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More options... need advice
28 March 2011
5:33 pm
Montgomery, NY
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Forum Posts: 100
Member Since:
21 October 2010
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Hi,

First… I did a search already and didn't find anything specific to what I was looking for (drug AND dx).

So, Champ is 9 months post-spleenectomy, and 5 months post-amputation – hemangiosarcoma. Our oncologist last week found a 1.5 cm nodule in his lung.

I just talked to her about options and, well, my research is not leading me to any answers so I'm hoping someone here (or Dr. Pam) may have a thought on this.

1. We are increasing his metronomic chemo to 7 days a week.

2. We are getting an xray in 3 weeks to see what the growth rate is.

3. The oncologist gave me some additional chemo suggestions — Carboplatin or Mitoxantrone

Here is where I am getting confused… Carboplatin is noted for osteosarcoma but no mention on hemangiosarcoma… Mitoxantrone is not mentioned for hemangiosarcoma either.

She had mentioned palladia but after some thought and more research we've decided against this.

I still want to fight this with anything I can. I just don't want to put him through chemo if it doesn't do anything.

Has anyone heard anything about these drugs in relation to hemangiosarcoma?

Thanks,

Joy

28 March 2011
6:45 pm
My heart lives at Rainbow Bridge

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28 November 2008
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Joy, no help with your questions, but wanted to chime in and let you know I'm sending tons of good thoughts for you and Champ.

Shanna & Spirit Trouble ~ Trouble gained her wings 3/16/2011, a 27 1/2 month cancer survivor, tail wagging RIP sweetheart, you are my heart and soul.  Run free at Rainbow Bridge.
We honor our fellow November Five members who will always remain forever in my heart: Nova – the lone survivor, live proud and long; Spirits Max, Cherry, & Tika – who made half the journey with us and greeted Trouble at the Bridge
http://k9cancer.org – a canine cancer support community
28 March 2011
7:55 pm
Here and Now

Team Tripawds
Forum Posts: 7744
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25 April 2007
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Wish we had better feedback for you, but don't have any direct experience there. Please let us know what you do find out. Give Champ a good ear rub for us!

"Dogs are born with three legs and a spare."
— Jerry G. Dawg (10/98-10/08)
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28 March 2011
9:26 pm
Las Vegas, Nevada

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Forum Posts: 4142
Member Since:
14 August 2009
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I'm so sorry Joy. Champ is such a fighter though.

I can't offer you any experience with chemo. Maybe someone can chime in.

Lots of hugs to you.

Her Retired AvatarComet - 1999 to 2011
She departed us unexpectedly  January 23, 2011 at the age of 12 1/2.
She was born with a deformed front leg and a tripawd all of her life.
29 March 2011
10:53 am

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Forum Posts: 1231
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22 August 2008
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HSA does not traditionally respond to much besides Cytoxan and Adriamycin.  It may be worth a try to use one of the other drugs but I do not have experience with them for that type of cancer.

Pam

29 March 2011
6:48 pm
Montgomery, NY
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Forum Posts: 100
Member Since:
21 October 2010
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Thanks for the reply. Unfortunately that is what I am reading in the research as well.

My only thought here is this…

The tumor on his spleen was very small (golf ball sized) for a spleenic mass. The cancer in his femur had been diagnosed almost 5 months earlier by xray. There were no other masses in his abdomen, lungs, or in any other bones. We had xrays done of every bone in his body. After the amputation the pathology on the femur was inconclusive as to the type of cancer.

I know it's far-fetched but…

Could the cancer that was in the bone have osteosarcoma and therefore a separate cancer from the spleen? My oncologist is sure that the femur was a metastatic lesion from the hemangiosarcoma… but… why would the leg present first? If the spleenic mass had been there first, wouldn't it have been MUCH larger than golf-ball sized? Wouldn't there have been other masses?

If it's possible that this is metastisis from an osteosarcoma, might we see some benefit from carboplatin?

I know… I'm grasping at straws but… if it were my kid I'd be doing the same thing… doesn't he deserve this??? I love my baby…

Thanks,

Joy

29 March 2011
7:04 pm
Las Vegas, Nevada

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Forum Posts: 4142
Member Since:
14 August 2009
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Joy,

Of course, I know nothing about cancer except with hemangio but I never got a diagnoses until it was too late on both Rugby and Comet.

 

Tsuvsha, a tripawd member had hemangio in her bone when they thought it was osteo.  It was hemangio.  It later showed up in her vital organs.  Here's her story:  http://labrador…..pawds.com/

 

You may want to search her member ID labradorim to see her forum post since we had very extensive conversations about it.

 

Best wishes.

Her Retired AvatarComet - 1999 to 2011
She departed us unexpectedly  January 23, 2011 at the age of 12 1/2.
She was born with a deformed front leg and a tripawd all of her life.
30 March 2011
12:12 am
Calgary, AB
Member
Forum Posts: 268
Member Since:
30 January 2010
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Sorry I've no words of wisdom but I just wanted to let you know I'm thinking of you and sending pawsitive thoughts.

Hugs and wags,

Laura, Kali and Angel Tai

Tai – 9 yr old lab. Diagnosed Osteosarcoma Dec 18/09. Front right leg amputated Dec 21/09. Started chemo Jan 7/10. Lung mets discovered Sept 16/10. Valiant to the end on Oct 26/10 when cancer reappeared in a leg and we made the decision to set her free. Forever in my heart where not even cancer can take her from me.
30 March 2011
10:31 am

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Forum Posts: 1231
Member Since:
22 August 2008
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HSA can show up in the bone or other organs first and due to your dog's breed this is the most likely scenario.  Did he already have Adriamycin injection?  If so then I would try carboplatin because it works in a different way.  Mitoxantrone is similar to Adriamycin.

Pam

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