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Caring for a Three Legged Dog or Cat

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Primor antibiotic okay with low WBC count?
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Rock Hill, SC
Member Since:
28 November 2011
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24 May 2012 - 7:27 am
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Hi Pam.  I have a call in to our vet, but today is his surgery day and it might be awhile before I hear back so I thought I would give you a try before Zeus' next meds are due.

History: Zeus (11.5 yr old husky, six months post amp, last/sixth Carboplatin was given on 5/4/12) got very sick on Tuesday - three incidences of gag/cough, very lethargic.  Took him to the vet and his temp was 105.5 and x-rays showed a bit of cloudyness in the chest.  CBC showed that the WBCs were bottomed-out.  Vet said the chemo likely deplinished the WBCs which allowed him to get an infection, probably pneumonia based on the x-rays but could just be a systemic infection.  They kept him overnight on IV antibiotics and fluids and I picked him up yesterday afternoon.  They gave him an injection of Convenia and sent him home with 14 days of Primor 600 mg to be taken once per day.

Question:  Not familiar with Primor so I looked it up and PfizerFrank's online information specifically says:

"Primor® should not be given to dogs that

    ...

  • Have low blood cell or platelet counts"

    ...

Should I be concerned about giving him this since his WBCs were so low?  Thanks!

Zeus was a Husky mix diagnosed with Osteosarcoma at age 11.  A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/



Member Since:
22 August 2008
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24 May 2012 - 5:49 pm
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In rare cases sulfa drugs like Primor can cause bone marrow suppression and decreased white cells counts.  This is more common in certain breeds such as Dobermans.  The sulfa drugs have a very good spectrum of activity against most bacteria so are therefore often given by oncologists if the white cell count is low due to chemo.  I would be more concerned with the Convenia injection since it does not have a very wide spectrum of activity and once given stays in the body for 2 to 3 weeks.  I usually give Baytril IV and then tablets orally after a dog's WBC count crashes especially if there is pneumonia but the Primor should provide good coverage.

Pam

Rock Hill, SC
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28 November 2011
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24 May 2012 - 6:26 pm
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Thank you, Pam.  I really do appreciate your guidance!

Lisa

Zeus was a Husky mix diagnosed with Osteosarcoma at age 11.  A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/

Las Vegas, Nevada
Member Since:
14 August 2009
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24 May 2012 - 11:42 pm
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Lisa,

I'm glad I'm not the only one that googles every med given to the dogs!  It's good to be safe!

Her Retired AvatarComet - 1999 to 2011

She departed us unexpectedly  January 23, 2011 at the age of 12 1/2.

She was born with a deformed front leg and a tripawd all of her life.

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