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carboplatin,,, low doses in dogs | Treatment, Recovery and Oncology

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carboplatin,,, low doses in dogs
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15 May 2018 - 12:09 pm
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I saw a new oncologist who is trained for the osteo vaccine,. She handed me a flyer that I read at home.. it says that most dogs don't have many side effects from chemo bec  a much lower dose is used in dogs than humans  for a longer life in dogs vs a cure in people.. My question is why aren't we using higher doses of chemo in dogs with the same goals in humans? ( I will ask this to my onco vet next week when simon gets his 4th chemo treatment..)

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16 May 2018 - 3:17 am
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Yes, that is a very interesting question indeed.

I also wondered about that when my Angel Eurydice was still here.

Please let us know what your oncologist says.

Hugs and cuddles 😘😘🐮💫✨🌟🌹

Eurydice 77kg/170lb Great Dane limping end of April 2016, amputation (right front leg/osteosarcoma) 4 May 2016 6 courses of carboplatin followed by metronomic therapy, lung mets found 30 Nov 2016. 3 courses of doxorubicin, PET scan 26 Jan 2017 showed more mets so stopped chemo. Holistic route April 2017. Lung X-ray 5 May 2017 showed several tennis ball size mets, started cortisone and diuretics. Miss Cow earned her XXL silver wings 12 June 2017, 13 months and 1 week after amputation and 6 1/2 months after lung mets, she was the goofiest dawg ever and is now happily flying from cloud to cloud woof woofing away :-) 

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16 May 2018 - 11:23 am
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You ask a great question!

My question is why aren't we using higher doses of chemo in dogs with the same goals in humans?

From what oncologists have told us...Simply put, their bodies can't handle it. And because their life spans are so much shorter than ours, even if they could handle the same level of chemotherapy doses, it would take them much longer to recover from the side effects. Thus it would reduce their quality of life in their very limited timeframes.

This is why veterinary oncologists always put quality of live as the #1 priority when treating animals. People medical doctors put obliterating the disease as their top goal, because humans generally have more tolerance to the chemo, and a longer time in which to bounce back from side effects.

I hope that makes sense. I'd love to hear what your oncologist says so do report back!

It's better to hop on three legs than to limp on four.™
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16 May 2018 - 5:48 pm
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thanks for your reply, Jerry...  I'm thinking that you have explained my question so well that I probably won't ask it any longer.. I will ask because you asked me to... thanks..  

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