Tripawds Three Legged Dog & Cat Forum Archives
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Hi Doc,
How often is a metronomic protocol recommended after amputation for a Grade III STS? Both the FNA and chest radiographs showed no evidence of mets. Not sure yet (until tumor is sent off post-op) exactly *which* STS we're dealing with. I did ask Shelby's surgeon and she said since oncology wasn't her field of specialty, she was hesitant to answer. Shelby's RF leg will be removed Friday.
Thanks in advance!
Metronomics can be used for any soft tissue tumor (sarcoma) although it is most often used for osteosarcoma and hemangiosarcoma. I would consult with an oncologist to see if they would want to start ASAP versus using a stronger drug first and saving the metronomics for later.
Pam
Thanks for answering so quickly Pam, we were wondering about this. Good to know!
Tripawds Founders Jim and Rene
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Thanks so much Doc for the quick answer! Unfortunately, she is merely my foster dog (much loved, I might add) and as such, any decisions for treatment, appointments, referrals and all that good stuff must be approved by the rescue's BOD. I will certainly (ahem) *urge* them along as best I can.
If I may ask another question, are there results from studies showing longevity/life expectencyusing the protocol versus doing nothing? I recognize that each dog is different....this is my 9th trip down Cancer Road.....but if I can present actual statistics showing prognosis with the protocol rather than without it, it might help.
Again we thank you so much!
Metronomic chemo is so new that many of the studies are still ongoing. There are some papers in the works but I'm not sure if any of those would help with your dog's tumor type. Oncologists don't even agree on which drugs work best since we are still in the trial and error phase (some use cyclophosphamide while others might prefer CCNU or Leukeran). Your best bet is to have your primary vet or oncologist write you a letter for the foster group.
Pam
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