Tripawds Three Legged Dog & Cat Forum Archives

I posted about this product about a year ago but wanted to follow up as they have had more experience with it and it appears to be a treatment that can avoid amputation.  A company (Vivos) has developed a material into which they infuse Yi-90 (A radioactive material that decays very quickly and with high energy).  At room temperature the material is a liquid that they can put into a syringe.  When injected into a warm body it solidifies in place.  Meaning they can inject a radioactive material into a tumor and it will stay in place and kill the cancer without harming surrounding tissue.  They have treated a half dozen or so dogs and cats.  All treatments significantly reduced tumor size. A few of the dogs have had second treatments when it was noticed the tumor had returned (from this they have learned better approaches for planning where to inject the material).  But most just have single treatment, stay the night at the vet, then go home with the owner for no further treatment except followup appointments. 

It is not like radiation treatment from a machine that works in low doses and has to be repeated many times over a long period.  Its a megadose of high energy radiation that doesn't emit far but where it does emit is lethal to cancer.  A sheet of syran wrap or latex glove will protect a person from it so it doesn't require hazmat suits for either the doctor or patient.  The only side affect so far has been ulceration of tissue because of the speed with which the radioactive tissue is killed that has to be managed to insure infection doesn't set in. Treatment is very expensive.  In fact, I would call it prohibitively expensive.  But the company has started subsidizing treatment (I don't know to what extent) because they want to generate data to convince the FDA to let them begin human trials.  

They tweeted about their latest patient  (<a href="

The tumor for our recent #IsoPet therapy was very large and took 60 injections. We are working to prevent the amputation which was prescribed. We know that early detection is the key to success, but in this case we're all hoping for the best. #radiogel #tumor #petcancer pic.twitter.com/cwFgfNFndq

— RadioGel® (@RadioGel) July 3, 2020

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The tumor for our recent #IsoPet therapy was very large and took 60 injections. We are working to prevent the amputation which was prescribed. We know that early detection is the key to success, but in this case we're all hoping for the best. #radiogel #tumor #petcancer pic.twitter.com/cwFgfNFndq

— RadioGel® (@RadioGel) July 3, 2020

) this morning.  I sure hope they can save the little dogs leg, but mostly I'm glad that the tumor has been treated and the cancer is dying.  Each dot on the tumor corresponds to where they injected the IsoPet (what they call their product).  I expect they will be sharing information about this patient in the future.  Only one of the other dog owners who got treated shared information on their treatment experience.  That dog has not had its cancer return and is doing great two years out (https://www.fac.....221/posts/).  Its tumor was much smaller than the one recently treated (maybe walnut sized).  

If your pet has a solid tumor that an injection can access (i.e. relatively close to surface of skin) and you live near Eastern Wa Washington or Kansas City Mo it may be worth checking with the company.  They are especially interested in being able to treat tumors before any surgery is performed (all dogs treated so far have had surgery(s) which failed and the tumor came back before owner resorted to radiogel) to illustrate it is a viable and in some cases preferred treatment over surgery (because it can be put exactly where tumor is regardless of how close that area is to other healthy tissue).  Because of that I think that cases that have not yet had surgery would have a higher likely-hood of being selected to be done under subsidy.