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Interesting study published about scientists who researched the effectiveness of metronomic chemotherapy :
Evaluation of metronomic cyclophosphamide chemotherapy as maintenance treatment for dogs with appendicular osteosarcoma following limb amputation and carboplatin chemotherapy
OBJECTIVE To determine the effectiveness of metronomic cyclophosphamide (MC) chemotherapy (primary treatment of interest) with adjuvant meloxicam administration as maintenance treatment for dogs with appendicular osteosarcoma following limb amputation and carboplatin chemotherapy.
CONCLUSIONS AND CLINICAL RELEVANCE Maintenance MC chemotherapy following limb amputation and completed carboplatin chemotherapy was associated with no increase in PFT or OST in dogs with appendicular osteosarcoma. Cystitis was common in MC-treated dogs, and prophylactic treatment such as furosemide administration could be considered to reduce the incidence of cystitis in such dogs.
This article about metronomics was published shortly after the 2018 American Veterinary Medical Association conference
July 16, 2018
Chemotherapy offers pets with cancer the ability to live longer with better quality of life despite having a terminal disease. However, traditional chemotherapy protocols are not the right fit for every owner, patient, or disease process. A newer option called metronomic chemotherapy offers an alternative treatment, explained cancer specialist Sue Ettinger, DVM, DACVIM (oncology), at the 2018 American Veterinary Medical Association Convention in Denver, Colorado. READ MORE