I just caught up with your posts.  My 12 year old pup Maggie had a front leg amputation 1 month ago and like everyone else here has said, it's a roller coaster but with a huge light at the end of the tunnel.  I promise that Girlie isn't as worried as you are, and you will both eventually find a new 'normal' and adjust.  It took about 3 weeks before I felt I could relax and not worry about Maggie constantly.  As you had asked, I stayed home from work for 3 days + a weekend, and then left for just 3 hours at a time and worked from home in the afternoons for another week, and am now back to my normal work schedule with going home to check on her/let her out on my lunch break.  As long as she's in a safe location you'll get a feel for when you can start leaving her alone a bit at a time.

So glad that surgery went well, and I agree completely that the incision site is an adjustment.  It took about 2-3 days before I could look without feeling squeamish.  For my sake and my kiddo/his friends who might be traumatized seeing it, we kept a t-shirt on her for the first 2 weeks.  As others have said, the pain medication can be to blame for a lot of weird behavior and restlessness, but that will taper off after the first couple of weeks and little by little she'll perk back up.  If she is eating and peeing you are doing great!!  Maggie had to be coaxed to eat, and it was a nightmare getting her to take all those pills for the first 3-4 days!  I actually had to call my vet for more tramadol because I "wasted" so many shoving them into different treats that she wouldn't eat, and they would turn to mush.  Our vet completely understood, apparently this is a common problem - and hearing that even made me feel better.  Peeing and pooping was a whole other story...a messy story that happened all over our living room.  But we survived!!  Thank you, Rug Doctor. 

I hope you have an easy way for Girlie to get in and out of the house.  Maggie is still wary of steps and we have 3-4 steps out the front and back of our house.  Thankfully she started using a homemade ramp and that improved life greatly when she could go out without a big production of coaxing or carrying her down the stairs.  As Girlie starts getting up and around more, having carpet anywhere she needs to walk will really help.  Something else I recall that may relate to others - after day 3 when the patch came off and she wasn't so restless at night she slept A LOT - that worried me but I think it was just in response to not really sleeping soundly while on the heavy medication for the first couple of days. 

Hang in there, and keep checking back here for support and advice - it's what saved me 100 times during our first few weeks after surgery!  We seemed to go two steps forward and one step back, through Maggie's recovery.  But as crazy as it all seemed at the time, it's all ancient history now and we are back to doing normal dog stuff.  It will get easier!  Hugs to you both!

Cindy and Maggie