TRIPAWDS: Home to 13658 Members and 1543 Blogs.
HOME » NEWS » BLOGS » FORUMS » CHAT » YOUR PRIVACY » RANDOM BLOG

Time to reevaluate treatment plan | Page 2 | Treatment, Recovery and Oncology

JUMP TO FORUMS

Join The Discussion

Learn about life on three legs in the forums below. Browse and search as a guest or register for free to take advantage of member benefits:

  • Instant post approval.
  • Private messages to members.
  • Subscribe to favorite topics.
  • Join the Live Chat and more!

free tripawds account tripawds member log in

K9 Immunity Plus — Hope For Dogs With Cancer

Get help with Dr. Dressler’s Dog Cancer Kit

T-shirts, Cards & Gifts

tripawds t-shirts and gifts

Visit the Tripawds Gift Shop for fun three legged dog/cat t-shirts & more! Browse all designs.

Please consider registering
Guest
Search
Forum Scope




Match



Forum Options



Minimum search word length is 3 characters - maximum search word length is 84 characters
Register Lost password?
sp_Feed sp_PrintTopic sp_TopicIcon-c
Time to reevaluate treatment plan
sp_NewTopic Add Topic
Forum Posts: 120
Member Since:
31 December 2017
sp_UserOfflineSmall Offline
16
12 January 2019 - 12:59 pm
sp_Permalink sp_Print sp_QuotePost

Casey had no problems with carboplatin.  Doxorubicin/Adriamycin was a different story for Jet.  Even administering the Doxorubicin is a much bigger ordeal, and it’s rare with dogs because they receive far fewer doses, but certainly people experience coronary side effects with doxo.

Forum Posts: 303
Member Since:
12 May 2018
sp_UserOfflineSmall Offline
17
12 January 2019 - 3:38 pm
sp_Permalink sp_Print sp_QuotePost

Onco vet wants to do another chemo round with carboplatin or doxorubicin. He perfers doxorubicin because it’s stronger. Simon did very well on carboplatin. No side effects. The choice will be mine. I need to weigh the cost benefits of knowing carboplatin caused no side effects vs the increased strength of doxorubicin with potential for increased side effects. I consider this regimen with “do no harm “ in mind. Any thoughts on the increased strength of doxorubicin and increased side effects vs carboplatin, a bit weaker but more tolerable with no shown side effects noted?

Forum Posts: 120
Member Since:
31 December 2017
sp_UserOfflineSmall Offline
18
12 January 2019 - 7:42 pm
sp_Permalink sp_Print sp_QuotePost

This is an interesting study comparing Carboplatin alone or in combination with Doxorubicin.  Carboplatin alone blew the combo therapy out of the water.  I know that’s not your situation, but it’s worth considering.  https://www.ncb…..MC5012431/

FWIW, I’ve never heard before that Doxorubicin is stronger than Carboplatin.

I also saw that there’s a PEGylated Doxorubicin available now and if that’s like other PEGylated medications, it stays active in the body longer than the standard drug.

Have you considered vaccination?  Are we getting other data regarding effectiveness?  Of course, as it’s still in trial, it may not be covered by your insurance.

Best of luck

Forum Posts: 303
Member Since:
12 May 2018
sp_UserOfflineSmall Offline
19
12 January 2019 - 8:47 pm
sp_Permalink sp_Print sp_QuotePost

Thanks for the reply. Simon was diagnosed from x ray.  No biopsy done.   When i was told that vax required a biopsy, we did a needle stick but no cells showed up. 

Forum Posts: 19
Member Since:
11 January 2019
sp_UserOfflineSmall Offline
20
13 January 2019 - 3:46 pm
sp_Permalink sp_Print sp_QuotePost

Hello, 

Our girl was recently diagnosed with osteosarcoma, and just began carboplatin chemo January 2nd after her amputation two weeks earlier. I did quite a bit of research as we were talking through treatment options, and found some things you might find helpful as well as you think through carboplatin vs. the combination dox and carb treatment. 

I have never heard of metronomics . Will have to look that up and ask our oncologist. 

Here’s a quick abstract from a study that seems to indicate that carboplatin alone is the better option: https://www.ncb…..d/24118677

As for the vaccine, it is VERY promising. The preliminary studies show that it is extending mean survival times from 436 (ish) days with amputation and chemo to 933 days when you add the vaccine to the treatment protocol. We have a vet here that is part of the trial and we are just praying that we can hold off met until the end of chemo so our girl can participate. 

At this point, the only thing I can offer is data, as I have only the early sleepless night experience of a new tripawd guardian. Good luck to you, and I hope you continue to get good news! 

Here and Now


Forum Posts: 11727
Member Since:
25 April 2007
sp_UserOfflineSmall Offline
21
13 January 2019 - 5:38 pm
sp_Permalink sp_Print sp_QuotePost

jenaleigh1 said
I have never heard of metronomics . Will have to look that up and ask our oncologist.

Click any metronomics link for plenty of helpful articles in the Tripawds News blog .

Forum Posts: 120
Member Since:
31 December 2017
sp_UserOfflineSmall Offline
22
14 January 2019 - 9:42 am
sp_Permalink sp_Print sp_QuotePost

I have never heard of metronomics . Will have to look that up and ask our oncologist. 

Be sure to discuss metronomic therapy in conjunction with any vaccine discussions.  Casey was an early participant in the Aratana field trial, but the only prior therapy allowed at that time was Carboplatin.  Metronomic therapy would have disqualified him.  UF is testing a different vaccine, or at least a different protocol, so they may have different rules.

Forum Timezone: America/Denver
Most Users Ever Online: 597
Currently Online:
70
Guest(s)
Currently Browsing this Page:
1 Guest(s)
Member Stats:
Guest Posters: 1029
Members: 9029
Moderators: 2
Admins: 3
Forum Stats:
Groups: 4
Forums: 23
Topics: 15421
Posts: 216431
Administrators: admin, jerry, jim
Moderators: betaman, krun15
Tripawds is brought to you by Tripawds.
HOME » NEWS » BLOGS » FORUMS » CHAT » YOUR PRIVACY » RANDOM BLOG