jerry said
Drats, I'm just so sorry the Palladia is giving him such a hard time. Poor guy, I know you must be so worried. Tomorrow you should have some answers for your just-say-no-to-drugs kiddo. And never apologize for any thing like sharing a grody side effect, it's reality and it's good to share so that anyone else going through it with their pup doesn't fee alone. 

Regarding the Palladia, see if your onco vet thinks that Odansetron could work. It's pretty powerful for settling a nauseated belly.

Keep us posted, know that your happy crazy boy is still there, and remember we are sending you guys the full force of Tripawds Pawsitivity! 

  

I asked about Odansetron and she (onco) said yes, it could help, and she will order it for us tomorrow in case he is still refusing food and nauseous. Thank you for mentioning that!!

We made it through a very rough patch. Poor Zeus was so nauseous from 5am until about after lunch time. He was licking everything in sight, burping, trying to throw up but since his stomach was empty there was nothing to bring up. He would not take anything we offered, and the little that he did he would spit it right out - but he did drink water and kept it in which was a good sign. I guess Palladia really wrecked his system. He finally settled around 2pm. I gave him a bit of time then slowly introduced boiled chicken and then a bit more and he ended up eating two chicken breasts and some pumpkin and fell asleep so peacefully. I felt so happy, and relieved, for him to finally get some rest. And then I passed out right next to him!

If we had any indication that Palladia would cause him this much discomfort we would have never opted for it. I though the worst thing would be diarrhea. But hindsight is always 20/20.

I was in touch with his oncologist throughout the day, she wants to wait at least a few more days before we make any further decisions. She said that Chlorambucil 4mg taken daily is unlikely to cause any side effects, but as expected, I am now terrified of another reaction. We are taking it day by day for now and I have no idea how we are going to proceed. First priority is to have him eating again and settle his entire body.

From everything I read about possible side-effect of Palladia Zeus is truly an exception to have such a strong reaction from breathing issues to severe nausea. I do still think that Palladia does wonders in reducing the size of the lung nodules and is even promising in completely shrinking them to nothingness. Who knows what else played a part in Zeus getting so sick from it. We will never know for sure but we are moving on.

After many, many conversations with Zeus's oncologist we have decided to continue with Chlorambucil. She assures us, as much as that is possible, that the medication is very well tolerated. I do want him in my life as long as possible however not at all cost. At the first sign that he is having a reaction I am going to stop it and let him just be happy.

So... I have some technical questions regarding the proper handling of medication and related human exposure without limiting the necessary affection and protecting our cat as well. There are many things to consider and even though we have the instructions from the clinic they seem to be vague and general. Are there any big 'no-no' to worry about? I've read that the bottle should not be sitting next to human food - ours has been in the fridge since January 4th in close proximity to our food.

Also, we often play with puzzle toys and Zeus starts to drool at a first glance of a treat and it always ends up as a messy game but so much fun - do I need to worry about it now?

I figured I would come here to get the best suggestions on how to handle things - I know a lot of it is common sense but you are dealing with a human that will use peppermint oil for headaches and advil only as a desperate measure and a very last resort.

[Image Can Not Be Found][Image Can Not Be Found][Image Can Not Be Found]