Spending all this time home with Jill during her recovery has given me a lot of down time to do internet research, and while there really isn't a lot out there about Osteosarcoma in cats, almost everything I read says amputation alone (without chemotherapy) is the recommended treatment if there are no signs of spread (which there are not, her lungs are clear).

My vet and vet oncologist have both recommended Jill get chemo once she is healed (in about four weeks).  I usually trust whatever they tell me, as they are both very caring and really seem to have Jill's best interest in mind, but I'm just so confused by this information I'm finding on the internet.  Is there any information you all can share with me? Maybe they suggest the chemo because we found clean margins the first time and a met developed?

To recap Jill's case until this point:

In June Jill developed a large ulcerous mass on the outside of her toe (she never limped or was in any pain I should mention) that wound up being giant cell osteosarcoma. We amputated her toe and they found very clean margins, so at that point the recommendation was to leave her alone and have her lungs checked every six months. Six months later I found a nodule under her skin in the same leg (again no limping or pain and the nodule is not on bone). Her lungs are clear and the X-ray of the bone of her leg looks great.  After amputating her leg, the nodule was biopsied and turns out to also be giant cell osteosarcoma.

Thanks for any advice you can offer....I just want to do what is right for Jill.....