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Caring for a Three Legged Dog or Cat

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Nova Update - 5 Month Ampuversary + A New Challenge
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Linden, MI
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11 November 2008
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14 April 2009 - 6:03 am
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Nova just had her bloodwork done yesterday, a month after starting Metronomics.  Everything was great!  They did find a little blood in her urinalysis though, I am waiting to hear from the Oncologist today to see what that means. (The lab work was done at my regular vet). She celebrated her 5-month ampuversary on the 11th.  We won't be doing another round of chest x-rays until the summer.

The frustrating thing is that right now Nova is having big time issues with her glaucoma, and may be facing another surgery to have her blind eye removed. She has been pretty much blind in her left eye for over a year now, but now the pressure in the eyeball has gotten tremendously high in the past few weeks, for no apparent reason. Her medication (4 different eyedrops) is just not working anymore. This supposedly means immense pain for the dog, almost like a constant migraine in a human. It is so frustrating to have done everything out there to keep her pain free and happy with the cancer (amputation, chemo, etc.), and then STILL be stuck with the pain of glaucoma. 

I am wondering if there is a chance that some of the Metronomic drugs she's taking might be elevating the pressure in her eye. I am going to take ALL of her medications to the opthamologist today so see if perhaps something is conflicting.

Her other eye is still in good shape, although I am treating it to try to delay the onset of blindness in that eye.  I am hoping that Nova will never become a blind Tripawd, but if she does, I'm sure she'll adapt. I'm still so thrilled that my big ol' couch potato was out climbing mountains last week (see pics under "Hopping Along" - don't know how to post link there) or check out her blog at http://www.trip.....ogspot.com for tons of pictures of a 1/2 blind Tripawd hiking and climbing mountains in NC!

Sue and Nova

Dane Mom Sue at nova.tripawds.com and Mom to Beautiful Great Dane Queen Nova, a Blind Tripawd, who kicked cancer's butt from 11/08-03/13. The Queen is Spirit Nova now, but her legacy lives on here at Tripawds!

Member Since:
25 April 2008
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14 April 2009 - 8:09 am
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Hi Sue,

  My Buster used to have  uveitis before the cancer. He almost lost his eye as well.

Does Nova see a specialist for her eye? I remember Buster actually having injections into the eye as well as prednisone and other meds... he was seeing an ophthalmologist for about 2years prior to the cancer.

I guess you had her urine tested, Did you stop the oral chemo? If so wait to see if that is what is causing her eye pressure to increase.  If her eye is auto immune related anything can cause it to flare up....

I would see another Dr to get their opinion, I understand that she is in pain. Hopefully you'll find the right mixture of drugs to control this....

Hopefully Dr Pam may be able to provide some insight.

Hope you feel better Nova..

Kim & Buster

Kim & Angel Buster

"Until one has loved an animal, a part of one's soul remains unawakened."
–Anatole France

Linden, MI
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11 November 2008
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14 April 2009 - 11:43 am
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Kim - Nova has uveitis and glaucoma and cataracts. Her left eye is entirely blind, but her right is still ok. Yes, I see a specialist (opthamologist) and just got back. It just doesn't make sense to put Nova through a big surgery to remove the eyeball and insert a prosthetic. They gave me a quote and it cost more than the amputation surgery!  So we opted for a different plan. They are going to inject the eye with a drug, I think it's called Propofol, that will kill the affected fluid producing cells within the eye. The procedure will leave the eyeball cloudy with a significant decrease in size.  But it is a fraction of the cost of the surgery.  So she will be having that done on Thursday morning.  She will be sedated, but it is outpatient, so she should be home in a few hours. I am having it done by the opthamologist, which is kind of a long drive. But I don't think my regular vet does this procedure, and I want her in the best care.

This has about an 80% chance on decreasing the pressure. Then I will continue to treat the other eye (which is fine except for a cataract) with much less medication. That will be helpful, as the medications are very expensive (Trusopt, Timolol, Pred Acetate, and Xalatan). The cost of the injection is about 1 1/2 month the cost of eyedrops, plus if it works I will save $100s on emergency clinic visits (it always seems to flare up on weekends and midnights).

I am worried about future trouble in the other eye. I've had a blind dog before, but not a Great Dane, and not a blind Tripawd! If she were blind I would be worried about slips and falls, running into things, etc. Oh well, we will cross that bridge when and if we get there.

I had a great chance to talk about Tripawds with a pawrent I met in the waiting room there. Her dog had injured his leg and they had put him through a half dozen surgeries, and it wasn't helping. He was in constant pain. Amputation was their next option. But her son (about 9-10) was scared to death about amputation.  It was a long wait, so I had a long time to show them Nova, and they were amazed to see such a giant dog do so great. (Their dog was only about 50-60 lbs, and would be a rear amp) I told them all about Tripawds and answered the boy's questions. His key thing was that he wanted his dog to run and play with him again. I told him about all the awesome Tripawds out there who can run, play, and even bragged about Nova's stair and mountain climbing!  It was a great experience and felt wonderful to help someone deal with the fear and confusion when facing amputation.

Sue and Nova

Dane Mom Sue at nova.tripawds.com and Mom to Beautiful Great Dane Queen Nova, a Blind Tripawd, who kicked cancer's butt from 11/08-03/13. The Queen is Spirit Nova now, but her legacy lives on here at Tripawds!


Member Since:
22 August 2008
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14 April 2009 - 2:40 pm
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I have had to remove many eyes due to glaucoma, and I have also done the injections to "kill" the eye.  Either way the pain should go away quickly.

I would be more concerned with the blood in the urine.  If the sample was collected with a needle or catheter then some blood is normal.  Your vet should run a culture to make sure that you don't miss a UTI.  You probably remember that Tazzie had to stop her Cytoxan due to a bad UTI after only 6 weeks on the pills.  She did not even have blood in her urine yet but I caught it early on a culture.

If you decide to keep Nova on the Cytoxan the I have some that I could send you!

Pam and Tazzie

Linden, MI
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11 November 2008
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16 April 2009 - 12:49 pm
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Thanks, Pam.  I spoke with the oncologist yesterday and she said she wanted me to stop the Cytoxan until we could get another urinalysis done. Nova had her eye surgery this morning at the opthamologist, everything went well and she is happy as ever. But I didn't have the 2nd urinalysis done until about 3 this afternoon because my regular vet is 1/3 the price of the specialist!  So they will fax the results over to the onco and take it from there. She hasn't had "typical" symptoms of a UTI so I am afraid that the Cytoxan does not agree with her. But I will let the onco make that call. Is there an alternative to Cytoxan? Is there an advantage to continuing the Piroxicam without the Cytoxan?

Dane Mom Sue at nova.tripawds.com and Mom to Beautiful Great Dane Queen Nova, a Blind Tripawd, who kicked cancer's butt from 11/08-03/13. The Queen is Spirit Nova now, but her legacy lives on here at Tripawds!


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22 August 2008
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16 April 2009 - 7:42 pm
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Yes, I would keep up the Piroxicam since it can help decrease the formation of new blood vessels that tumor cells would feed off of, and will also help keep her comfortable.  Tazzie still takes her Metacam every day and I upped her Artemisinin to 300 mg to make up for the loss of the Cytoxan.  She was taking Artemisinin every night but now she is on it every other day (the preventative dose).  I decided that if she gets lung mets I might give the Cytoxan another try.  She currently is taking 800 mg of cranberry (NatureMade capsules) twice daily to help prevent any more infections.

I am so glad that Nova is doing so well!  So many people (including vets) don't realize that these giant breeds can handle amputation just fine.

Pam and Tazzie

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