Tripawds Three Legged Dog & Cat Forum Archives
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12:52 pm
Team Tripawds
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25 September 2009
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Very exciting news from the University of Minnesota's Veterinary Oncology Team:
A new study published in the Journal of Biological Chemistry has found bone tumors have preprogrammed genes, meaning the genes of the cancer remain unchanged even after a tumor is found in the body.
These findings resulted from research conducted on both canine and human bone cancer cells at the University of Minnesota College of Veterinary Medicine, Medical School, and the Masonic Cancer Center, University of Minnesota. The project was conducted by Milcah Scott, Hirotaka Tomiyasu, D.V.M., Ph.D. and Aaron Sarver, Ph.D. It was directed by Jaime Modiano, V.M.D., Ph.D., professor in the Department of Veterinary Clinical Sciences, and Subbaya Subramanian, Ph.D., associate professor in the Department of Surgery.
What they found
Researchers discovered a mechanism responsible for creating the gene signature and the resulting tumor behavior. The findings support the idea the behavior of bone cancer is programmed in each tumor when it forms and that program remains unchanged through disease progression.
READ MORE: http://www.heal.....ne-cancer/
Tripawds Founders Jim and Rene
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1:13 pm
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17 October 2012
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That is awesome news. I hope more is found on this and that a cure is on the way
xoxoxox
Michelle & Angel Sassy
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Bucketeers
22 February 2013
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Did I read the article right?? It does not matter how long the tumor jas been in the body, it does not change the aggression?? Basically, that's already pre- programmed? I'm sure I'm misunderstanding it. Otherwise, all the worry about "early detection" and amputation asap has no bearing on progression??
Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!
1:13 pm
Team Tripawds
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25 September 2009
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Good point Sally, it makes you wonder. Unfortunately that's what I got out of it too. Maybe one of our more scientific-minded members can give us their insight?
The thing about bone cancer is, the longer you wait the more painful it gets, so amputation asap is still critical no matter how the tumor behaves.
Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet
jerry said
Good point Sally, it makes you wonder. Unfortunately that's what I got out of it too. Maybe one of our more scientific-minded members can give us their insight?The thing about bone cancer is, the longer you wait the more painful it gets, so amputation asap is still critical no matter how the tumor behaves.
I am definitely not one of those scientific-minded members so no insight to offer...but I too got the same read from the article. And, yes, the horrific pain of bone cancer leaves little choice but asap amputation. However, this finding may well explain why some dogs sadly only get a few months post amp, while others get so much longer. Hopefully, somehow, this new info will lead to better treatment individualized in intensity depending on the signature of a particular dog's tumor.
Sketch's Mom
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