I am starting this thread in the hopes that one day another kitty mama will need some information on metronomics in kitties, specifically for osteosarcoma.

A brief background (I'll try to keep this brief):

OSA in kitties does not spread as rapidly as it does in dogs, so in almost all situations, when a kitty gets OSA, they amputate the leg and that's it.  No chemo of any kind is recommended.  Jill's case, however, presented differently.  Her primary tumor was in her toe and her toe was amputated (upon amputation, clear margins were achieved, so no further treatment was recommended.  6 months later, however, a met appeared under the skin (not in any bone) in that same leg.  So, we know Jill's case spreads more rapidly than it typically does in a cat.  Her leg was then amputated as we all known and then she was treated by four rounds of IV chemo (2 rounds of carbo, 2 rounds of doxorubicin, alternating the two).

Since I have learned so much about metronomics on this site, I brought it up to her oncologist, and we decided to give it a try.  Jill's bone marrow has had a rough time bouncing back from the IV chemo, it is now 12 weeks later and her white blood cells, specifically her neutrophils, are still on the low end.  We know from CBC's done prior to chemo that she has naturally low neutrophils, but they are still lower than "Jill normal".  Since this is the case, instead of cytoxan (Cyclophosphamide), which many with OSA are treated with metronomically, Jill will be taking Leukeran (chlorambucil).

So begins our journey part 3.  She will be given a 1mg capsule daily of Leukeran for 6 months.  Each month, she will have an exam and blood work done to test her white blood cells.  It has been so frustrating for me up until this point, yet I do understand, that there is no research done and I have no information on metronomics on cats.  I do understand and agree that money needs to go into researching diseases that affect more animals - why spend the money on this when it appears that there is just this one cat that needs the background information.  So I get it.  However, I would have loved some comfort going into this knowing that this will be helping her and she will handle it well.

So, here is to Jill being a pioneer and here is to hoping that one day, our journey will help some kitty mama!  

"Hmmm....what is this and what are you planning to do with it????":

http://i1289.ph.....6123cd.jpg