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Jackson urinary cystitis, after 5 months of metronomics
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New Haven, CT
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28 August 2013 - 6:39 am
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Hi all!  I'm back from my trip and I'm happy to report that Jackson's pee-problem is just about solved.  I'd say we're at 95% improvement!  YEY!  Today marks 6 WEEKS of being off cytoxan.  Holy cow, I never thought it would or could take this long.  Awful.  He had many accidents in the house, but they tapered off and ended the third week in.  He stayed on Cranimals and TractEast until we ran out (4-5 weeks) and I don't think we need them anymore.  I suspect by next week, we'll go back to his normal amounts of MSM and Rimadyl, too.  We'll also head back to his onco to have a checkup and she'll probably bump up his luekeran dose (b/c she kept it low while we were away).

Would I try cytoxan again?  I would, b/c it's cheaper, had more stats, and some dogs really tolerate it well!  I would advise, though, to any one who's going with cytoxan, to know exactly what the symptoms of a UTI and cystitis are, so at the first sign, you stop.  I had my head in the sand and think Jackson was symptomatic for about a week before we stopped it.  I know we gave Jackson every chance and opportunity to not have problems (MSM, loads of fresh water, frequent walks), but this med does this!

If you're considering cytoxan or luekeran, ask yourself and your pup (or kitty!) if a 6 week pee-problem with accidents and discomfort is something you and your pal can handle.  It's not a given it'll happen, but luekeran supposedly doesn't have this risk...

~ Katy & Jackson

ACL tear in right hind leg 12/5/12 and scheduled ACL repair surgery 12/21/12. Pre-op xrays revealed osteosarcoma. Amputation 12/28/12.  Chemo (carboplatin) started Jan 10, 2013 and ended on April 5, for a total of 5 doses. He handled carbo like a champ!  No side effects.  We started metronomic therapy at his third chemo and have been also doing some holistic treatments.  He's a lively, playful 10 year old huskie-boarder collie and a very proud member of the Winter Warriors!  Our love. Our funny little guy!

The Rainbow Bridge



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28 August 2013 - 9:05 am
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Welcome home from the trip of a lifetime! I loved the cheetah video. How cool!

But even better is the fact that Jackson has almost totally recovered. YAY! What a relief for everyone. We are very, very hoppy to read this.

I'm not sure if you saw this post it may have run when you were away:

Cyclophosphamide vs. Chlorambucil in Metronomic Chemotherapy

We will be running another post on this topic soon, an interview with oncologist Dr. Intile, who prefers using Leukeran (chlorambucil) for metronomics . Stay tuned!

It's better to hop on three legs than to limp on four.™
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New Haven, CT
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28 August 2013 - 9:38 am
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And see my post, too, about this important issue: http://tripawds.....-leukeran/

 

~ Katy & Jackson

ACL tear in right hind leg 12/5/12 and scheduled ACL repair surgery 12/21/12. Pre-op xrays revealed osteosarcoma. Amputation 12/28/12.  Chemo (carboplatin) started Jan 10, 2013 and ended on April 5, for a total of 5 doses. He handled carbo like a champ!  No side effects.  We started metronomic therapy at his third chemo and have been also doing some holistic treatments.  He's a lively, playful 10 year old huskie-boarder collie and a very proud member of the Winter Warriors!  Our love. Our funny little guy!

Atlanta, GA
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28 August 2013 - 10:17 am
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So glad to hear Jackson is getting better.  And wanted to tell you we've missed you, welcome back.

Adelaide is a young tripawd Husky, from an injury.  Her amp was on 10/1/12.  She has 4 sisters, Aissa (a senior border collie/chow), Maggie May (a puppy Great Pyrenees), Mathilde and Morrigan and 1 baby brother, Bagheera.  We are all watched over by our angel Brendol, who was dx with OSA 1/30/13, amp on 2/6/13, and left us on 8/20/13.

PitaPata - Personal picturePitaPata Dog tickers

 You can read their stories at http://adelaide.tripawds.com and http://brendol.tripawds.com
Virginia




Forum Posts: 21441
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28 August 2013 - 11:04 am
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Just more validation of why this is the most informative site ever! Thank you!

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

New Jersey
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28 August 2013 - 7:40 pm
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Great news about Jackson feeling and getting better. Glad toy had a good vacation, I'm sure soooooo needed!
Esther and Snoopbig-grin

Southwestern Ontario, Canada
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22 November 2012
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30 August 2013 - 12:54 pm
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whoo hooo!!  It makes us smile on this side of the computer when we read great stores!

And we can always use another smile!!

Christine..... with Franklin in her heart ♥

Franklin, he was the Happiest Dog on Three Legs! Diagnosed 09/26/2012 with Osteosarcoma, amputated 12/4/2012.  Had a wonderful 5 1/2 months painfree until he ran for the Bridge on 5/15/2013.  Always in my heart, and always a guardian angel of my pack...   You can follow his Tripawd Adventures, before and after, in my blog, Frank'n'Farter!

New Haven, CT
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4 September 2013 - 1:58 pm
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Hello! For those following Jackson's pee problems and switch to leukeran....

I just heard from his onco and his blood and urine is all back to normal!  Not even any microscopic blood in his pee.  Whoop whoop!!!  Let's see, to this day, it's been 7 weeks OFF cytoxan.  He's been on leukeran for about 5 weeks, too.  We were wondering if 1.5mg/day of it after 5 weeks would do anything to his WBC.  His numbers are normal and all OK.  However, I did ask for specifics and there was actually a downward trend, but still within the normal range.  So, we'll watch that.  He'll get new urine and blood tests in a month.

A good day!  It's nice that his clinical signs match the lab tests and I'm hopeful that the increase to 3mg/day of leukeran won't impact him.  As usual around here, I'll keep a watchful eye!

~ Katy & Jackson

ACL tear in right hind leg 12/5/12 and scheduled ACL repair surgery 12/21/12. Pre-op xrays revealed osteosarcoma. Amputation 12/28/12.  Chemo (carboplatin) started Jan 10, 2013 and ended on April 5, for a total of 5 doses. He handled carbo like a champ!  No side effects.  We started metronomic therapy at his third chemo and have been also doing some holistic treatments.  He's a lively, playful 10 year old huskie-boarder collie and a very proud member of the Winter Warriors!  Our love. Our funny little guy!

Virginia




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4 September 2013 - 2:24 pm
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OH! This is great news! 'Been waiting for a "pee" post! YAAAAAAAAAY Jackson!

Happy Hannah is just finishing her antibiodic today It wasn't til your post last week that I definitely decided NO to the Cytoxan and go with Luekeran instead. Just not willing to risk these kinds of flare-ups I haven't spoken to the onco. any further on this after she originally kinda poo-pooed the idea originally and said let's get the tap, clear it up, etc., etc. first. These "people" don't seem to have any sense lf urgency about anything! Of course she's out til Monday

I'm so relieved for you Katy! I kkw this has been Worrisome and frustrating" to say the least!!

We celebrate pee updates around here! Passing out the Crananimals in Jackson's honor......you know what I mean.....the cranberry vitamins:-) :-)

HUGE GIGANTIC HUGS TO YOU VOTH!

Sally and Happy Hannah

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!



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4 September 2013 - 2:56 pm
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Awesome news Katy. Hugs to both of you.  Keep up the good work J

 

 

Hugs

Michelle & Angel Sassy

sassymichelle-sm.jpg

Sassy is a proud member of the Winter Warriors. Live long, & strong Winter Warriors.
sassysugarbear.tripawds.com
07/26/2006 - Sassy earned her wings 08/20/2013

05/04/2006 -  Bosch, Sassy's pal, earned his wings 03/29/19  fought cancer for 4 months.

"You aren't doing it TO her, you are doing it FOR her. Give her a chance at life."

New Jersey
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4 September 2013 - 2:59 pm
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Katy,
Great news about Jackson. Keep going strong.

Esther and Snoopclap

The Rainbow Bridge



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4 September 2013 - 9:39 pm
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That is PAWSOME news Katy! Jackson is just ammmmaaaaaaaazing!!!!

WOOHOO!

It's better to hop on three legs than to limp on four.™
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