Hi all! I’m so lucky to have found this group! I am mom to two human kiddos and a 4 year old 90 pound Mastiff/Pitt mix named Baylee.

A couple of weeks ago we noticed lameness and limping in her right hind leg. Initially I wrote it off, called our vet no openings till the following Saturday. No biggie. The next day her joint is swollen and it’s worse. Called our vet again. Again told they can’t get her in. So I take it upon myself to call another vet in town. Needless to say we got the dreaded diagnosis after a bone biopsy 9/2 last Tuesday 9/14.

Talked it over with our vet. Chest X-ray looked good during biopsy, he explained the aggressive nature etc. we decided to opt for amputation and chemo to give her the best chance at a pain free life where we can all enjoy each other as much as possible till either she is healthy again or she gets worse and she is ready to go. Scheduled amputation for today 9/22.

We had a planned and paid for family vacation last week where we opted to board her at the vets office while we were gone. Better safe than sorry. She has been routinely taking Vetprofen and gabapentin for pain since 9/2. Picked her up Monday, noticed extremely dark urine. Thought maybe she was dehydrated she tends to stress when we are gone and refuse to eat or drink. She seems fine otherwise. Eats and drinks normally since home, playful at times.

Yesterday got home from work, fed her afternoon food and let her out noticed again the very dark brown urine. Was able to use a paper towel to dab area in yard it appears pinkish and brown. Called vet. He said no biggie she’s coming in for surgery tomorrow discontinue Vetprofen and they would check labs and urine today prior. This morning took her in they performed all those things. Urine is pretty horrible doc said lots of WBC, blood and bacteria. He wants to wait on surgery till she has been on antibiotics. Good deal.

Here’s my question though. Her labs came back with very high liver enzymes. Her liver was fine on 9/2 when they did labs prior to biopsy. Vet is stumped. Says it may be something going on with liver, doesnt want to rule out metastasis but doesn’t make sense since it usually goes to lungs first, also thinks it could have been the Vetprofen and hopefully since she’s off they will get back to normal.

He does say if it’s not then we may have to do a liver ultrasound to see if there is something going on, and if so amputation plan may have to be revised because if it’s gone to her liver there isn’t much else we can do.

Has anyone ever had experience with Vetprofen or liver problems in newly diagnosed pups with clear chest X-rays? I’ve been researching like crazy of course but could use some been there done that wisdom. Thank you so much!