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Auranofin Treatment Thoughts?
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Member Since:
23 April 2020
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14 May 2020 - 1:45 pm
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Hey Everyone - Was wondering if anyone here in the tripawds community had experience with Auranofin?  Being told it could be a good addition to standard chemo protocol.  It definitely has some sticker shock though with a high $$$.  If anyone has any thoughts or recommendations on bringing the price down I'd be all ears.  Thanks!

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14 May 2020 - 2:44 pm
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greyhounddad22 said
...anyone here in the tripawds community had experience with Auranofin? 

Have you searched these forums yet?

Search results for 'Auranofin' (4)

Use the Advanced Search features for best results. Select "Include Blog Posts" to also search the Tripawds News blog .

You can also search all blogs here .

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

New York, NY
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16 May 2020 - 12:13 pm
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Hi Paul!  After you first mentioned Auranofin (I think Ridaura is the brand name), I shared the abstract of the pilot study with Griffin's oncologist, who said that the dosage would be 9mg every 3rd day.  She said that she would want Griffin to finish chemo before starting this drug due to the potential side effects (bone marrow, GI, liver and kidney toxicity), although those were reported in higher dosages of 9mg each day.  She said if I wanted to move forward now, she would recommend weekly blood work to monitor for toxicity.  I then found this Treatment of Metastic Osteosarcoma, which describes the study and lists the dosage as 3mg every 3rd day.  I haven't heard back from the oncologist yet after sending the summary, because the dosage difference would be a huge factor in terms of reducing chances of toxicity and also of cost.  I looked into purchasing the drug online from Canada, where is seems that 60 pills in 3mg dosage is about $425.  Arktik's mom, Patricia, posted about Auranofin today and I asked her to post on this thread.  She said the drug wasn't too expensive (she is in Canada), so hopefully she'll have more information to share.  Thanks so much for bringing this topic to the forum.  The study seems really promising in terms of preventing lung mets, which would be huge for pups with osteosarcoma!  ~ Stacy

Griffin lived an amazing life for 11 years! Diagnosed with osteosarcoma on March 17, 2020, Griffin's right forelimb was amputated on April 2, 2020. Ten days later he was running and playing fetch! Lung metastasis discovered in July 2020 did not slow down Griffin and he lived joyfully for the next 7 months, passing peacefully at home on February 11, 2021. https://griffin.tripawds.com

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16 May 2020 - 12:46 pm
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I agree, this is suuuuper helpful information to have here. Thanks guys!

Tripawds Founders Jim and Rene
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19 May 2020 - 8:12 pm
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Hi All,

Last week in our second appointment for chemo, the oncologist mentioned Auranofin as a new treatment that became available for us. I was very curious as it seemed interesting (I only found one recent article on it). Also, it was surprisingly not too expensive. I have to admit we are really at the top of our budget with the ampu and the chemo. But here it was only 250$ (at this point we thought this was fairly cheap all things considered). I am not sure this is for how many pills, I have not received it yet. 

The oncologist suggest we start it as soon as possible, even if we have not finish chemo yet. I believe it will be on smaller dosage (maybe similar to what Stacy was saying with 3mg every 3 days) because they mentioned it would be every 3 days. The reason I don't have it with me yet is that we took a couple of days before deciding about this, so the clinic is shipping it to us. I should receive it tomorrow I believe. I will know the details of the treatment. 

I also read about possible toxicity but it seemed mainly at larger dosage. And our oncologist mentioned the dosage is pretty low, so not many side effects. 

I will keep you posted!

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20 May 2020 - 11:08 am
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Thanks for bringing your experience to this discussion! Paws crossed for a good experience for you, let us know how it goes.

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

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20 May 2020 - 2:01 pm
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On The Road


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20 May 2020 - 7:38 pm
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Pawesome! Thank you so much!

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

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24 May 2020 - 5:34 pm
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Sorry for the late update! I have been taking advantage of the amazing weather we have been having the past week 🙂 Arktik had a blast playing outside (even though he thinks it is a bit hot with his winter coat still on ..he likes to shed only in June icon_rolleyes)

So about the prescription of Auranofin I got, the treatment is 3 pills (3mg each) every 3 days. So it is 9mg once every 3 days. Which is consistent with what Stacy said in an earlier post as well in terms of treatment. Not sure why it is like this instead of 1 pill/day. I will ask in my next appointment. I just got started, so far so good. 

New York, NY
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24 May 2020 - 6:28 pm
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Hi Patricia!  Glad that you and Arktik are enjoying the outdoors and nice weather!  My oncologist said that the original study I sent her indicated the 9mg every 3 days as dosage, but then I linked a summary paper in this thread that said 3mg every 3 days.  It's nice to have confirmation from your oncologist.  Would you mind sharing how much a one month (30 pills) supply costs in Canada?  Is it about $200 USD?  Thanks!

Griffin lived an amazing life for 11 years! Diagnosed with osteosarcoma on March 17, 2020, Griffin's right forelimb was amputated on April 2, 2020. Ten days later he was running and playing fetch! Lung metastasis discovered in July 2020 did not slow down Griffin and he lived joyfully for the next 7 months, passing peacefully at home on February 11, 2021. https://griffin.tripawds.com

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24 May 2020 - 6:36 pm
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Auranofin sounds like something worth looking into. Is it typically taken while a dog is undergoing IV Chemo treatment or after?

I will be sure to ask Copper's Oncologist about it. It's interesting that in the pilot study Stacy posted it states "AF improves OS in male dogs" - Copper is female, so i'll be sure to ask about why that might be too.

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25 May 2020 - 8:53 am
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From what I read on the topic I believe it is definitely worth trying it. It really just became available here has when I first met with the oncologist at the end of March this was not available. He just mentioned they had it on the second round of chemo 2 weeks ago.

In terms of price, I paid 250$ CAD for 21 pills so not a full Month but 21 days of treatment. Which I believe is what my oncologist suggested. But I will discuss it more on my next appointment in 10 days. 

New York, NY
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25 May 2020 - 10:40 am
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Thanks for the update, Patricia!  I don't know why I thought this would be an ongoing prescription, not one for a set period of time like 3 weeks.  Oakley's dad, Paul, was the first to raise the topic of Auranofin on here, so maybe he can weigh in with what his oncologist recommended.

Griffin lived an amazing life for 11 years! Diagnosed with osteosarcoma on March 17, 2020, Griffin's right forelimb was amputated on April 2, 2020. Ten days later he was running and playing fetch! Lung metastasis discovered in July 2020 did not slow down Griffin and he lived joyfully for the next 7 months, passing peacefully at home on February 11, 2021. https://griffin.tripawds.com

On The Road


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25 May 2020 - 11:54 am
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This is all such good information to know about. I'm learning a lot, thanks everyone for sharing.

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

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1 June 2020 - 12:54 pm
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I asked Copper's Oncologist about Auranofin and she is currently looking into it for me. Looks like in my area it cost ~1,300$ for 60 pills according to GoodRx! My Oncologist is reaching out about cost as well. I will update y'all as I know more. 

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