Leg separated: 6/5/09……… Yoda&Leg reunited: 10/14/09 ……… ……………….………….………….……. Yoda&Mom NEVER separated! …………………….….……....….…… Though Spirit Yoda currently free-lances as a rabbit hunting instructor for tripawds nationwide

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