Caring for a Three Legged Dog or Cat

Research behind bisphosphonates for feline bone tumors is sparse. But while searching for palliative care pain management of feline bone cancers, I came across this one study about bisphosphonates for cats with limb cancers.

If you find others please add to this discussion.

Pamidronate Disodium for Palliative Therapy of Feline Bone-Invasive Tumors

This study sought to quantify in vitro antiproliferative effects of pamidronate in feline cancer cells and assess feasibility of use of pamidronate in cats by assessing short-term toxicity and dosing schedule in cats with bone-invasive cancer. . . . Pamidronate therapy appears feasible for administration in cancer bearing cats with aggressive bone lesions in the dose range of 1-2 mg/kg every 21–28 days for multiple treatments. No acute or short-term toxicity was directly attributable to pamidronate.