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Should I start metronomics??
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10 July 2018 - 3:18 pm
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Why aren't I calling my vet asking for the metroninic drugs?

  Simon had a ct on Friday which showed no lung mets..  He had 6 chemo treatments as well.

Are there members here who did the amputation.. had the 6 chemo treatments and then did NOT do the metronomic program... ie  CYC cyclophosphamide  plus an nsaid like piroxicam.  

I'm not sure why I don't have the sense of urgency to start this program. Usually I want to do things immediately. and aggressively.  How important is metronomics in my scenario?  ie  assume the cancer hasn't spread and there is no cancer left to spread??  

The Rainbow Bridge

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10 July 2018 - 4:06 pm
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I'm sure there are some members out there who didn't do it after chemo, so hopefully they will chime in.

As for its urgency, that's entirely up to you, Simon and nobody else. Do what feels right and what you can afford, that's the best medicine there is.

It's better to hop on three legs than to limp on four.™
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10 July 2018 - 6:19 pm
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We planned to do metronomics with chemo, but when the vaccine study required no metronomics , we held off.  We now have Casey on metronomic therapy.  We have not done chest X-rays as honestly, we don't know what we'd do differently if we knew about mets.

Has anyone had real success with Palladia?

Here and Now

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10 July 2018 - 7:55 pm
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Don't miss this informative Tripawds News blog post about metronomics and visit any highlighted metronomics link for many more blog posts and forum topics on the subject.

Metronomic Chemotherapy FAQs for Tripawds

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10 July 2018 - 10:46 pm
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thanks for sending me the blog on metronics.. Got me re focused on the goal..

I do like to copy what successful people are doing.

For ex:  Dr Sue rotates cytoxan  ( cyc) and palladia.

She gives the cyc in the morning and next day,, gives the palladia at nite to reduce nausea.

My nsaid will be peroxicam.  ( her to to nsaid)

Is there a way that Dr. Sue can answer these questions:?

She said she prefers leukeran but the price got so high that she switched to cytoxan.

   Would she rotate leukeran with palladia? ( as she does with cytoxan)

Dr Sue also spoke of low dose lomustine.

   At this date,, is that something that can be used in place of one of the other meds?

 Cystitis:

  I know it occurs mostly in females.. and we look for bladder irritation.. If Simon will be going to the vet onclogist monthly for zolendrontate, would it make sense that they can monitor this every month and that will satisfy the risk?  ( Simon loves to get in the car, and when I pick him up after a few hours.. he is very happy.. so this isnt a negative for his well being) 

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10 July 2018 - 11:27 pm
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luke4275 said
Is there a way that Dr. Sue can answer these questions:?

You would need to ask Dr Sue Cancer Vet, we presume that's who you're referring to...Dr Sue Ettinger and her team are not registered members of this site, and likely far to busy to respond here.

Scotland, ON
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11 July 2018 - 9:30 am
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We did do metronomics for Bruce, we did the amputation and 4 rounds of carboplatin, followed by 6 months of cyclophosphamide and metacam. The only reason we stopped at 6 months was that he was doing great, but I was worried about cystitis and decided we should quit while we were ahead - that was just over a year ago. Bruce is now at 22.5 months post amputation, we haven't done chest x-rays since we stopped the metronomics but so far he's not experiencing any type of ill health or symptoms I would associate with lung mets, such as coughing or difficulty breathing. Of course we have no idea if he's doing so well because of the treatment or just because he's one of the lucky one's who have had a great outcome so far all things considered. 

Virginia
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11 July 2018 - 9:57 am
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YAY BRUCE!!!!!  So glad you chimed in and sooooo thrilled  to hear how well that big boy is doing!!😁

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!

The Rainbow Bridge

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11 July 2018 - 10:30 am
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It's wonderful to hear Bruce is doing so well, thank you for the pupdate!

It's better to hop on three legs than to limp on four.™
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