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6:40 pm
28 November 2011
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For chemo, our vet does two hours of fluids, chemo (carboplatin) administration then one more hour of fluid. All that fluid added up and Zeus had an accident in the lobby before I could pay and get him outside. Unfortunately he managed to get some urine on his foot where it was puddling on the floor. I took him straight home and washed his feet, but now, one week later, the skin between two of his toes is red and raw and he is just fighting us to lick it. I'm guessing it is a burn from the chemo. Is it safe to use Neosporin on the burn?
Thanks!
Lisa
Zeus was a Husky mix diagnosed with Osteosarcoma at age 11. A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/
9:01 pm
14 August 2009
Offline
Poor Zeus!
I'm not a vet...if you haven't noticed 
so I won't even venture to guess what you can and can't do!
Comet - 1999 to 2011
She departed us unexpectedly January 23, 2011 at the age of 12 1/2.
She was born with a deformed front leg and a tripawd all of her life.
3:46 am
4 May 2012
Offline
Hi, I don't have an answer for this either but would love to know just in case my girl has the same problem when she goes through chemo soon. Does anyone know the half-ife of carboplatin? Does it stay for a long time in the environment if excreted? Maybe there is another cause for the redness? Could Zeus be licking it when you're not looking? Hope it gets better soon
Amy and molly
9:31 am
Team Tripawds
Administrators
25 September 2009
Offline
Oh Poor Zeus!
As for neosporin, Dr. Pam said in this post:
I have never had a problem using Neosporin on dogs although I tend to prefer Silvadene because it absorbs better and has a better spectrum of activity. Do not use an ointment on the incision until the sutures are out unless your vet tells you otherwise since it may delay healing or affect absorption of SQ sutures.
Pam
I'm sure Dr. Pam will be here soon to address Zeus' issue specifically, but meanwhile here is what Wikipedia says about carboplatin's absorption:
Carboplatin is less potent than cisplatin; depending on the strain of cancer, carboplatin may only be 1/8 to 1/45 as effective. The clinical standard of dosage of carboplatin is usually a 4:1 ratio compared to cisplatin; that is, for a dose that usually requires a particular dose of cisplatin, four times more carboplatin is needed to achieve the same effectiveness. The stable property of carboplatin is a mixed blessing: once uptake of the drug occurs, its retention half-life is considerably longer than cisplatin, but it is also this inertness that causes carboplatin to go right through the human body, and up to 90% of the carboplatin given can be recovered in urine.
It's possible it could be a burn, so call your vet and find out, then report back here when you can, I'd love to hear what they tell you. Good luck. Give Zeus a smooch from us.
Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet
12:24 pm
28 November 2011
Offline
Thanks everyone. I just heard back from Dr. R and I'm going to pick-up an antibiotic ointment this afternoon. He said they haven't ever had a problem with chemo burns but said it could be possible if he were just really sensitive to the chemo compound.
To give a bit more detail in case anyone else encounters this problem, a few days after his 3rd chemo we noticed a small (pencil-eraser size) raw spot right below his bottom lip. It healed up but then another one appeared a few days after his 4th treatment. At that point we put two and two together and figured out it was where he would lick his privates after going to the bathroom. After treatments 5 and 6 we became diligent about wiping any remaining driplets before he could lick and that seemed to do the trick.
However, after four hours of IV fluids during the last chemo, he was asking to go out right as they came in to unhook him. I thought I would have time to pay and get him outside but when we got to reception the lobby was full and there were about four other people checking out. Instead of taking him out and coming back in, I just stayed in line (BAD mom) and he just couldn't hold it anymore. As he peed, it puddled on the floor and seeped under his rear foot. I know they make a big deal of not touching the urine/vomit/poop for several days due to the drug excretions. Instead of asking if I could take him back and wash his feet, I just hurried home and washed them at home (BAD BAD mom). I guess that allowed the chemicals to stay there long enough to burn...
Zeus was a Husky mix diagnosed with Osteosarcoma at age 11. A visible lung met and suspicious spot on his liver meant a poor prognosis-six weeks was our vet's best guess. We decided to fight for our boy and his right front leg was amputated on 12/1/11. We did six rounds of chemo, changed his diet and spoiled him completely rotten. We were blessed with 10 great months after diagnosis. Against the odds, the lung met remained a single met and grew very little over those months. A wonderful furbaby with the most gentle spirit, he fought with a strength that we never imagined he possessed. We have no regrets...
http://zeuspod......pawds.com/
