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Osteosarcoma Vaccine Studies | Treatment, Recovery and Oncology

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Osteosarcoma Vaccine Studies
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Member
Forum Posts: 56
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31 December 2017
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11 March 2018 - 8:05 pm
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I initially posted this to Casey's blog, but it was wisely suggested I post it here also.

I’ve mentioned previously that Casey is on the short list to participate in the extended field trial for Aratana’s live listeria vaccine. This study requires prior completion of amputation and carboplatin chemotherapy, and no pulmonary metastasis. Unfortunately, participating in this trial will be quite expensive, so I’ve been researching alternatives.

I’ve learned that UF (Florida) is starting a new study with their own vaccine, but for their study, the vaccine is administered concurrently with, rather than at completion of chemotherapy. Penn, where they did the initial study with the Aratana vaccine, is also testing a slightly different vaccine, but their protocol requires all phases, amputation, chemo, and vaccination be conducted at their facilities. Those with newly diagnosed but untreated dogs with osteosarcoma may want to consider enrolling in one of these studies.

Dogs are living for an average of nearly 1,000 days (and counting) with the Aratana vaccine, so this new field of research is very exciting for both our dogs and their people, as these vaccines may well prove effective in human osteo and other cancers such as breast cancer.

Exciting times!

The Rainbow Bridge

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12 March 2018 - 10:38 am
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You know it, super exciting! Thank you for sharing here.

We recently had the honor of sitting in on a member whose Greyhound got the Osteosarcoma vaccine last week at a clinic in Las Vegas. Also got to interview her oncologist, it was exciting to hear all the latest developments. Watch for this story in the Tripawds News blog !

It's better to hop on three legs than to limp on four.™
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23 March 2018 - 6:05 pm
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Hi,

Our great dane Quack just started in osteosarcoma trial at Cornell. He was first diagnosed Feb 16th 2018.  We looked into information at U Penn but the wait was kind of long to be evaluated.  We called the company that makes the drug and they are sponsoring a trial at many small oncology vets.  We looked into one vet in Malvern PA (Hope Veterinary Specialists).  We actually took Quack to be evaluated.  He qualified for the trial there but it's a double-blind meaning half the dogs get a placebo.  The vets at this practice were so nice and so helpful.  Although owners pay out of pocket for the amputation surgery and chemo there actually was quite a bit of financial compensation for participating in the trial. The compensation comes at various milestones during the trial.  We didn't want to risk Quack ending up in the placebo group.  We tried Cornell next which is actually in our backyard.   We had to wait another week to be evaluated and 2 weeks until his amputation surgery it ultimately worked out for us.  Quack qualified for the trial.  That includes confirming osteosarcoma there, not having lymph node involvement and not treatment before the trial.  The Cornell trial covers the immunotherapy vaccine but owners cover amputation surgery and chemo.  We had started a gofundme for Quack and our friends and even complete strangers helped us be able to afford his care.  It was amazing! Quack had his amputation surgery 15 days ago and his first chemo (carboplatin) 2 days ago.  When he completes chemo he begins the immunotherapy.  We are so hopeful that this will extend his life or even put him into remission.  

Livermore, CA
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23 March 2018 - 8:07 pm
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Hi Ann, welcome to the fourms! Your future posts will not have to wait for approval.

I've been following your blog about your boy Quack.

Thank you for sharing your experience here!

Karen and the Spirit Pug Girls

Tri-pug Maggie survived a 4.5 year mast cell cancer battle only to be lost to oral melanoma.

1999 to 2010

 

              Maggie's Story                  Amputation and Chemo

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23 March 2018 - 8:17 pm
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Thanks Karen!  It is so nice to be in contact with other folks and their pets who have been through this!  

Ann, Quack and Bear 

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27 March 2018 - 5:08 am
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I wish I knew about this vaccine when Eurydice was still here ...

But at least it can help others and hopefully it will be a breakthrough treatment !

Fingers and toes crossed here for all 

🐮🐮🐮😘💫✨🌟🌹

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

The Rainbow Bridge

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27 March 2018 - 10:19 am
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It was in very limited use in clinical trials here in the U.S., so don't beat yourself up. My hope is that it will be in wide release in many countries soon, so let's all keep our fingers & paws crossed!

It's better to hop on three legs than to limp on four.™
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27 March 2018 - 10:43 am
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I am very excited about the Listeria vaccine. My Doggie oncologist mentioned it to me and I will be inquiring with her if I can get Cookie on it.

We are only 11 days post op but I want to get my ducks in a row to see what the chances are of us getting to be a part of that vaccine.

Sounds very exciting and I'm hoping for the best!

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