My dog, Lulu, had osteosarcoma in her left back leg. Her leg was amputated in June. She did really well after surgery. Her amp site healed with no complications. She was back to being herself in no time at all. She was doing really well until about two weeks ago. She started licking and lifting up her front right paw and her right eye became inflamed. I took her to the vet. The vet checked her neck, shoulder, and leg. It appeared that one of the toes in her foot was sore. The vet x-rayed it and nothing showed up on the x-ray. She had her liver and calcium levels checked which came back fine. The vet also didn't seem concerned about her eye. So, we went home with a rx for rimadyl. The rimadyl seemed to make Lulu lethargic but it didn't seem to help her pain (she would lay on the couch and move her leg continually like it was hurting her). I switched her to previcox which she took pre-amp to control her osteo pain. Lulu's eye got worse so I called the vet and asked for some kind of treatment for her eye. They prescribed some eye drops which didn't seem to help. Then, along with the painful leg and red eye, she began drinking and urinating excessively. I got her a rx for amoxicillin which helped her eye slightly. I took a urine sample to the vet and she has an appt on Monday. She seems to be in a lot of pain and isn't acting like herself. So far, the vet doesn't seem to have any idea about what is wrong. They seem to think its just a sprained toe. I'm worried that its something more serious. Has anyone experienced anything similar? Could it be the cancer taking over? Does anyone have any suggestions? Thanks.