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Hi - Is it safe to give carprofen to a dog who is doing carboplatin chemo?
Just wanting a second opinion here on this as I noticed on the VCA fact page about carprofen that it shouldn't be given if the dog has low platelets, which she does right about now between chemo rounds (e.g. PLT 62 on her last round), and I noticed it also shouldn't be given with nephrotoxic medications and I believe carboplatin may be one.
Our rehab therapist found a bit of moderate back pain in Juno and we thought to get it under control with some meds while she rebuilds her strength. I took her to our regular vet to ask about prescribing something for the pain and he gave us gabapentin and said that he'd write a script for carprofen too, but first wanted us to ask Juno's oncologist if that would be safe. The oncologist got back to us and said it would be okay. However, given our primary vet's hesitance and seeing what I did on the VCA fact sheet I wanted to get a second opinion.
Also, I am planning to get her in for some acupuncture and chiropractic work for this back pain, so we may have other avenues to treat it if the carprofen isn't safe while she does chemo.
Thanks for your thoughts -
Natalie & Juno (aka June)
I think a short course of carprofen would be okay as long as her kidney enzymes are normal. My dog Tazzie always had low platelets after her carboplatin and she was taking meloxicam which is also an NSAID like carprofen and she did fine.
Pam
Great question Natalie! And what an eagle eye you have to find that info! Good job!
I wonder if Galiprant (https://tripawd.....pawd-dogs/) has those types of warnings?
I'm looking forward to Dr. Pam's response.
Aww. Thanks. 😊 Interesting - thanks for pointing Galliprant out, @jerry.
My VCA cheatsheet on Galliprant does seem to suggest it has far fewer interactions and risks compared with carprofen. Could be promising.
I'll be interested to hear Dr. Pam's persoective on that one too.
Natalie & Juno (aka June)
"Dr Pam did respond
I think a short course of carprofen would be okay as long as her kidney enzymes are normal. My dog Tazzie always had low platelets after her carboplatin and she was taking meloxicam which is also an NSAID like carprofen and she did fine.
Pam
Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!
I think any NSAID is okay as long as the dog can stomach it without vomiting and as long as the kidney enzymes are normal. Galliprant is less likely to upset the stomach and may be safer on the liver and kidneys.
Pam
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