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WYO
Member Since:
10 February 2011
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28 March 2011 - 12:03 pm
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Just an update in case someone has to deal w the MRSA in an amp also, I thought I would document:

Bud played and rolled in the grass and sunshine this weekend, I noticed Sat night that there was a red spot where he had previous skin infection. It is spreading and pussing so we went back to the vet today. He took slides and there was bacteria and white blood cells showing bacterial infection. It is probable that it is MRSA again. Bud has another two weeks of Baytril and a topical spray for the spot.

The good news was no fever, enlarged lymphnodes or other signs of infection.

His knee and the swelling in it had improved quite a bit from his previous fall. Oh and he lost another lb even with all of the ammpversary observance treats!So keep celebrating friends!!!!

Frustrating yet hopeful!!! PAWS UP!

On The Road


Member Since:
24 September 2009
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28 March 2011 - 12:08 pm
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We'll be keepin' all our paws up for Bud, for sure! Thanks for the update, please keep us posted.

Tripawds Founders Jim and Rene
tripawds.com | tripawds.org | bemoredog.net | triday.pet

krun15
18
28 March 2011 - 12:13 pm
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Well, it sounds like overall Bud is doing OK...yea for no fever or the other nasty stuff. 

Our perspective sure does change when we deal with these health issues, doesn't it?  So he has an infection again- but we are 'happy' because it isn't as bad as before!

Maybe we need a tee shirt that says 'Frustrating yet Hopeful!'.  We could leave a blank space to fill in the particular issue: sore knee, arthritis, infection, etc...

 

Thanks for posting this info- hopefully the treatment will knock down this episode of infection.

 

Karen and the pugapalooza

littlemanjake
19
28 March 2011 - 6:29 pm
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Hi,

I'm sorry you & Bud are having to deal with recurrent MRSA . MRSA infections are always difficult to treat & have a tendency to recur repeatedly, even with appropriate antibiotics. Your initial posts were concerning to me, because Bud's infection was being treated with Baytril…Baytril is a flouroquinolone. This classification of antibiotic is notorious for promoting mutation and resistance in MRSA infections and long ago was taken out of the treatment spectrum for both community(CA) & hospital(HA) acquired MRSA in humans. I would be very concerned about this possibility, particularly with the recurrence.

Because Bud developed this infection after ortho surgery, it shoud be assumed it is HA-MRSA & treated accordingly, although the line between treatment for HA-MRSA & CA-MRSA is blurred because of the widespread prevalence of the organisms. It sounds like they may have treated based on in vitro culture sensitivities, which might initially look like CA, but mutate rapidly.

Human medicine has waged the MRSA battle for decades now and treatment protocols are constantly evolving because of ongoing, ever changing drug resistance. If there is a treatment failure with a particular antibiotic, it is not repeated. Resistance is assumed while cultures are pending. The first line therapies for humans are available in veterinary medicine and it might be worth talking to your vet or pursuing another opinion about antibiotic options. I don't know why veterinary protocols are so contrary, but I would want to be sure the therapy was the optimal. There has to be some veterinary infectious disease specialist your vet could consult.

I work in an acute care facility with nationally recognized infection control /policies for resistant infectious disease. Every patient admitted to the hospital for any reason, is immediately screened for MRSA .  Even our therapy dogs undergo MRSA surveillance cultures quarterly and are not allowed to visit any long term care facilities and only a few other acute care facilities, who share our policies. MRSA is a zoonotic infectious disease, very easily transmitted between dogs & humans

A lot of public information you will find with a google search is outdated.The most recent human guidelines can be found in the Feb 1, 2011 issue of The Journal of Clinical Infectious Disease-vol 52, issue 3. You can find a direct link at the bottom of this article:

http://blogs.cd.....re/?p=1389

WYO
Member Since:
10 February 2011
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28 March 2011 - 9:02 pm
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Karen....You are so right about that perspective thing! Lovely idea on the tshirt but Im afraid we may scare some folksbig-grin I saw in the local newspaper today where someone had an add saying "hug a pug its cheaper than therapy"....it made me think of the pugapaloozas!

 

Isabelles's mom...Thanks for the post! There is soooo little info out there. We are on our 3rd local vet and had specialist in the metro area and our vet now consults with CSU.

We did do the culture and baytril was one of the few sensitive drugs and apparently there weren't many. Today we also got a topical that had also proved sensitive.

I did also contact the MRSA foundation who also contacted a specialist for me. It sounded like we were doing things per protocal with the lab and all. He told me that since it was in the bone it would be treated as osteomilitis was and that there was very little literature even for vets. To look through the human research.

 I was concerned at the time that we were not being aggressive enough but was told that since the "source" of infection was gone, this would be the treatment.

I am going to read up on the link you sent...thanks and we are following up with vet at the end of the week.Scary stuff!

littlemanjake
21
28 March 2011 - 9:10 pm
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The problem with the quinolones: MRSA very often is sensitive to it in vitro, but, the minute the organism sees the drug, it mutates. When they are used, it is in combination therapy. 

Osteomyelitis only refers to an infection in a bone & has nothing to do with the organism.  Removing the source of the infection has little impact on the organisms still present.

I can do a literature search for you & send some info if you'd like. You will find the current treatment protocols on the link above. I think you are going to have to look to human medicine and it's many years of experience for guidance

WYO
Member Since:
10 February 2011
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22
28 March 2011 - 9:27 pm
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I would be interested in reading what you found...thanks!

littlemanjake
23
28 March 2011 - 9:32 pm
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PM me with an address if you'd like. I'll try to pull some literature tonight, but the most up to date protocols will be those on the link.

Sorry you're going through all of this….

Las Vegas, Nevada
Member Since:
14 August 2009
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28 March 2011 - 9:35 pm
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Well gosh darnit Bud! Sorry to hear about the new infection. I'm with Karen! "It could be worse! So let's do a happy dance!"

Thank goodness for Isabelle's mom! Maybe that will help.

Give Bud a nose kiss from The Monkeyboys over here!

Her Retired AvatarComet - 1999 to 2011

She departed us unexpectedly  January 23, 2011 at the age of 12 1/2.

She was born with a deformed front leg and a tripawd all of her life.

In your heart, where I belong.
Member Since:
9 February 2011
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28 March 2011 - 10:00 pm
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I'm so sorry Bud has to deal with this again. He should be waiting for squirrels and spring, not wondering if he's going to get the right drugs to fix him up. You are probably going to have to be an aggressive, pushy advocate for him. I think you're up to the task. You're a mom, right?   laugh

If they're consulting with CSU, I'd like to think somebody's on the ball. But if they're using something that allows or even encourages mutations, as Cynthia said, it seems like somebody's sleeping through class. You had the amputation done at Alameda East, correct? They are really on top of things. One of the best clinics out there. Somebody needs to treat Bud like he's a human and not a canine. This is serious, frightening stuff. Keep us posted.

Shari

From abandoned puppy to Tripawd Warrior Dude, Dakota became one of the 2011 February Furballs due to STS. Our incredibly sweet friend lived with grace and dignity till he impulsively raced over the Bridge on 12-15-12.

Dakota's thoughtful and erudite blog is at http://shari.tr.....pawds.com/

littlemanjake
26
28 March 2011 - 11:27 pm
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It has to be extremely difficult for vets to determine an optimal treatment course as they have little experience with this virulent organism. MRSA often becomes a chronic infection once it establishes itself.

Most vets are probably not familiar or comfortable with the only drugs that may be effective and they are probably not approved for use in dogs….a few are barely approved for humans.The drugs themselves are arduous to manage and without any substantial data in dogs, dosing will be very challenging. The treatment cost may prove prohibitive and it can take months. Humans are still, after 30 years searching for a solution, which is why there is so much emphasis on prevention.

If the topical you are referring to is Bactroban (mupirocin), you might want to use it in Bud's nose -coat the front, inside with a small amount 3x/day for 5 days. The nares are a primary source of colonization for MRSA . This is not a permanent decontamination, but may help in the short run. 

WYO
Member Since:
10 February 2011
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29 March 2011 - 1:59 pm
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Thanks Shari for your support and concern

Cynthia. I am sending pm

Thanks to monkeybutt dogs for their nose kisses

I am gonna hope to heck this is just a bacterial skin infection!!!!

We are all praying around here, B made his preK class say a lil prayer with him too!

WYO
Member Since:
10 February 2011
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26 January 2015 - 11:49 pm
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It’s been almost four years since I began this thread on Tripawds and today I feel like it’s time for and update. Not necessarily for the eyes who may one day be searching but for me, for a way to digest what is happening. I needed to remember where we started, where we have been and where we are going. Four years ago, I was faced with the difficulty of discovery that we were 2 percenters. Out of the 98% that have full recovery from a hip replacement, we were the ones that got to endure the failure. We chose amputation after the femur didn’t heal. I cried and I was the one that considered euthanasia. I sat on the floor of the ICU with my kids so that my dog would eat and know that he wasn’t alone after his amputation, we were in this together!  I did the research online and found Tripawds. I virtually met my friend Shari whose dog Dakota, was also having his leg amputated the day before. We were in the same area. I was the one who kept calling for lab results to find out the bone infection was MRSA . I was the one this time who refused to give up when all of the drug options were failing and the bank account was dwindling. Bud got better and our lives were fuller. I made many virtual friends, some of who are my greatest  support even four years later  on days like today. We had some bumps to hop over like strained knee muscles, a smelly rear end and arthritis in the remaining leg. The saddest is when you recognize more dogs on the Tripawd banners and less on the forums. That’s when the visits to this site become less  frequent. There is a guilt when you know that your dog is the only surviving February Furball and journey is over  for the friends that you have met in this place.

 We have had a good four years and every day I have remembered to be grateful. There’s been rolling in the grass, rolling in the snow, trips to the mountains and trips to the lake. Bud has been a constant companion to myself, my husband and my children. He is the sweetest most well behave fella. He is easy going, loving and a paw holder. I don’t care what the experts say. I  know this dog understands every word  that I have to say. Each night, I sleep better knowing he is somewhere close by. When Bud turned 11 years old last October, I felt like we were on borrowed time. He is so large for his breed. He has had some vision loss, chronic bronchitis and less mobility.

Today was the day, the day you go the dogter and he says the words you absolutely don’t want to hear. “We are near the end of the journey, it’s time to think about pain managemet.” He kept using the word “end”. Bud’s rear end is giving out. He is using his leg more for balance than motoring around. He has severe pain in his back and remaining leg. So, now begins the downward spiral, the pain killer cocktail mixture and our first acupuncture appointment on Wednesday. I keep telling myself there is “no time stamp on his butt”, “he doesn’t know what the diagnosis was today” , “cry tonight and live in the moment tomorrow”, “Be More Dog ” and all of the many things I’ve learned here over the past four years.

I hope everyone that reads this is blessed with four years or more! I say prayers for those of you who are not. I also give thanks for all I’ve learned, my Bud dog and my friends. I’m a believer and I know there is NO end. There are changes of address. As my friend Charon and Tripawd angel Gayle have said many times….love never ends!

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Virginia







Member Since:
22 February 2013
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27 January 2015 - 9:54 am
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Got tears flowing over here...non-stop.

This journey you two are on has touched us all I. So many ways! Bud is LEGENDARY around here and the devotion you have for him...the determination and commitment to continue against all odds because you know your Bud...yeah, LEGENDARY!! We salute you both.

This is so hard, so darn hard. But because your love is sooooo great for Bud and because you will ALWAYS do whatsw best for Bud, you WILL be able to stay in the moment with him...you will savor each sacred second you won't worry about the tomorrows because you have Bud with you NOW! No, you will not let anything interfere with the time you and Bud have....because your love is so strong, so soul deep nothing can separate you two ever!

This whole thread you stated four years ago remains a source of information, hope and inspiration for everyone on this journey! Yep, Bud sure is liv i ng a life of purpose, a life of meaning and a life that will continue to touch the countless lives of many for an eternity!! Talk about a dog who is continuing to make a difference...WOW!!!!

And we ALL say no matter what it ks NEVER enought time with our furkids...EVER!! And we all cheer for those who do beat the crap out of statistics and we are all so deliriously happy for those victories!!! To spend one second o. "guilt"...NEVER!!! A victory for a dog like Bud is a victory for all of us!!! It is soooooo important to have the torch of hope...the torch of victories...to be carried for all who are on this journey, while in their earth clothes or in Spirit Energy form!

I know Bud will start feeling better once the meds get balanced. That will cheer you both up!! Many, many times these "palliative" treatments do wonders and I sincerely believe his will be the case for Bud!!!

Thanks for updating us and know that we are all here with you...and for you...and we understand like no others can.

Sending love and calming and serene hugs

Sally and My Eternal Light Happy Hannah and Merry Myrtle

Happy Hannah had a glorious additional bonus time of over one yr & two months after amp for osteo! She made me laugh everyday! Joined April's Angels after send off meal of steak, ice cream, M&Ms & deer poop!





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27 January 2015 - 8:21 pm
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Angel,

We are all with you on this.  Pulling for you & Bud.  You are a total inspiration to all of us and Bud beat MSRA.  Amazing that in itself is a major deal.  You guy haven't given up and you will keep trying until you know and Bud will let you know when its that time.  Its not easy no matter how much time you have. 

Thank you for updating us on Bud. 

Hugs

Michelle & Angel Sassy

sassymichelle-sm.jpg

Sassy is a proud member of the Winter Warriors. Live long, & strong Winter Warriors.
sassysugarbear.tripawds.com
07/26/2006 - Sassy earned her wings 08/20/2013

05/04/2006 -  Bosch, Sassy's pal, earned his wings 03/29/19  fought cancer for 4 months.

"You aren't doing it TO her, you are doing it FOR her. Give her a chance at life."

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