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Right hind leg amp, share your experience and advice please!
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2 August 2024
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2 August 2024 - 11:24 am
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Hi everyone. Our 3 year old Goldendoodle, Daphne, had her right hind leg amputated for suspected osteosarcoma on July 19th. While we are shocked and devastated by this development in our otherwise healthy baby, we have acted quickly in hopes of giving her the best quality of life and potentially more time with us!

Following surgery, she was sent home with Codeine (30mgs) and Gabapentin (300mgs), with last doses of each given on Sunday, July 28th. She's still taking Rimadyl (75mg) daily with food. She was 70-75lbs before surgery.  

Daph's recovery was going as well as I think we could hope for up until about 2-3 days ago when she became more hesitant to move, and started exhibiting signs of discomfort and pain. We're worried it's some kind of nerve or phantom limb pain. 

She started to present symptoms on Wed 7/31, but we just associated the new whining with "growing pains" of trying to lay in different positions or experimenting with sitting on her bum again. We also thought we may have just startled her while sleeping with the reaction being due to some residual anxiety. This happened once or twice throughout the day, then increased in severity and frequency overnight into Thurs 8/1. 

On Thurs 8/1, we called the surgeons office for some advice. Unfortunately, we were told the surgeon won't be back in the hospital until next week but that a message would be sent over in case she can get back to us beforehand. They recommended we check with the primary Vet, who is also out until next week. Talk about bad timing! We have been very happy with the service and support of both teams throughout the chaos of the last few weeks, so I'm not complaining about their time away. Just makes it harder for us to get some immediate answers for our sweet girl. It's killing us to see/hear her struggling so much!  Luckily, another vet in the primary's practice was able to get back to us same day and recommended we get her back on Gabapentin, 300mg every 12 hours.  We started this dosage immediately at 4pm yesterday and have continued per the vets recommendation. 

Overnight into today, Fri 8/2, episodes have become less frequent, but so has movement. She had probably her worst exhibition of pain around 4am, and practically screamed "bloody murder" when readjusting on her bed. This morning she hesitated to get up and when she did, whimpered for a few feet before laying back down. She's not very interested in her food today, that's a somewhat normal thing for her. She did eat a treat we offered so we aren't concerned about her appetite at this point. 

We called our primary vet practice again this morning. They recommended moving the Gabapentin up from every 12 hours to every 8, so we are implementing that today and will see how she responds. We asked if she should take anything additional, but they didn't have a recommendation. They said they could try to call the surgeon to see if a fentanyl patch is needed, but we don't want to put her through another round of narcotics if we can avoid it. Not to mention, the surgeon is about an hour away and we worry about taking her anywhere in this state if we don't have to. Said we could also try pet ER, or wait to see how she responds to the accelerated doses and potentially fit her in at the vet's office tomorrow if there is no change. So, that's where we are for now. 

A few other things to note: 

  • The vet reviewed images of her incision and said it was healing well, with no signs of infection. 
  • No vomiting. 
  • Daph seems to be more tense overall and movements seem more frantic/panicked. 
  • We've also noticed an intermittent and slight twitching around the amputation site. 
  • Daph doesn't seem to be itchy or even interested in her wound site. She doesn't attempt to get at it or lick it. She does sometimes lick her front paw where IV was done, but that's not excessive and seems normal. 
  • To this point, has had no obvious pain response when rubbing or massaging the amp site (which we have tried to implement to help the pain per some great posts on this site!) 
  • She responded well to a cold compress in the 2-3 days right after surgery. Should we try those again? 
  • What else can ew try to help calm any emotional or psycological stress she may have? we're keeping her in a quiet, clean environment with no stairs or obstacles and various supportive dog beds. 

Is this phantom pain ? If so, is it normal at this stage and how long can we expect it to last? 

We just hit the 2 week mark and can't help but feel discouraged by this set back, though we realize that every dog recovers differently and we find comfort in that. At the same time, want to ensure we're doing all we can to properly treat and heal her!  

Daph is scheduled for her follow-up/suture removal with the surgeon on Tuesday 8/6 and then to see a doctor in Internal Medicine & Oncology on Wednesday 8/7 to determine her next steps for treatment. We haven't gotten the specific results from the biopsy report since the surgeon is away and plans to call us to discuss them when she returns, but she did have them sent over to Internal Medicine & Oncology when they came back and we feel that the cancer has been confirmed at this point given that Internal Medicine & Oncology called on 7/31 to tell us they reviewed her charts/results and scheduled us for the aforementioned 8/7 appointment. We're hoping we can figure out how to keep her comfortable at least until next week, as we'd hate to take her anywhere while she's feeling this way. 

Apologies this got so long, but wanted to provide as much detail as possible. We're SO grateful to have found this community! The posts have been so helpful and comforting for us over the last few weeks. 

Thank you!sp_hearticon2

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The Rainbow Bridge



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2 August 2024 - 11:52 am
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Marie, you are so good at documenting everything that's been going on!

This does sound like some type of unresolved pain, I'm so sorry she is going through this. Phantom pain is common as you know, but it's not the only kind of pain after amputation surgery. Rest assured it's not unusual but it often does need to be treated with more than Gabapentin.

pain management isn't always a one-method approach, sometimes you need to add more things into the mix like additional medication and rehab therapy modalities like acupuncture.

First, I would call your primary vet back and ask for Amantadine. Get it today. It is not a narcotic, but it works well with Gabapentin, and has made a huge difference in a lot of post-op situations. It can make her sleepy though so you want to introduce it at night, per the advice from a pain expert we interviewed.

Gabapentin every 8 hours should make a big difference and that's a good dosage. Being sleepy is not too unusual, and helpful to allow her to rest, but you want to make sure she isn't so zonked out she can't get up to eat or eliminate. It's a fine line.

Next, I would ask for a referral to a rehab therapist. It can make a huge difference in a pet's recovery as they have other modalities to minimize and treat phantom pain (acupuncture especially helps!), and the Tripawds Foundation can even pay for your first rehab visit . It's quite educational for pet parents, as these stories show. If your vet doesn't have a referral, let me know and I'll find a practice for you.

To answer your questions:

  • The vet reviewed images of her incision and said it was healing well, with no signs of infection. 

Awesome! Document the bruising and you'll see a  change over time, usually a positive one.

  • Daph seems to be more tense overall and movements seem more frantic/panicked. 

This could be pain, or it could be a result of her sensing your nervousness too. In time it will get better, especially now that you've upped the Gaapentin dosage.

  • We've also noticed an intermittent and slight twitching around the amputation site. 

Totally normal and is usually not pain related. It can often last a lifetime but doesn't hurt, it's just the nerve endings trying to figure out what to do. Eventually it will happen less and less.

  • To this point, has had no obvious pain response when rubbing or massaging the amp site (which we have tried to implement to help the pain per some great posts on this site!) 

Did you see this post about desensitizing the incision area? Super helpful, and calming for both her and you!

  • She responded well to a cold compress in the 2-3 days right after surgery. Should we try those again? 

You can try to see if it helps her feel better, just keep the sessions short.

  • What else can ew try to help calm any emotional or psycological stress she may have? we're keeping her in a quiet, clean environment with no stairs or obstacles and various supportive dog beds. 

Most of the emotional or psychological stress is all on us. Keep as calm and pawsitive as you can. Remember, dogs mirror our emotions. The more we are scared, feeling hopeless, or worried, the more they will feel it too. Our attitude makes a big difference in recovery so stay strong and lean on us! 

Let us know what your vet says about the Amantadine and if you need help finding rehab.

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5 August 2024 - 9:08 am
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Good morning! 

Thanks so much for your prompt and thorough response! We followed your recommendation and got the Amantadine from the specialist who performed Daphne's amputation.  She's been taking it along with the Gabapentin since Saturday morning and seems to be feeling much better! The screaming fits have subsided (knock on wood) and any whining is few and far between. She's moving around with ease and seems much more comfortable!

We've also noticed that a positive reaction from us helps any discomfort to subside more quickly - as you suggested! 

Osteosarcoma was confirmed on Friday evening per her biopsy results. While we're disheartened, we were told her lymph node was okay and mitotic index was on the lower side which I think gives us some hope for more time with our girl!  We want to be vigilant and pursue additional treatment options. She will see the oncologist on Wednesday. 

We're also very interested in seeing a rehab therapist, per your recommendation!  The practice we are going to does have a rehab center and we're hoping to get more information this week. But we really appreciate your offer to help us track down a referral if this option doesn't pan out! 

Thank you again for sharing your expertise! It's extremely helpful and comforting. 

Marie

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The Rainbow Bridge



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5 August 2024 - 9:56 am
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Marie this made my day! I'm so happy things are looking up! 

As you can see, achieving good pain control is often a trial and error and trial again process. I'm so happy the Amantadine is working. 

Very cool your clever has rehab! What practice are you going to?

Im sorry about the osteosarcoma diagnosis. Try to focus on the here and now and don't dwell on the prognosis. Remember that it's not based on Daphne's physiology and many dogs will surprise us with their longevity despite the odds! Not always but it happens.

Please keep us posted!

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5 August 2024 - 10:05 am
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That is some great advice you received.  

My dog’s story is listed in this forum under Roger’s amputation.  His back right leg was amputated on 7/1/24.   Had several set backs and complications as documented and if you will read you will see and feel my helplessness and frustration with the situation.   I point out Roger’s story for you because I think it’s just a process.  I agree I tried to be as positive towards the process in front of my dog as possible and treat him as normally as possible so as not to transfer my stress.  I am sure I still could have been better.  

However after exactly 5 weeks today from the actual amputation my dog is becoming more and more like his old self.   It’s a journey and just keep being strong for your beautiful dog.  She will come out of it and everyday you will see improvement.  There will be set backs in those improvements but just know each day will get you closer to what you want and that is your dog get back to herself.  This is all just from my recent personal experience and I hope it helps.  I know things feel grim sometimes and I completely understand.    

Good luck….keep your chin up and just keep moving forward.  It will get better and easier.  

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9 August 2024 - 11:08 am
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We take so much comfort in chatting with those of you that have been through this as well and have such valuable insight to share. THANK YOU!

We are going to Chesapeake Veterinary Referral Center located in Hunt Valley, MD. The location is comprised of several different specialty practices – Chesapeake Veterinary Surgical Specialists (CVSS) performed her surgery.  Her oncologist is in the Atlantic Veterinary Internal Medicine & Oncology group.  We’ve been beyond pleased with both!

Amy – thank you for directing us to your sweet Roger’s story! It’s reassuring to hear that not all dogs “bounce back” quickly, but that they DO adjust well to the new normal in their own time. Like you said, it is a process. And each journey is unique. We relate so much to your feelings of helplessness. You are so strong and providing such great care to your sweet boy. He is lucky to have you!  

Daphne seems to be doing well. She’s still taking gabapentin & amantadine for the pain that developed ~2 weeks post-op. Her surgeon & oncologist agreed we will keep her on them for 3 weeks to hopefully break the pain cycle, then weaning her off of the gabapentin first to see how it goes.  We are 3 weeks post-amp today and she had her first round of chemo (carboplatin) this past Wednesday! She amazes us every day.

We don’t understand most details of the path report. It confirmed her diagnosis as osteosarcoma-fibroblastic to osteoblastic, poorly productive. Mitotic count 0. No angiolymphatic invasion observed. Imaging/CT scans/Labs showed no evidence of pulmonary metastatic disease. Normal ALP.  FWIW.

We are determined to not leave any stone unturned for our girl. But we know this cancer is aggressive and factors such as her young age may work against her. We are trying so hard instead to focus on the present - how she’s feeling today and enjoying each new day together!  Every moment is truly a gift.    

We appreciate the time and kind, comforting words so much!

Marie

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The Rainbow Bridge



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10 August 2024 - 5:47 pm
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Wow Marie, that looks like such a fantastic referral center, and level of care that Daphne is getting! Lucky Dawg smiley16 How is she doing this weekend? Any signs of chemo side effects? Hope not! 

I like that the pain control will last a while longer. It should help a lot with any residual pain.

Yes, this cancer can be really mean for sure (and I still have a hard time understanding those lab reports ... that's why we pay our dogs' oncologists, to interpret them, right?) but our biggest victory against it is our attitude. You have a great one to start with and if you can carry that through, cancer will never win. Yep, every day is icing on the cake! 

Give Daphne extra belly rubs from us, she's such an incredible pup!

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Virginia



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10 August 2024 - 8:55 pm
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Hi Marie and sweet pup Daphne.  For whatever reason,I thought I had made a post adding my  support.....,apparently  not!  It clearly didn't matter as you have gotten great support, insight and information.

Yes making each day the best day evvvver and not worrying about the tomorrows is the best way to beat this crap disease.  Don't  let it I interfere with your time together NOW!  Daphne is oblivious about any path report and could care less what all that "mumbo  jumbo" says.  The bliss of being a dog, right??

I also had my Happy Hannah  on pain meds at some level for about three weeks.  Every dog is different when it comes to how much and how long they should take pain meds.  Sounds like you have a good plan underway to help her get her sparkle back..and she will!  Promise!!!. If I recall, it seems like it was about by the fifth week that I really felt like she was FULLY healed on all levels and was her Happy, joyous self.

You're doing a great job give yourself a pat on the back!

Hugs

Sally and Alumni Happy Hannah and Merry Myrtle and Frankie too!

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

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27 August 2024 - 11:48 am
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I'm sorry to have disappeared for a few weeks, it has been a busy time! Thank you all for your encouragement and support! It means so much and is so comforting to be reassured about the timeline for recovery and return of the "sparkle" being different for every doggo. 

Daph is coming along well! We feel SO blessed for the care she's received and how quickly the specialists helped us take action. It's crazy to think how much has changed since early July. 

The first few weeks were harder than I expected because so much of her normal bubbly personality had gone away and I wondered if she could ever be the carefree, PAINFREE, happy dog she once was. But over the past 2 weeks, she has been BEAMING!! Our girl's personality is shining and she's enjoying so much of the activities she always has. We are SO thankful and are enjoying every blessed day with her. 

Today she has shown signs of having developed a UTI - pending uranalysis results now. Tomorrow is exactly 3 weeks since her first round of chemo (Carboplatin) and she was scheduled to have the next round tomorrow, but that's now been pushed to next Wednesday, 9/4 out of caution.  Any experience with this kind of development at this stage, or with chemo in general? So far, she hasn't exhibited any other side effects of the chemo (thank the Lord!) so we're hoping this is maybe just a coincidence? or minor uti resulting from suppressed immunity? 

Thank you! 

Hugs sp_hearticon2

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27 August 2024 - 2:04 pm
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Hudson is 18 days post rear leg amputation. Sutures came out at 14 days. He had a couple rough days after suture removal. I assumed we would be cone free, but he cannot control his licker. So, we are back into it. The areas where his incision is thicker (not smooth) seem to worry him.

It's hard knowing if you're on the right track when every dog is so different. Plus you want to do everything just right!

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The Rainbow Bridge



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27 August 2024 - 5:46 pm
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WOOHOO! Daphne is a SUPERSTAR! smiley10 Thanks for letting us know, and there is no need to apologize for being away. You have your hands full right now. She's the #1 priority and we are just thrilled that life is so much better. 

Has she had UTIs before? It's probably just a coincidence regardless, as far as I know suppressed immunity isn't a cause, but bacteria is (but then again I'm not a vet so FWIW). Don't panic though, you've got this under control and being looked at by her awesome team. Glad they caught it right away if that's what's going on.

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