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no vaccine for simon
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18 June 2018
4:40 pm
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Bucketeers
Forum Posts: 6646
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21 May 2016
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Hi Luke 🐾

Just got this quick email from Eurydice's vet:

Cyclo is more common to use and to this day there are no advantages of doing clorambucil except in selected cases that don't do well on cyclo.
Best regards,
😘🐮💫✨🌟🌹

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

18 June 2018
4:42 pm
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Thanks. Much appreciated

18 June 2018
4:43 pm
Virginia
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Bucketeers
Forum Posts: 24581
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eurydice said
......... I know he keeps her in his heart and is touched by the fact she somehow is still helping others.

Eurydice  touches our heart and helps us in every way in every day...always will, always has.💖💖💖💖💖

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

18 June 2018
4:45 pm
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Bucketeers
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ohhhhh ... slobbery kisses blowing down 💕🐮💫✨🌟🌹💕 from the sky for both of you 🐾

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

18 June 2018
10:48 pm
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trying to understand the vaccine advantage

  I read something that directed me from dr ettingers page..to one of the vet journals??

  50% live 3 yrs or more with the vaccine

  80% die in 2 yrs without the vaccine

Did I get this right? 

19 June 2018
2:48 am
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Bucketeers
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Hi Luke 🐾

I will try to call Eurydice's vet today to ask further info on thalidomide, lomustine plus your questions reg the vaccine. 

Will come back to you as soon as I speak to him.

Hugs and cuddles 😘🐮💫✨🌟🌹

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

19 June 2018
5:55 am
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Bucketeers
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Hi Luke 🐾

Had a long talk with Eurydice's oncologist just now, here's what he said:

1. Thalidomide - Drug was designed to be used in pregnant women originally, he has no experience using this drug in dogs.

2. Lomustine - this is a pure IV chemo drug. 

Normally, the first choice (because it causes less side effects, its is safer and there are more studies published) is carboplatin, second choice is doxorubicin and third choice is lomustine.

All three are classified as first line chemo treatments.

Lomustine is usually considered if there are significant side effects with one of the other IV chemo (or both) or if they do not work with the specific animal. 

Also, it can be used to provide rotation of IV chemo drugs hence avoiding resistance building up.

Sometimes oncologists prescribe a combination or carboplatin and doxorubicin in separate sessions for that same purpose (I believe that was the case of Manni in Germany, if my memory is not failing me). 

Lomustine is also used in paliative care, ie when metastases are present or the patient is terminal. 

In these specific situations, lomustine will be administered as metronomics , ie the high dose is reduced and administered as a series of smaller doses at different times of the day, adapted to the specific dog's case.

3. Aratana vaccine - it is not known in Portugal.

Luis Cruz got really excited about this vaccine trial, he is aware of Aratana, they are cut edge in research, so he is all ears!

I told him we will keep him informed as progress is made and as we get feed back from our tripawdian dogs (within what is acceptable to share because of confidentiality clause, of course)

Regarding Simon, he said if he had been in his hands for cyberknife he would have offered to extract 5mm of the affected bone whilst he was under anaesthesia for radio.

His opinion is there is virtually no chance of a positive biopsy now because he has had treatment so he thinks a biopsy at this stage will be inconclusive.

He said he does not understand why a positive identification of osteosarcoma via xray is not accepted because as long as it is sufficiently advanced there are no doubts it is in fact osteo.

This could be just a legal requirement in which case there is no way around it ? ...

Hugs and cuddles 😘🐮💫✨🌟🌹

 

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

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