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Research behind bisphosphonates for feline bone tumors is sparse. But while searching for palliative care pain management of feline bone cancers, I came across this one study about bisphosphonates for cats with limb cancers.
If you find others please add to this discussion.
Pamidronate Disodium for Palliative Therapy of Feline Bone-Invasive Tumors
This study sought to quantify in vitro antiproliferative effects of pamidronate in feline cancer cells and assess feasibility of use of pamidronate in cats by assessing short-term toxicity and dosing schedule in cats with bone-invasive cancer. . . . Pamidronate therapy appears feasible for administration in cancer bearing cats with aggressive bone lesions in the dose range of 1-2 mg/kg every 21–28 days for multiple treatments. No acute or short-term toxicity was directly attributable to pamidronate.
Tripawds Founders Jim and Rene
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