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Tika's IL-2 update
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Member Since:
4 December 2008
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1 September 2009 - 11:13 am
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Tripawd editor's note: To follow in chronological order, please see Tika's previous update, "Tika's IL-2 Update."

Hi everybody:

 

Well….the IL2 treatment didn't succeed as we hoped. However, the oncologist was encouraged by the fact that even though her mets have grown, they haven't grown at the rate she would expect.

 

So, she is going to confer with another oncologist from the University of Missouri (Dr. Kim Selting) about the next step of the plan.  Which is inhaled chemotherapy with carboplatin and gemeticibine, I believe were the two drugs.  We had be stalling on this because it will require our girl to be sedated for a small period while they deliver the dose into her lungs by scope and we really, really, really were hoping that the IL-2 would work.

 

They are also going to figure out whether or not to do the remaining 15 days of IL2, keep on the metronomic protocol, etc.

 

We are getting a set of the Xrays tonight on CD, I'll get them posted so people can see what those stinky old lung mets look like.

 

If this next treatment doesn't work, I don't know what we'll do.  It will probably be time to let nature and Tika decide the path from there on out.  

 

Thank you all for your support and well wishes, it means so much to all of us.

 

All the best,

 

Kim and Tika

Kim and Spirit Tika http://www.tika.....ogspot.com



Member Since:
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1 September 2009 - 11:35 am
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Kim I am sorry to hear that the Interleukins did not work.  Has your oncologist considered Palladia?  That is kind of the plan for
Tazzie if she gets lung mets. I know it is not labeled for OSA but it has helped some dogs with cancers other than mast cell tumor.

Pam and Tazzie

On The Road


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24 September 2009
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1 September 2009 - 2:24 pm
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Kim, we were thinking of you guys all day. Damn! We feel so badly that those tumors didn't disappear with the treatment. We know how heartbroken you must feel. It's so so hard, but think pawsitive and remember, there are options that can help keep those nasty things at bay.

Sending lots of love and hugs your way....

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

Winnipeg
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1 September 2009 - 2:48 pm
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Kim

I am very sorry the IL did not work as well as you had hoped. That news has to hurt and we all had high hopes for this. It sounds as though the growth is slow and Tika is still doing well, isn't she? You are fortunate to have an oncologist to consider and oversee so many treatment options.

Susan & Tazzie 2

My heart lives at Rainbow Bridge
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1 September 2009 - 3:57 pm
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Kim, I'm sorry the news wasn't what you had hoped for.  I so wanted Tika's treatment to be a new beginning, now just for her, but for those to follow.  Stay positive, keep living a day at a time and we'll be here with you.

Shanna & Spirit Trouble ~ Trouble gained her wings 3/16/2011, a 27 1/2 month cancer survivor, tail wagging. RIP sweetheart, you are my heart and soul.  Run free at Rainbow Bridge.
The November Five - Spirits Max, Cherry, Tika, Trouble & Nova. 11/2008 - 3/2013 An era ends as Queen Nova crossed the Bridge.

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1 September 2009 - 7:30 pm
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Kim and Tika,

I'm so sorry to hear that Tika's treatment results were not what we all hoped they would be.  My prayer will be that the vet will be able to do the new treatment and that it will be successful.   Again, I am so sorry.  You have been blessed by and have blessed Tika.

Debra & Emily

Debra & Emily, a five year old doberman mix, who was diagnosed with an osteosaecoma. She had a right rear leg amputation on May 19, 2009. On November 10, 2009 she earned her wings and regained her fourth leg.

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2 September 2009 - 8:40 am
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Hi all:

Thanks for all of your thoughts.  We are waiting to hear from the folks at Mizzou (University of Missouri to those outside the Big 12 area) to see if she can come in tomorrow for her first treatment.

Pam--It was the research and inquiries on Palladia that had started the whole IL-2 thing going.  Our oncologist was worried about side effects with the Palladia so started looking into other options for us.

I guess I left out the most important part because I've been looking at what's going on inside Tika so much.  Tika is doing great.  She's starting to show some impatience with her IL2 treatment (which we have continued for now).  Dad had missed the weekly McDonald's french fry routine last week while I was gone so when I brought French fries in I had Miss Thing doing a one-legged Malamute Riverdance. So, she's doing A.O.K.

So, we will hope for the best.  We got a road trip this weekend, still trying to figure out where to voyage, probably go down to the Ozarks so the girls can romp in the trees and streams.

Cheers all!

Kim

Kim and Spirit Tika http://www.tika.....ogspot.com

Winnipeg
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2 September 2009 - 8:50 am
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Kim

Who is your oncologist? I mean, not by name, but is she based in your home town or did you find someone to consult from long distance? It is amazing she has spent the time to track down new treatments.

Now that I am in a city with no oncologist within a 12 hr drive (the closest vet school), we will probably need to find someone to consult from afar.

Looking forward to hearing what you decide to do and glad to hear that Tika is still dancing!

Tampa, FL
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2 September 2009 - 11:54 am
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Dear Kim,

Bradley and I just started following Tika's story yesterday.  I am so sorry to hear the IL-2 wasn't as effective as you had hoped.  We are thinking about you guys lots and hoping you have fun on your road trip this weekend.  Hopefully, the new treatments are successful in shrinking those nasty mets! 

We'll keep checking on Tika's status!  Be well.

Our best,

Erin & Bradley

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2 September 2009 - 12:56 pm
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Tazzie:

We live outside the Kansas City metro area so we go to Overland Park, KS VSEC for oncology treatment.  We have a fantastic vet as our primary care so we are very lucky.

We had VSEC do the original surgery and treat everything that has to do with cancer.  It's been a 40 minute drive each way once a month, but not so bad.

University of Missouri is in Columbia and is a little under three hours for us, still not bad....

You are in Winnipeg right? How far away is University of Minnesota from you?  They have also been instrumental in assisting us with treatment options.  Here's a link to the cancer care center  http://www.cvm....../home.html

--Kim

PS (to everybody also): Tika will have her first treatment with inhaled chemo on Friday.  I need to thank my hubby's tenacity for that.  AND!!!! We will probably stop IL-2 and go back to exploring the Palladia option, although that will probably mean stopping the metronomic. 

Kim and Spirit Tika http://www.tika.....ogspot.com

Winnipeg
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2 September 2009 - 1:16 pm
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Tika - a big thanks from Tazzie. Yes, I think Minnesota is a mere 10 or 12 hr drive from us, so probably as near as the closest Canadian vet hospital (USaskatchewan), plus I noticed the role that UMinn has played with your girl. Thank you for the link.

We wish you the best for Tika's next journey and are definitely impressed with your husband's tenacity! I see you still have hard decisions to make: palladia vs. metronomics vs. . .

At least Tika is doing her job by enjoying life and smelling the stinky fish (somehow "smelling the flowers" does not sound right for a dog, in fact, if it were Tazzie, it would be more like rolling in the stinky fish).

Susan

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2 September 2009 - 4:52 pm
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The tiara is tooooo cute!

Debra & Emily, a five year old doberman mix, who was diagnosed with an osteosaecoma. She had a right rear leg amputation on May 19, 2009. On November 10, 2009 she earned her wings and regained her fourth leg.

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8 September 2009 - 11:17 am
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Hi everybody:

Well, it's been a hell of weekend.  We were wondering if this post would be under 'Coping with Loss' or not.  We arrived in Columbia, MO Thursday night and everything seemed to be doing okay. Tika didn't want to eat, but she's like that when we travel, she just wants to go out and explore.

Friday morning Tim takes Tika in for the inhaled treatment, that's when the bad news started hitting us.  The lung tumors, some of them are too big and the inhaled chemo will not affect them.  However, it will work on the smaller tumors.  Her cancer is very aggressive.  Then, pre-procedure tests come in, she's got ulcers and a kidney and/or bladder infection. They are going to start with antibiotics first (cipro), and then follow up with an ultrasound of the bladder if needed.  We started giving Prilosec along with her sulfracate to calm and protect her stomach.

They proceeded with the inhalant chemo (gemcitabine and cisplatin) for the smaller tumors and once her stomach settles a bit we will try Palladia for the bigger tumors.  

However, this will probably only buy her 4 months more at the most if it succeeds.  If this doesn't succeed she does not have much longer with us possibly two months at the most.  So, I'm calling in miracles here.

So moving on, we get Tika back, her treatment got delayed because the anesthesiologist got called away because a tiger came in.  Yes. A TIGER!  That brought some amusement to a otherwise bummer day.  We got her back around 4pm and let her rest some.

Saturday--Tika doesn't want to eat and looks wiped out. She's drinking and urinating.  It's raining out so we hang out in the camper for awhile, Tika starts coughing.  I look down as she coughs up some blood on her little baby polar bear.  I lose it.  It wasn't much, but seeing those two red splatters on her white toy just tore me in two.  Tim emails the oncologist Dr. Selting and we keep watch on Tika.

For the rest of the weekend Tika seems to rebound and just wanted to be out, she wanted to wander around and explore (we were right by a dog park and eco-park on the Missouri River in St. Charles)  and we let her lead the way and give her time to rest etc.

Sunday night she vomits, however, I can't be sure that's cancer related because our other dog also vomited, actually bazooka puked would be the term.  We have no idea what triggered them off, it might have been too many treats (NOT MY FAULT) or them splashing around in the rain puddles.

Monday, all hell breaks loose, Tika won't get up, can't get up. I'm crying. We finally get her moving around and she goes potty and drinks some water, still doesn't want food, dad gets her to snack on a little lunch meat.  We head home.  We get home and we have a hard time getting baby girl to move.  We finally do and get her to eat some canned food (Science Diet Cancer Diet) and then let her rest.  

I was a mess last night, she looked so pathetic and miserable, I thought WHAT HAVE WE DONE?  We were both feeling guilty, did we put her through too much, should we try to do inhaled chemo again, did we let her overdo it.  She showed no signs of stress or wanting to stop all weekend, she was enjoying herself, visiting with people. Spreading the word that Tripawds with cancer can still live a good life.  But this abrupt stop of all activity has torn my heart out, we thought we might lose her last night, so I was constantly checking on her (Tika was more like, JUST LEAVE ME ALONE)

I finally got some sleep and we woke up and Tika IS much better, still not too keen of getting up and moving, but seems to be doing okay when she does, her appetite is a little stronger.  I worry that we've screwed up her remaining back leg, but hopefully she's just sore because her idiot parents let her overdo it.  

We will be stopping the metronomic protocol to pursue Palladia.  IL-2 treatment is done, so maybe we knocked out a statistic so it can work on somebody else?

Here's what lung mets look like if you are curious.  I do not wish these images on anybody...

May XraysImage Enlarger

Side Xray taken May

 

Sept XraysImage Enlarger

Side Xray taken in September 
  (each 'snowflake' is a met)

So it's been a topsy turvy weekend, anguish mingled with joy.  I'm with my girl now hoping she gets her strength back

And trying desperatly to not project my emotions on her.  And boy that's hard because she's very much in tune with me.

Anyway, thanks for your patience as I ramble on.  Tika has a followup on September 17th to look at kidneys/bladder/lungs as necessary.  However, if she takes another turn for the worse, we might just say enough is enough, let's just work on making her comfortable now.

--Kim and Tika

Kim and Spirit Tika http://www.tika.....ogspot.com

Oakland, CA
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8 September 2009 - 12:32 pm
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Dear Tika and Kim,

We are so sorry that you are going through this ruff time. Please know that our thoughts are with you and that you will have the strength to get through this. Try to keep it in the here and now--just be together and enjoy each moment to the fullest. Tika, you are so beautiful in your tiara! And Kim, your sense of humor is wicked and will help to see you through this. All the best to you and the rest of your family,

thinking of you here in Oaktown,

Codie Rae and Martha

Woohoo! Tripawds Rule!

Regulator of the Oaktown Pack, Sheriff of the Oaktown Pawsse, Founding member and President of the Tripawd Girldogs With 2 Names ROCK Club, and ... Tripawd Girldog Extraordinaire!

Visit Codie Rae's Blog!

On The Road


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8 September 2009 - 1:21 pm
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What have you done? Oh, just everything possible to maximize Tika's quality of life. And don't forget it. Bless you for taking such good care of your girls and helping her enjoy every day to the fullest. Keep up the good work. There will be plenty of time for tears later. Hopefully much later!

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

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