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Monoclonal antibody treatment for Arthritis
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London, UK

Member Since:
15 December 2015
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16
2 July 2021 - 4:35 am
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Thanks so much, Micelle, Rene, Sally...

Michelle, yes, I'm delighted with how she's doing. She's such a high energy dog that things get quite difficult to manage if she is very limited physically. Hopefully the pounds will come off and that will help her further. (and we're not discussing me either smiley2)

Rene, glad you enjoyed the video. It's lovely to see her so happy on the beach. BTW the wet you can see in the first video is not because it had been raining (for once...) but because I had to spray her buggy down to get all the salt and sand and sea water off it. We can't have the Mega Wagon going rusty. Re her age, she's been with me 11 1/2 years now, and she was at least a year when she came to me, probably more like 18 months, but I do agree she doesn't look (or act) her age. And yes, I hope this treatment will cross the pond too. The way people are raving about it here, I would imagine that there must be plans to license it in the US and Canada.

Sally, thank you. I'm pleased she seemed less stiff to you, and this was after a whole day on the beach! Frankie is welcome here ANY time, but I know you couldn't bear to be without him. Guess you and Myrtle will just have to come too icon_lol

Meg, Clare and Angel Pie xxx

Ruby, Staffy, born June 2022, became a Tripawd, November 2023, adopted January 2024.

Also Angel Tripawd Meg (aka The Megastar), who died in April 2023, aged 14, after seven glorious years on three, and Angel Staffies Elsie Pie and Bille. In the pawprints of giants...

The Amazing Adventures of Ruby Sunshine

My Life as a Megastar

On The Road


Member Since:
24 September 2009
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2 July 2021 - 2:50 pm
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Meg has reached so many milestones and achieved so much for a dog who supposedly wasn't a good candidate for amputation. HAH! She fooled them.

I was at a vet conference in 2018 when this therapy was presented in a few sessions about emerging therapies. I sure hope it gets here soon!

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

The Rainbow Bridge



Member Since:
25 April 2007
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13 May 2022 - 8:02 pm
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megstamum said
This is a brand new treatment for arthritis which has just been licensed in the UK and EU and is showing extremely positive results in some dogs. It’s called Librela and I understand that a version for cats is shortly coming out too. It’s a monthly injection which inhibits the inflammatory process in the joints. Meg will be starting treatment shortly and I will report how we get on. 

More info here: https://todaysv.....-approval/

and also a video showing how it works

https://players.....r7LdduYCk0

  

It's here! The new monoclonal antibodies arthritis treatment for cats is called Solensia here in the States. Just heard about it this week. Here's a link to the Zoetis Petcare Solensia website for more info.

The medication insert states that:

A 112-day, masked, randomized, controlled field study was conducted at 21 U.S. veterinary clinics.

The study enrolled 275 client-owned cats with clinical signs of osteoarthritis (OA) confirmed by radiography and orthopedic examination; enrolled cats weighed 2.5 to 11.4 kg and were 1.6 to 22.4 years old. The enrolled cats were randomized to treatment with SOLENSIA (n=182) or vehicle control (n=93), administered subcutaneously on Days 0, 28, and 56.

Cats were dosed with SOLENSIA (frunevetmab injection) or vehicle control based on body weight (2.5-7 kg cats received 1 mL, 7.1-14 kg cats received 2 mL).

The primary outcome measure for success for the control of pain associated with OA was comparison of the owner’s evaluation of CSOM at Day 56 compared to baseline (Day 0, before treatment). Treatment success was defined as a reduction of at least 2 in the total CSOM score at Day 56 compared with the score at baseline.

Cats that had an increase in any individual CSOM activity score (regardless of the total CSOM score) or that received rescue analgesia prior to Day 56 were considered treatment failures. Secondary outcome measures included the total CSOM score on Days 28 and 84; Owner Global Assessments on Days 28, 56, and 84; and total orthopedic pain score completed by the veterinarian on Days 28, 56, and 84. For the Owner Global Assessment, success was defined as an owner’s impression of the response to treatment as Good or Excellent (versus Fair or Poor). Success was not defined for the veterinary-assessed total orthopedic pain score. The proportion of cats considered treatment successes based on the owner

CSOM assessment and the Owner Global Assessment was greater in the SOLENSIA group compared to the control group for all assessments. The mean total orthopedic pain score was lower in the SOLENSIA group compared to the control group at all post-dosing assessments.

Twenty four of the Solensia cats had vomiting as a side effect, the most common. Others are listed on the insert. I think I would feel good about giving this to my own cat if I had one.

This new medication is a huge victory for feline pain control! 

The Rainbow Bridge



Member Since:
25 April 2007
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22 June 2023 - 9:43 am
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Just want to let folks know that this therapy is now finally available in the US, under the brand name of Librela. See:

https://news.zo.....fault.aspx


Member Since:
16 October 2012
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22 June 2023 - 9:54 am
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great news

sassymichelle-sm.jpg

Sassy is a proud member of the Winter Warriors. Live long, & strong Winter Warriors.
sassysugarbear.tripawds.com
07/26/2006 - Sassy earned her wings 08/20/2013

05/04/2006 -  Bosch, Sassy's pal, earned his wings 03/29/19  fought cancer for 4 months.

"You aren't doing it TO her, you are doing it FOR her. Give her a chance at life."


Member Since:
16 October 2012
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5 August 2023 - 9:11 am
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Yes, just found out the Librela will finally be available in Sept or Oct of this year for it.  Jasmine will be going on it.  Our vet just said they are training the Drug Reps now.  Jamsine has severe arthritis in her back and they think this will help.  Also she told us (mom and I) that it has been available for cats for over a year here in the US and our clinic has at least 40 cats on it.  They have seen great things with it.  Dr. Rock-Paul said she will be putting all 4 of her dogs on it when they get it in.  They signed up right away when they heard about it coming out so we should be one of first clinics to get it.  With all the great things Clare and Meg said I am hoping it helps Jasmine.  🙂  When we start getting it I will send an email

 

 

Michelel

sassymichelle-sm.jpg

Sassy is a proud member of the Winter Warriors. Live long, & strong Winter Warriors.
sassysugarbear.tripawds.com
07/26/2006 - Sassy earned her wings 08/20/2013

05/04/2006 -  Bosch, Sassy's pal, earned his wings 03/29/19  fought cancer for 4 months.

"You aren't doing it TO her, you are doing it FOR her. Give her a chance at life."

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