Caring for a Three Legged Dog or Cat
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18 November 2022
Hi - hoping someone can give me some insight... our GP vet is out of his depth and was informed by our oncologist to consult him prior to any treatment; but our Oncologist (one of 3 in my province) is not in the office this week because they're moving facilities... cue my panic.
Boone is a neutered 5 year old mastiff x; diagnosed with osteosarcoma Nov. 17th; received 27Gy SRS treatments (9x3) Dec. 12-15; received biphosphinate infusion Dec. 16; started carboplatin (498.9mg IV) on Dec. 28th; 10 days post CBC showed low neutrophils (2.3); adequate platelets (103). Received second dose of carboplatin (498.9mg IV) on Jan. 18th; CBC that day indicated Grade I neutropenia (2.42); adequate platelets (187).
Follow up CBC on day 14 post 2nd chemo administration had the following results:
RBC 7.1 5.4 - 8.7 x10E12/L
Hematocrit 0.46 0.38 - 0.57 L/L
Hemoglobin 160 134 - 207 g/L
MCV 64.8 59.0 - 76.0 fL
MCH 22.5 21.9 - 26.1 pg
MCHC 347.8 326.0 - 392.0 g/L
RDW 13.9 10.0 - 19.0
% Reticulocyte 0.2 %
10.0 - 110.0
Reticulocyte 24.5 - 31.8 pg
WBC 5.9 4.9 - 17.6 x10E9/L
% Neutrophils 59.8 %
% Lymphocytes 19.8 %
% Monocytes 0.7 %
% Eosinophils 19.5 %
% Basophils 0.2 %
Neutrophils 3.5 2.9 - 12.7 x10E9/L
Lymphocytes 1.2 1.1 - 5.0 x10E9/L
Monocytes 0.0 0.0 - 1.2 x10E9/L
Eosinophils 1.2 0.0 - 1.5 x10E9/L
Basophils 0.0 0.0 - 0.1 x10E9/L
L Platelets 14 143 - 448 x10E9/L
Platelets appear severely
decreased (< 25 x 10E9/L).
Mild platelet clumping observed
My question is - does he need immediate intervention? Presenting as normal energy/appetite; capillary refill normal; normal gum color; no observed burst vessels in mouth/gums/on belly.
Straight up panic staring at him (and probably confusing him in the process). Any insight very much appreciated!
Paws crossed that Dr. Pam can offer some insight on this. Glad you posted here.
I wish I could help, but I'm just a vet and am not knowledgeable in this department. But what I can say is: keep calm and hop on! He's looking at you to lead the mood, and so the calmer you are the more he will be too!
22 August 2008
Thank you sooooo much Dr. Pam!
Here is a link to the other post for those following along: