Our 6 1/2 year old female lab is crazy.  We call her our ADD child! She has separation anxiety, can't be left alone, can't be crated and gets upset going places.  She also has fear aggression.  She'll do laps in the car around Hunter, her lab brother.  She's also our monkeybutt. 

We have tried a lot of "fixes"... like Rescue Remedy, the Comfort Zone plug in, and holistic meds.

We've tried a Thundershirt as well, but that only helps a little bit.

We have also tried essential oils with her (Young Living brand). Peace and Calming is nice.

And we recently came upon one called Trauma Life.  That one has calmed her down the most.  I apply it to her neck up to the base of her ears so she can smell it.  The first time she smelled it she went from jumping on my husband and wanting to be in his lap to immediately laying down on the floor! 

I hear that combining Trauma Life with Peace and Calming intensifies the effect.

*This is what Young Living has to say about it:

Trauma Life™ is a calming, grounding blend of therapeutic-grade essential oils formulated to help release buried emotional trauma resulting from accidents, neglect, the death of a loved one, assault, or abuse. Left unchecked, emotionally draining episodes may be at the root of fatigue, anger, and restlessness.

I now use it when I have to take her to a vet appt. for Hunter and she's so much easier to deal with.  She also wears a harness which makes it easier to control her body when she's pacing or jumping up on me.

Hope this helps,

Hunter's Mom