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Max & The Metronomic Protocol
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Orange County, CA
Member Since:
28 November 2008
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22 April 2009 - 7:07 pm
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Hi everyone.  There have been a lot of sad postings on Tripawds.com lately (Wrigley, Buster, Cooper, Blue, Matey Girl, Rocco, Dasha, Cody; too many!!! Crying).  I have a bit of good news, and maybe eventually some hopeful news a bit down the line.  Max finished his traditional chemotherapy treatments (6 rounds of carboplatin) on 3/21/09.  He had lung x-rays on 3/21/09 and 4/18/09, and they both came up clear.  Since his chemo was finished, we consulted with Max's oncologist as to any other options available to us.  We had two:  chemo is done, so hang out and see what happens; or start the Metronomic Protocol (low-dose chemo in a pill that can be given at home).  I already knew about the Metronomic Protocol from reading about Jerry's experience with it.  I had read in other places that basically it was a kind of “last resort” treatment, as lung mets had already developed in those that went on it. 

After much thought, we decided to go ahead and do it. Since Max has no lung mets at this time, this is purely a preventative treatment.  We don't know if it will help extend his life, or keep mets at bay any longer than if we hadn't tried it.  (Has anyone else here tried the Protocol without lungs mets having been discovered???)  But we figure it's worth a chance.  Max is also taking K-9 Immunity and Transfer Factor; he will continue with those along with the Protocol.  So, we'll see what happens with this.  We don't know what it will bring, or how long we will keep Max on it (we've decided that if any of the medicines adversely affect him, we will discontinue the treatment), but we hope it will do something good.  Here are Max's medicines:

Actos (generic for Pioglitazone): 30 mg tablet, one tablet every 24 hours

Piroxicam (generic for Feldene): 10mg capsule, one capsule every 24 hours; this is an NSAID

Cytoxan:  don't have this dosage yet b/c we have to get it from a different pharmacy

So, I'll keep this forum updated on his treatment and future blood tests/x-rays.  If I have my way Wink, I will have nothing but good news to post here for others that are looking for additional treatment options.

Thanks,

 Di & Max

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Northern CA
Member Since:
23 December 2008
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22 April 2009 - 8:41 pm
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Good news is a win for our team- we'll take it.  We look forward to many more good news posts.

We'll be cheering you on!

Seanne and Angel Wrigley

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13 January 2009
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22 April 2009 - 9:57 pm
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Indeed this has been a very hard few weeks for our Tripawd community.   I'm very happy to hear about Max's progress.  Congrats Max on finishing chemo!  I'm very eager to learn about how you are doing on the Metronomic Protocol, keep us updated.  Shadow goes in for his last chemo treatment next week....his chest x-rays from 2 weeks ago were clear. (we are 3 months post-amp)  The Metronomic Protocol might be something we will put Shadow on too once he finishes traditional chemo. 

Hopefully we can get our So Cal Tripawds beach day soon.  It's getting warmer! 

Hugs!!

Tina and Spirit Shadow

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Member Since:
22 August 2008
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22 April 2009 - 10:43 pm
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I put Tazzie on the Metronomic Protocol; we started 3 weeks after her last dose of carboplatin.  Her chest rads were also clear and bloodwork was normal.  We just did the Cytoxan (25 mg once daily) and NSAID (meloxicam 7.5 mg daily).  Tazzie tolerated the protocol well for 6 weeks, but then she developed a bladder infection secondary to the Cytoxan so we stopped that drug.  I may try it again if she develops lung mets but for now she just takes the meloxicam and artemisinin as well as fish oil and several other antioxidants.

Pam and Tazzie

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4 December 2008
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23 April 2009 - 7:39 am
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Hi Di and Max:

Tika is doing metronomic protocol also and so far she is clear of lung mets.

She is on piroxicam and cytoxan right now, we are not doing the third one at this time. I think I posted the dosages elsewhere in this site.  They both have to be compounded at a 'human' pharmacy.

She takes to it pretty well, she will get an upset stomach if she gets her piroxicam to long after she eats her meal, but the Cytoxan seems to be doing fine.

Good luck with the protocol, I'm crossing my fingers for all of us!

--Kim

Kim and Spirit Tika http://www.tika.....ogspot.com

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On The Road


Member Since:
24 September 2009
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23 April 2009 - 11:24 am
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Yay! Wonderful news for Max! Big Grin Thanks for this update and for sharing the details of your chosen metronomic protocol treatment.

For those who haven't seen it, be sure to check out our video of Maximutt playing on the beach where he clearly says what cancer!?!?

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

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My heart lives at Rainbow Bridge
Member Since:
28 November 2008
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23 April 2009 - 6:00 pm
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Great news, Max.  This is a much needed boost to team tripawd.  We have had lots of bad news lately, and hopefully this will be the beginning of a string of positive happenings with our fur kids.

Shanna & Spirit Trouble ~ Trouble gained her wings 3/16/2011, a 27 1/2 month cancer survivor, tail wagging. RIP sweetheart, you are my heart and soul.  Run free at Rainbow Bridge.
The November Five - Spirits Max, Cherry, Tika, Trouble & Nova. 11/2008 - 3/2013 An era ends as Queen Nova crossed the Bridge.

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